Isoniazid and Nausea: What Users Say

• Jam...
• Taken for less than 1 month
• April 13, 2018

For Tuberculosis, Latent "Started taking isoniazid (INH), and about a week later felt horrible: nausea, stomach pains, diarrhea, extremely dizzy, hard to even sit up in a chair, no appetite. This lasted 4 days after I stopped the medication. Started feeling better on the 5th day I started back on INH, all was good until the 5th day, sick all over again, lost 6 lbs. I'm a skinny guy as it is. I think I'm gonna take my chances of 5-10% of getting sick later with TB. Never felt so bad, could hardly stand up, felt like I was going to pass out. My liver is more important than a 5-10% chance of getting TB."

• ony...
• May 28, 2017

For Tuberculosis, Latent "It's my third month of treatment for latent TB. My ALT (liver enzyme) increased already three times more than normal at 100. I experience chills, fever, joint pain, tingling in my hands and feet, nausea. I'm very worried about my liver damage too. My doctor told me to get blood work every week, and if I start vomiting, to stop the medication and call her right away. I'm so upset, if I stop the medication, I might get active TB at one moment in life, and I would need more medication. If I continue, I don't feel well, and I don't know what effect it would have in time on my body and especially on my liver. Maybe I should have refused the treatment in the first place. Life sucks. :( P.S. I take one tablet of Isoniazid 300 mg with vitamin B6 25 mg every day."

• Lee...
• October 9, 2019

For Tuberculosis, Latent "My experience on isoniazid over the last two months has been bad. I was wanting to be positive, but it has been a struggle to say the least. I was prescribed 300 mg a day (30 yo female, 60 kg weight), and after the first few days, I had extremely bad diarrhea, fatigue, body aches all over, and felt nauseous. I pushed through 14 days of this and then had to stop due to being so ill and off work. My doctor then told me to rest a week and then try again, this time doing 1 week on 100 mg, then week 2, 200 mg, and finally getting back up to 300 mg. This really helped my body adjust a bit better, still had days off in bed, sleeping, chills, cramps in my legs, not eating, feeling bad, but it helped. Personally, it’s a huge whack to the system and takes an emotional toll being so sick and tired all the time. I have lost a lot of my hair too, which is not fun, and I was told it’s quite normal! Hopefully, it’s all worth it!"

• Eli...
• September 22, 2015

For Tuberculosis, Latent "Overall, I'm sure this medication is very effective, but after taking it a week, I started getting nausea and stomach pain, especially after I ate. I'm sure some of this has to do with the fact I ate cheese sometime, as you have to be careful not to have foods high in tyramine. But I started to have general stomach pain, cramping, and tenderness. So my doctor said today that I have to stop taking the meds. Now I'm going to the infectious disease specialist."

• Dav...
• Taken for 1 to 6 months
• November 14, 2021

For Tuberculosis, Latent "After 4 days of isoniazid for latent TB, I experienced bad diarrhea. Disturbed rest at night when it happened mostly (3-4 times) after midnight till early 7 am. After 3 months, rashes, fever, and nausea happened. Finally, it was so bad I required A&E admission in hospital. Liver ALT and Asp all shot up to very dangerous levels around 900. Stop isoniazid now when doc confirms is the cause of this."