Isoniazid and Fatigue: What Users Say

• Lee...
• October 9, 2019

For Tuberculosis, Latent "My experience on isoniazid over the last two months has been bad. I was wanting to be positive, but it has been a struggle to say the least. I was prescribed 300 mg a day (30 yo female, 60 kg weight), and after the first few days, I had extremely bad diarrhea, fatigue, body aches all over, and felt nauseous. I pushed through 14 days of this and then had to stop due to being so ill and off work. My doctor then told me to rest a week and then try again, this time doing 1 week on 100 mg, then week 2, 200 mg, and finally getting back up to 300 mg. This really helped my body adjust a bit better, still had days off in bed, sleeping, chills, cramps in my legs, not eating, feeling bad, but it helped. Personally, it’s a huge whack to the system and takes an emotional toll being so sick and tired all the time. I have lost a lot of my hair too, which is not fun, and I was told it’s quite normal! Hopefully, it’s all worth it!"

• yel...
• Taken for 6 months to 1 year
• January 29, 2019

For Tuberculosis, Latent "1. First time I used Isoniazid, I ended up having to give it up as my blood count was out of this world. Found out later that it was due to a gastro complication and had my sphincter removed due to a gall bladder removal years prior. 2. Second time I used Isoniazid, the first tablet gave me a burning sensation that I thought I had to go to the hospital. I stopped it. 3. Lost all of my teeth because of an acute infection and had them all removed. 4. Went to see another doctor who put me on Isoniazid again, but I am in my 9th month of treatment and only 3 more pills to go! I feel still exhausted and so fatigued, but hoping that this will stop when I have totally taken the 9-month treatment. Gravol (for stomach sickness) is my best friend right now."

• Lat...
• Taken for 1 to 6 months
• June 11, 2022

For Tuberculosis, Latent "I've been taking isoniazid for 4.5 months now, and my mood has been deteriorating slowly but surely for the last month. I have struggled with fatigue and memory loss since the beginning, and this improved a bit since then but is still hard. But mostly now, I feel incredibly low, teary, overwhelmed, and anxious all the time. I don't feel like I can keep going, but I know I have to."