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Linezolid and Nausea: What Users Say

Brand names: Zyvox

Nausea: mentioned by 10 users (31.3%)

Based on user experiences from 32 Linezolid reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 31.3%
diarrhea 15.6%
tiredness 15.6%
dizziness 9.4%
fatigue 9.4%
insomnia 9.4%
upset stomach 9.4%
yeast infection 9.4%

Reviews for Linezolid

Commonly mentioned side effects
  • Anonymous
  • Taken for less than 1 month
  • June 21, 2012

Linezolid for Methicillin-Resistant Staphylococcus Aureus Infection "I contracted MRSA in my right foot second toe. My doctor gave me Zyvox because I had MRSA before, and it was very hard to heal. It worked very well in clearing it up. It was the worst 2 weeks of my life. I had nausea, diarrhea, weakness. I felt horrible. I suppose it was better than losing my toe. It worked for me. I would use it again if the need arose. I am just glad my insurance paid for it, or I couldn't have used it."

8 / 10
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39 Report
  • Anonymous
  • September 12, 2009

Linezolid for Methicillin-Resistant Staphylococcus Aureus Infection "I was diagnosed with MRSA in the hospital. The infectious disease doctor said I was lucky that it responded to Zyvox. It's a much better and easier alternative to IVs for a month. The medicine did make me feel nauseous. It was, however, very effective."

8 / 10
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44 Report
  • San...
  • August 5, 2009

Linezolid for Methicillin-Resistant Staphylococcus Aureus Infection "I acquired a Staph infection after rotator cuff surgery. It was as painful, if not more painful, as shingles. Have been taking Zyvox for 14 days, with 3 to go. It has worked to heal the sores. The problem is the constant stomach upset and nausea. It is a very unpleasant feeling, somewhat like seasickness."

9 / 10
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42 Report
  • Kri...
  • October 13, 2009

Linezolid for Methicillin-Resistant Staphylococcus Aureus Infection "I am starting on my second week of a 28-day regimen of Zyvox. I have had a staph infection for over a year that will go away after being lanced and then come right back in a different place. So far, the infection is gone, and I am praying that it doesn't come back. There has been some nausea, stomach aches, and being more tired than normal. Would take that any day over the pain of a severe staph infection."

10 / 10
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40 Report
  • ali...
  • October 10, 2008

Linezolid for Pneumonia "In February 2008, I fell ill to influenza A and ended up with double pneumonia. After a 7-day hospital stay in the ICU, I begged to go home, and the doctor prescribed Zyvox. This antibiotic did its job and cleared up my pneumonia and also a MRSA sinus infection that I had tried dozens of other antibiotics for with no results. There weren't many annoying side effects, which was a welcome relief. I did have some dizziness, but nothing severe, also, a little nausea from time to time."

10 / 10
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35 Report

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  • Sha...
  • February 28, 2016

Linezolid for Methicillin-Resistant Staphylococcus Aureus Infection "I have osteomyelitis of the temporal bone. In the hospital for 1 week, sent home on IV Vancomycin and Cefepime. After 4 weeks, back to the hospital for chills and fever. In for a week, low blood and increased iron...all due to IV. Sent home on Zyvox and Levaquin for 30 days, hoping the infection has cleared (will find out after finishing meds). Side effects: nausea, diarrhea, dizziness, cannot eat as nothing tastes right, GERD, pressure in the sternum area, extremely tired, short of breath, yeast infection, insomnia, muscle and joint aches, emotional, and today red spots on skin. Needless to say, I feel horrible! Hopefully, this will all be over soon but don't feel I will ever be the same. If this works, then it's an amazing, wonderful drug. However, it's very expensive. Thank goodness for patient assistance!"

8 / 10
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  • Anonymous
  • November 28, 2015

Linezolid for Skin and Structure Infection "I have been on IV Zyvox for almost 2 weeks now. I have a bone infection. I have been on several IV antibiotics, and this is the last one we are trying. I am experiencing side effects (nausea, vomiting, very loose stools several times a day, stomach pain, headache), but am trying to push through the pain as I am scheduled to come off the Zyvox on Dec. 7th."

7 / 10
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10 Report
  • Jen...
  • July 3, 2015

Linezolid for Skin and Structure Infection "I have been on Zyvox for 6 weeks now and have 6 more to go. My experience with this medication is not a pleasant one. I am on 2 anti-nausea pills plus the Scalpone patch to be able to eat and not throw up. I am also taking a pill for loose stools so I stay hydrated. Spending a day in the emergency room getting fluids is not a good way to spend your husband's day off. My legs and feet swell to double their size and are very painful. I have no option but to be on Zyvox since I failed vancomycin. My doctor keeps an eye on me, but the brown tongue and funky taste are disgusting. I pray none of these side effects are permanent."

7 / 10
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9 Report
  • Ste...
  • Taken for less than 1 month
  • June 22, 2017

For Methicillin-Resistant Staphylococcus Aureus Infection "I'm taking oral Linezolid, 600 mg. Dosage is every 12 hours. I'm in a rehab center for an amputation below the knee. I'm a 61-year-old male with type 2 diabetes. At first, I felt nothing, but now into my 13th day, I feel nauseous at times, loss of appetite, and tired/sleepy. I also feel weaker than before and it's harder to do my physical therapy. I can't wait for my 14-day period to end."

5 / 10
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  • Drk...
  • Taken for less than 1 month
  • October 2, 2022

For Methicillin-Resistant Staphylococcus Aureus Infection "I was prescribed this medication for MRSA. While it did work effectively, it caused extreme anxiety and severe insomnia, as well as a slight nauseous feeling with malaise. I must assume this is a very potent antibiotic, as it has potent side effects."

6 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.