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Isoniazid and Moody: What Users Say

Moody: mentioned by 4 users (14.3%)

Based on user experiences from 28 Isoniazid reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 17.9%
diarrhea 17.9%
liver damage 17.9%
nausea 17.9%
moody 14.3%
fatigue 10.7%
stomach pain 10.7%
upset stomach 10.7%

Reviews for Isoniazid

Commonly mentioned side effects
  • Anonymous
  • October 25, 2011

For Tuberculosis, Latent "I'm currently on this medication plus vitamin B6 for a positive TB skin test. I've been taking it for about 4 months now. I'm scared to death. I wonder if I will be able to go through these 9 months without serious side effects like liver damage. Haven't experienced any side effects so far. I seem okay. 5 months to go. Hopefully, nothing serious happens. I'm so moody lately. My coworkers say I now have an attitude."

7 / 10
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  • Sti...
  • June 24, 2010

For Tuberculosis, Prophylaxis "I'm still here, so I guess it worked - but it was a rough, horribly rough 9 months - it helped that I was already on medical leave (and that the hospital took responsibility for the exposure) - Isoniazid is literally a sort of (failed) anti-depressant that works against TB, but is also pretty harsh on the liver, so I had to take Vitamin B6 for 9 months too. I was pretty moody, crazy, aggressive - not my normal self... it was a long 9 months. I can't understate how mood-altering this medicine was - not in a good way. I was embarrassed to talk about it, which made my behavior all the more odd to my friends and co-workers, but once I explained it, I got some support - anyhow, I wish I had done that from the start. On the plus side, I'm still here!"

7 / 10
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  • nan...
  • Taken for 6 months to 1 year
  • October 17, 2019

For Tuberculosis, Latent "I've been taking isoniazid 300 mg with vitamin B-6 50 mg for almost 4 months now, and I have 5 more months now - it is for tuberculosis (TB). I have been depressed and moody all day until today. I keep crying and I am not feeling good at all."

4 / 10
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7 Report
  • Lat...
  • Taken for 1 to 6 months
  • June 11, 2022

For Tuberculosis, Latent "I've been taking isoniazid for 4.5 months now, and my mood has been deteriorating slowly but surely for the last month. I have struggled with fatigue and memory loss since the beginning, and this improved a bit since then but is still hard. But mostly now, I feel incredibly low, teary, overwhelmed, and anxious all the time. I don't feel like I can keep going, but I know I have to."

4 / 10
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