Dolutegravir / lamivudine and Depression: What Users Say

• NJ ...
• Taken for 1 to 6 months
• September 15, 2022

For HIV Infection "HIV+ since 2012, started on Stribild, then Genvoya, then Biktarvy, and now Dovato. Dr. switched me because of slightly decreasing kidney function labs over the years. Dovato maintained undetectable, labs are all good, undetectable, and renal function has stayed the same. I do notice some mild depression on Dovato, but nothing real horrible... I give it a 10/10."

• Fea...
• Taken for 1 to 2 years
• March 23, 2023

For HIV Infection "I have been taking Dovato for a year now, but I constantly feel full and hungry at the same time. I have gained 30 lbs and slowed down a lot. Sometimes, I feel sad and have dark thoughts that I don't like, but my viral load and CD4 count are excellent. I have decided to go back to Atripla, which I took for 10 years and made me look healthy, with a model's frame and generally happy with my life. After Atripla, I tried Genvoya for 2 years, but it made me feel sad and like I was carrying bricks around my legs 24/7. I also gained weight rapidly and developed a kidney stone while on it, which is still in my kidney three years later. I really hope I don't have to switch medications anymore because this experience is scary and unsettling."

• Anonymous
• February 11, 2025

For HIV Infection "Least side effects of all medications I took for HIV. Currently having problems with depression, anxiety, weight gain, high triglycerides, high cholesterol. I am not sure about muscle pain or just sore from workout. I am doing omega-3 ethyl esters 2 mg, niacin low flush, D3K2 vitamin. I work out hoping it will help with side effects. Last blood pressure was 145/62, pulse 52."