Rytary User Reviews & Ratings (Page 2)
Rytary has an average rating of 6.3 out of 10 from a total of 33 reviews on Drugs.com. 52% of reviewers reported a positive experience, while 30% reported a negative experience.
Reviews for Rytary
- CHJ...
- Taken for 6 months to 1 year
- October 23, 2024
For Parkinson's Disease "Was taking C/L 25/100 every 1.5 hr plus dopamine agonist. Doc was concerned about the high dose of agonist triggering compulsive behavior. Ramped down the agonist over multiple weeks and switched from C/L to Rytary 48/195; max of 2, six times/day. 'Kick start' the day with a C/L and orange juice at 7 am, then -- two R195s at 7:30; 10:30 and 1:30, dropping to one R195 at 4:30 and 7:30 pm. Appears to be sensitive to what I eat (and timing of snacks/meals). Cost of R195 appears to vary from $1 to $10/pill. Initially, tried an online pharmacy - not reliable - wouldn't provide order status or track delivery. After a couple of tries, local supermarket pharmacy has consistently delivered 360 R195s for $370. Supposed to be generic next summer."
- Ryt...
- Taken for 2 to 5 years
- September 18, 2023
For Parkinson's Disease "I was diagnosed with young-onset Parkinson's disease 4 years ago. I switched from carbidopa/levodopa after a few weeks. I'm on 61.25-245 mg four times a day, but it wears off after about 4.5 hours. I didn't know the side effects until my mom's doctor asked if she had compulsive behavior (she also has PD) on it. My dad immediately thought of me. I spent thousands compulsive shopping. I'm more than $20K in credit card debt (none before). Tried increasing the dose for tremors and pain, but got serious dyskinesia. I'm on amantadine too, and my legs have mottled spots all over, and I'm swollen everywhere. Vivid dreams and nightmares, sudden extreme fatigue. I'm not sure what's caused by the PD and what's the drugs to treat it. It does help with the overall symptoms of Parkinson's, but I still get Botox injections in my feet every three weeks for spasms."
Frequently asked questions
- Is Rytary better than Sinemet?
- What is the difference between carbidopa, levodopa, and Rytary?
- How long does it take for Rytary to start working?
- How long does Rytary stay in your system?
- Ano...
- Taken for 2 to 5 years
- July 28, 2025
For Parkinson's Disease "Rytary has been a game changer for me. I have not had any side effects from it, but I did have to persist for around 2 months for it to take full effect. I have consistently increased the dosage over the 3 years I have been using, and I am having very few off episodes or bad days."
- Ano...
- May 28, 2025
For Parkinson's Disease "I find that it is unpredictable. Sometimes I take the pill, and it works great, and other times it does not work at all. I also believe it wears off before it's supposed to. I took one dose this morning, and it wore off in an hour. I keep taking the medication in hopes that it will balance out with me, however, by doing so, I have more reasons to write this review. One of the concerning side effects is that if you stop taking it abruptly, your condition may worsen. It does not say whether that's permanent or temporary. I tried to wean off it, and I noticed a strange sensation in my right leg that is normally not affected."
- sha...
- Taken for 1 to 6 months
- November 30, 2020
For Parkinson's Disease "Was having uncontrollable shaking and muscle movement. Started on Rytary 95 mg two times a day. Working great for me. Have reduced shaking and overall muscle movement by about 90%."
- DOL...
- Taken for 1 to 6 months
- December 23, 2019
For Parkinson's Disease "Rytary seems to work, but I have morning nausea."
- Ano...
- Taken for 1 to 6 months
- August 14, 2025
For Parkinson's Disease "Takes 45 min to kick in. Has a weird release over a long period of time. I take it every 3 hr. Last dose is at 6 pm, but I wake up at 6 am when it finally wears off."
See also:
More about Rytary (carbidopa / levodopa)
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- Drug class: dopaminergic antiparkinsonism agents
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For Parkinson's Disease "I have been taking Rytary for about 5 years now with excellent results. It keeps me steadily controlled during the day. I don't have problems swallowing it. I am sad it will no longer be covered by my insurance plan. Generics don't seem to work as well."