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Rifaximin and Nausea: What Users Say

Brand names: Xifaxan

Nausea: mentioned by 6 users (3.8%)

Based on user experiences from 156 Rifaximin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

bloating 16.7%
diarrhea 14.1%
gas 11.5%
constipation 7.1%
cramps 5.1%
pain 5.1%
stomach pain 4.5%
nausea 3.8%
upset stomach 3.2%
headaches 2.6%

Reviews for Rifaximin

Commonly mentioned side effects
  • Thu...
  • Taken for less than 1 month
  • June 3, 2020

Rifaximin for Irritable Bowel Syndrome with Diarrhea "I had terrible nausea all the time that was worse about 2 hrs after eating, my stomach would swell up with gas, I was belching but could not throw up, retaining water and terrible gas pain below my sternum. I have heart issues requiring water pills and blood pressure meds. I was stopping taking meds because of nausea and watery and gassy diarrhea, thought it was the end of me. Took all tests which were normal, probiotics made it worse. Finally convinced my Dr to try Xifaxan because read about SIBO on internet. The first 14-day course gave me 80% relief and felt much better, after 3.5 months symptoms came back so had another 14-day prescription. Felt good, now it’s been 3.5 months and symptoms are coming back. Is this possible? Can you stay on Xifaxan long term with 3-4 month intervals? My Dr is unavailable because of COVID virus. Any advice please... thanks"

10 / 10
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138 Report
  • The...
  • Taken for less than 1 month
  • October 24, 2020

Rifaximin for Irritable Bowel Syndrome with Diarrhea "I’ve had IBS-D for as long as I can remember. Finally cracked and went to a doctor. After 2 months of blood work, CT scans, and a colonoscopy, they didn’t find anything wrong. I was depressed hearing, 'we don’t know what’s wrong.' The doctor calls me one day and says he wants me to try a drug - I’d do anything at this point for relief. In comes Xifaxan. I had really bad nausea the first day for about an hour, then nothing after that. After day three, I didn’t have any pain, bloating, or mad dashes to a restroom to unload. I was having normal one-a-day bowel movements with 'ghost' wipes. It lasted about a month and a half, and the symptoms are starting to reappear. I have a prescription for 3 treatments, so I’m going to go at it again and see what happens."

10 / 10
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20 Report
  • SMi...
  • Taken for less than 1 month
  • August 19, 2016

Rifaximin for Irritable Bowel Syndrome with Diarrhea "Sadly, this medication gave no relief at all and actually made things worse... Severe nausea and vomiting on top of constant diarrhea, not an easy thing to multitask if you know what I mean. But hey, all meds work differently for different people. Hope others had better luck than I did."

1 / 10
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34 Report
  • Che...
  • July 15, 2017

Rifaximin for Irritable Bowel Syndrome with Diarrhea "I have IBS with diarrhea. Out of pocket price $500.00 for Xifaxan 550 mg, three pills a day. It did not work for me at all. After two weeks of the pills diligently taken, waste of money. I had no side effects, but the pills did not work for me, the diarrhea persists, as does nausea, sweating, and stomach cramps. I have run out of ideas, as has the doctor. Don't waste your money."

1 / 10
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21 Report
  • No...
  • August 21, 2021

For Irritable Bowel Syndrome "Got rifaximin prescribed for SIBO without an official diagnosis. No testing was done for SIBO—just the doctor's assumption from the symptoms I was having. I took it for 3 days (3x a day), and I HAD to quit. The stomach pain/cramping is unbearable. I have bouts of nausea constantly, and I have more diarrhea than ever. I wasn’t even suffering from diarrhea before this drug. Pretty disappointed and upset. I hope these side effects are not long-term, considering I cut my dosage short—for obvious reasons."

1 / 10
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1 Report
  • Dan...
  • Taken for less than 1 month
  • March 1, 2022

Rifaximin for Irritable Bowel Syndrome with Diarrhea "Prescribed for my IBS-D. On the second day (5-6 doses), my nausea was unbearable. Stopped taking this very expensive med."

1 / 10
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1 Report

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