Kesimpta for Multiple Sclerosis User Reviews (Page 2)

• Drea
• Taken for 1 to 6 months
• December 1, 2022

"1st dose was November 9th, no issues! I had a mild headache the next day but I always get headaches. I already deal with chronic fatigue, pain, and numbness, so no noticeable changes to that! I actually got a burst of energy for about 4-5 days so that was awesome! I was on Ocrevus for 3.5 years and was sick of the 6 hour infusions so I asked to switch! The next dose is December 9th! I'm extremely happy that I switched! I'm so sorry for everyone that has had horrible reactions! Take care to all you MS'ers out there!"

• Jacob...
• Taken for less than 1 month
• December 2, 2022

"The 1st dose was rough for the loading dose. 1st one, I experienced chills and shakes that were uncontrollable. The absolute worst headache I have ever experienced, and I felt like I needed to vomit but couldn't. Taken at 1900, awoke at 2300, and I wasn't able to fall asleep again until 0400. Did not want to take the next dose, but did. Minor headache, no chills, taken at 1900, headache woke me at 0300, but I was able to get up and take acetaminophen and back to bed. 3rd dose, I had read about taking Benadryl 1 hour prior to dosing with acetaminophen. Taken meds at 1800, dosed at 1900. Woke about 0330, but was able to drink some water and went back to bed. By the 3rd dosing, I believe I was acclimated to the drug, but I am worried about a repeat of the 1st experience now that it is going to go to monthly. I do not see improvements in symptoms, e.g., fatigue, room spinning, tingling in arms and legs. I will update after about 6 months of injection."

• Infor...
• Taken for 1 to 2 years
• April 21, 2022

"I love Kesimpta. Not having to worry about veins being blown out by infusion treatment. I did run a 104 fever from the first injection, but the second and third were fine. I began to feel my feet again after the first injection. Mixed emotions about that. For the time being, I can't really say if I'm slowly getting worse or better. Good and bad days. I did have an icy hot sensation in my leg for a month after taking the first 5 doses, which vanished after steroid treatment."

• HHD
• Taken for 2 to 5 years
• July 24, 2024

"I feel that it's been working very well for me. I take it once monthly at home. In the initial build-up phase, I had some very minor breathing tightness and stomach problems, but that ended after I reached maintenance level. Recently, I've had some infections that I haven't felt I needed to take antibiotics for, just working on natural solutions, and they're improving. Otherwise, I'm very happy with the medication; it's easy to take, just once a month at home with no negative aftereffects, and I just go on with my day."

• Kesim...
• Taken for 1 to 6 months
• April 19, 2023

"Being realistic about MS meds and side effects, I know they cause pains, fatigue, and other unfavorable side effects. I got through the loading doses, the side effects were akin to having a short but very severe flu. I was prepared for that. I tend to feel like a normal person towards the next dose when enough time has passed. I like not having constant severe pain like I did on copaxone. However, I wish that medical professionals would stop minimizing and undertreating the pain of this disease and how it can be further aggravated by taking DMDs. There are times on Copaxone and Kesimpta that I dread the myalgia resulting from the scheduled dose because I know the aleve or advil the doctor nurse has emphatically declared will cure, won't fully help. The increased risk of sunburn was surprising and the constant scalp irritation even with intense conditioning and hydration has been baffling. That being said, I'm still grateful to be functional with a medicine that only requires once a month dosing."

• Great...
• Taken for 1 to 2 years
• June 27, 2023

"I have been on Tysabri, Tecfidera, and Gilenya. I had liver issues with Gilenya, anaphylactic shock with Tecfidera, and Tysabri was OK, but it was too time-consuming to get the monthly infusions. Kesimpta has been by far the best medication I have taken to treat RRMS. I have been on this for over a year and had one minor flare-up, which was easily treated with a pill steroid. I am very happy with this drug, and I haven't felt better since my diagnosis in 2015."

• Kesim...
• September 1, 2022

"It’s not working I have got worse. Since I was taking Tysabri but got the JCV virus from that I had been on that for 13 years. The Kesimpta my legs are feeling like they are on fire. Once I stand in the morning after a few minutes my legs go numb!! Right now my toes on both feet feel like they are on fire can’t stand this!!"

