Creon and Headaches: What Users Say

• gir...
• Taken for less than 1 month
• July 8, 2016

For Pancreatic Exocrine Dysfunction "I was prescribed Creon for EPI. While on this medication, I experienced very little, if any, relief from my symptoms. The side effects were horrendous - headache, hot flashes, coughing, memory issues (straining to remember words), and joint pain in my upper leg and tailbone. Within 24 hours of stopping the medication, all side effects disappeared."

• Fed...
• Taken for less than 1 month
• March 7, 2019

For Chronic Pancreatitis "After a gastric bypass 4 yrs ago, then followed by gall bladder removal, I was left with chronic unpredictable diarrhea, pain, bloating, and nausea. Recent tests showed I had EPI (Exocrine pancreatic insufficiency) and my pancreas was not producing enough, if any, enzymes. A week ago, I was prescribed Creon 10000 by the hospital. I feel so ill taking them. The pain and bloating have gone, but I am still getting diarrhea, bad nausea, a vile taste in my mouth that taints everything I eat/drink, and awful headaches. I take 2 capsules with a meal twice a day, then 1 with any snacks. I cannot eat normal meals due to the gastric bypass, so I tend to graze throughout the day every 2/3 hours. Is this normal, and will the symptoms go eventually, or will it always be like this? I am truly sick and tired of it all."

• Gri...
• April 3, 2021

For Pancreatic Exocrine Dysfunction "I am 56 years old with pancreatic cancer. After 3 days of taking Creon, I thought I was going to die. Except for diarrhea, I experienced every side effect on the list. Excruciating abdominal pain, constipation, bloating, headache, etc. On a scale of 10, my pain was at 10. My husband, who is a nurse, was puzzled, and I realized that the only thing I had changed was that medication. I stopped taking it immediately, and it took me a week to recover. Not blaming anybody, but if it happens to you, stop taking it immediately and talk to your doctor."

• way...
• Taken for 1 to 6 months
• January 13, 2023

For Pancreatic Exocrine Dysfunction "Creon has done nothing to relieve my symptoms. I am still suffering from bloating, feeling like vomiting all day, headache, and I have lost 30 lbs in three months. I am going to ask the doctor to switch me to Zenpep. Creon has a 50% approval, whereas Zenpep is 74%, so I'm hoping it will work for me."