Desmopressin for Hemophilia A User Reviews
Brand names: DDAVP, Minirin, DDAVP Nasal, Nocdurna DDAVP Rhinal Tube
- DCW
- Taken for 5 to 10 years
- December 21, 2021
"I use DDAVP injections for my mild haemophilia A to prevent bleeding prior to surgery and treat spontaneous or injury induced bleeds, it always works well. I always flush in the face and ears with it but otherwise no issues. It was given to me prior to my cesarean section for my son but the doctor upped my fluid IV causing dangerously low sodium levels but it was quickly adjusted and no harm done in the long term."
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"I have mild hemophilia type A. My factor eight level is about 8-9%. Once infused, my factor eight level usually increases to over 40%. Good for oral dental surgeries such as extraction or even implants. Side effects are pretty pronounced. Face flush, blood pressure rise. Both of these effects subsided gradually. Peak factor increase occurs 20-40 minutes after infusion. Half-life is approximately 3-4 hours, so any dental surgery needs to be timed. Secondly, an anti-fibrinogen is also taken so coagulation clots dissipate slowly. It all works for dental surgery but requires a lot of coordination with the dentist, hematologist, and infusion center. The infusion center needs to plan in advance of infusion as DDAVP drip infusion takes time to prepare. You want to aim for surgery to begin at most 1-2 hours after infusion. I now always talk in person with the infusion center regarding the timing aspect. DDAVP is only recommended if the hemophilia type A is classified as mild."