• Donna
• Taken for 1 to 2 years
• August 13, 2023

"Have been on Kesimpta for 20 months (I am 67). No side effects even with loading doses. At about the 10-month mark, I felt like I turned a little corner and was fully in my system. Only thing is I feel like my walking has declined over these 20 months. It's easy to use and painless, and some months I feel pretty good. Just concerned about the decline in walking, so I am trying to increase my daily steps to see if that helps. Overall, I like it."

• Rob
• Taken for 1 to 6 months
• September 8, 2024

"I started Kesimpta in June 2024. The first shot of the loading doses caused severe flu symptoms, but the next two loading dose injection symptoms were mild. The first maintenance shot went well. The next two did not. Around 44 to 48 hours in, my blood pressure got dangerously high, and my heart rate was very high. I was told that since it happened 2 days after the injection, it was not Kesimpta-related. Quite frankly, I am afraid to take the October injection. I don’t know what to do. I do think the symptoms are Kesimpta-related."

• DLewis...
• Taken for 1 to 6 months
• April 25, 2023

"The medication has a positive effect on my condition. My mobility has improved greatly. Which, I'm more than thankful for. The negative that I've experienced is currently a breakout on the back of my right hand, a small reaction on my left hand, and both my arms. These are a small irritation, which I'll happily deal with for the positive effects the medication has had/ having on my overall condition."

• Zoano
• Taken for less than 1 month
• June 12, 2022

"Felt awful after my initial dose and had signs of an allergic reaction, so I was given antihistamines and an EpiPen for my second injection, but it was absolutely fine. No side effects. Was on Tysabri for the past 7 years, which I loved, but my JC virus score was increasing too much."

• Just_...
• Taken for 6 months to 1 year
• May 1, 2023

"I have been on Kesimpta for 10 months so far. I recently had more scans and found out that I had new lesions and have developed numerous black holes throughout my brain. The damage may have occurred prior to starting treatment, but overall I do feel a bit better so I am continuing treatment. The only side-effects have been fatigue and fever for 3-5 day after injection."

• Glider
• Taken for 6 months to 1 year
• March 25, 2023

"Has effectively stopped further MS activity as shown on MR tests. However, after four months of use, I have developed side effects. Severe pain in my leg, like flashes during the night and lasting about three weeks, after sore foot and burning sensation upper side of the foot. Tried massage (professional) which seemed to help. Experience “trigger finger symptoms “ in both hands; thumb and point fingers. Also burning sensation in the leg muscles when getting up from a chair/bed. I have some cramps feet and lower legs. Calf-muscles locking. Goes away when standing up. Have been using Kesimpta since July 2022. So 9 months. Dosage 1/month. Very easy to use. No side effects when taking the medicine (within 24 hours) so far."

• Katy
• Taken for 1 to 6 months
• June 15, 2024

"I have had eight doses, including the loading doses. My side effects have mainly been exhaustion, though I have slowly lost my appetite, and recently felt highly nauseous. My MS symptoms are steadily declining, pain, weakness, stiffness, etc., but without Kesimpta I may be a whole lot worse. The medication needs at least a year to really work too. Overall, without any other real choices, I am happy to keep having the Kesimpta injections."

• Markie
• November 4, 2022

"Have been taking for 14 months. Periodic stints of feeling a little better and able to get around pretty good without my cane. Yesterday I got bold and raked leaves in my yard. Today can hardly walk. Back to my cane again. Last couple of months my sinuses have been excessively, constantly draining. My PCP started me on an antihistamine and Mucinex. Had no positive results. Then I researched for potential side effects of Kesimpta finding nothing listed for Kesimpta and sinusitis. Then researched Ofatumumab extensively. Did find that Azerra was the name of the Ofatumumab given for CLL (Chronic Lymphatic Leukemia). Found several sites indicating Sinusitis was a common side effect of Azerra. One listing indicating Saline Nasal Spray may be beneficial. I did try the saline nasal spray with extremely positive results. Finally am able to sleep without choking on the continuous nasal drainage from choking me awake frequently at night. Now able to do things around my house."

• Cc1002
• Taken for less than 1 month
• January 22, 2023

"First time taking my Kesimpta injection last night, it was painless, was fine for the first hour. After 1 hour I had chills/back pain. After 4 hours I had fever, got to 101.09 went to bed used ice pack. That helps and took the fever down. Next morning felt 100% but I have itching on my face. Going to call Dr to see if this is serious. Hope everyone is doing well and good luck"

• LuLu
• Taken for less than 1 month
• May 20, 2022

"I have taken my first dose two days ago. Due to Covid, insurance and medication shortage I was without any medication for 7 months. Begged for a steroid treatment, which I hate and my neurologist wouldn’t do it. I have been nauseous, mild headache, very tired and HOT! It’s humid here (SC) and the night sweats were so bad. The reviews have been helpful. I will know more when I get to my second and third dose. Not given up yet. Keep your fingers crossed!"

• Stacey
• Taken for 1 to 2 years
• May 3, 2023

"I have been on Kesimpta for 2 years. I have a bit of a love /hate relationship with it. Pros are it was only one jab a month after the initial start-up jabs. Minimally impacts my life and It’s quick and simple. Cons are that it stings when I do the injection, and I immediately get a 24-hour headache the minute it hits my system. I do get a little more poorly if I get an infection."

• Diana
• Taken for less than 1 month
• November 28, 2022

"I have finished the 3 week shots. Each time it did get better. I still get tired on the 5th or 6th day after the shot. I was taken off Ocervus cause getting an infusion all at once was shocking my body and I have a weak stomach, to begin with. In the beginning, I know there will be some side effects until your body gets used to it and trying to work with it. I am hoping this will keep my MS steady. Good luck everyone. Think positive"

• Teresa
• Taken for 6 months to 1 year
• October 26, 2022

"Started in late Jan- got sick (fever, flu-like symptoms) only after 1st dose and have had no problems since then. I do take ibuprofen and benadryl 1 hour before injection, and I inject at night right before bed. Too soon to know if it's working, but very easy to take."

• Darren...
• Taken for 6 months to 1 year
• March 15, 2024

"I was diagnosed with RRMS. I've been on Kesimpta for 10 months. It is very convenient and easy to administer. So far, I've had no issues with Kesimpta. My recent full MRI showed no further progression."

• GroovyP
• May 1, 2023

"I just finished my initial doses. All were different, the first dose I got a sore throat, itchy without a rash, went to bed, and woke up with the most excruciating muscle and joint pain I've ever experienced. Dose number two hurt more than the first, my throat was sore and I was again itchy all over without a rash, but no body aches. Dose three was only the itchiness, but I just didn't feel good for about a week. I had all my injections on a Sunday, for the first two on Thursday I had some minor vertigo and a short-lived temp increase to about 101 F. I rotated my injections on my thighs, however with each injection, I felt like I received an injection in my left upper arm. Very weird."

• elisa...
• Taken for 6 months to 1 year
• August 9, 2024

"First dose - horrible flu-like symptoms with fever. Tylenol helped. After the first dose, it was better with no noticeable side effects. I have taken it for close to a year. Over time, I realized it is likely triggering heart arrhythmias. I seem to have less pain when I take it. Other than that, I don't know for sure if it is helping or not."

• Chuck
• Taken for less than 1 month
• September 17, 2023

"Was on Ocrevus for about 3 years, seemed to not be working as well as before, so the doctor switched me to Kesimpta. Just finished my first 3 shots with no real side effects, other than feeling a little tired after the first two. Looking forward to seeing how it works in the future."

• IHateMs
• Taken for 1 to 6 months
• April 27, 2022

"About to take second dose. I don’t like how I feel on this drug. Migraines are worse. I’m more fatigued. I began the drug because of its ease of taking once a month via self injection. I wanted to go back to work full time. However, I’m too tired to do the job. Can’t think clearly because I’m too fatigue. Going back to Tysabri."