Carbidopa / levodopa User Reviews & Ratings (Page 3)

• Pat
• October 2, 2010

Sinemet (carbidopa / levodopa) for Restless Legs Syndrome "I have Restless legs both at night and during the day. The Sinemet helps some at night, but doesn't last through the night. I can't take it during the day because it makes me sleepy and upsets my stomach. If I take it with food it doesn't work at all. I have a heart condition, so there are some medicines I can't take."

• KMano
• Taken for less than 1 month
• August 18, 2021

Rytary (carbidopa / levodopa) for Parkinson's Disease "My father started Rytary 48.75-195 dosage 3 pills - 4x times a day, he got worse with these medication. I personally think he was overmedicated by his doctor. He hadn't experienced dyskinesia yet and within the second day of Rytary, it was so bad we were worried he would break his teeth due to how he was tightening his jaw and grinding his teeth. He had only experienced a psychosis twice within his 10 year diagnosis, and every single day he was suffering from a psychosis; irritable, argumentative, paranoid, angry and extremely sensitive when he would talk about his past. Almost as his personality had completely changed with Rytary. I'm not sure if he will continue it because he's gotten worse mentally and emotionally, it's a lot for us, caregivers. Physically he's walking better and sleeping a tad better. I think Rytary needs to require a psychological exam before being prescribed this medication for Parkinson's."

• Harle...
• June 23, 2016

For Restless Legs Syndrome "I have had RLS since I was a child and before it had a name. I'm 66 now and have been taking the 25-100, carbidopa for 10 plus years. I started with a 1/4 table, but now up to full tablet and it's barely working. I can't imagine my life without it. After reading posts of others, I realize some of my experiences are also related, such as short term memory loss, (I was afraid I had beginning stages of Altzeimers. I have also found I can not even think about eating anything with sugar or lots of salt near bedtime. I wanted to share, since taking a full pill now, I have the most vivid and wonderful dreams. Bottom line, I couldn't imagine life without it. (Soap has NEVER worked for me)."

• BC p...
• Taken for 1 to 2 years
• February 28, 2019

For Parkinson's Disease "Sinemet for fibromyalgia. My wife suffers from PD for over two years now. She is using Sinemet 25-100, every 4 hours. Mylan as our usual manufacturer; Sun Pharma at times. She also takes 1 Sinemet ER at night. They seem to work well and help her a lot. Only one brand so far, Activis, works very poorly for my wife. Her leg function drops off significantly on this brand. My wife has also suffered greatly from Fybromyalgia for 10-15 years; throughout her entire body. We were so distracted by her PD problems, that we failed to notice, until 1-2 months later, that all of her Fibromyalgia pain had disappeared completely. What a wonderful side benefit of the Sinemet. I guess we were due for something positive to happen for a change. This was 1-1/2 yrs. ago and no return of the Fibro whatsoever. Blessings to all."

• mjbaz
• June 17, 2017

For Parkinson's Disease "Diag 2010 at 46yo. Currently on year 6-7 of taking this combination of drugs. Still doing good but have noticed more off time as the years/months go by. I know the 10 year time window of losing its effectiveness is fast approaching for me. Generics are not all created equal. You need to try every mfg for a few months to see which one works for you. For me the only brand that works is mfg by Mayne Pharma (formerly Teva). The other mfg: on one I can never get stabalized (to much/too little in a pill) the other one gives me night terrors."

• Karen...
• August 30, 2015

Sinemet (carbidopa / levodopa) for Restless Legs Syndrome "I have been using carbi now for several years and it is a great drug. But I have a problem in the summers. When it gets hot I start getting High Uric acid (gout). I would like to know if any one else has this problem. And if so what did you do. What did your Dr do? "

• Rytary
• Taken for 2 to 5 years
• September 18, 2023

Rytary (carbidopa / levodopa) for Parkinson's Disease "I was diagnosed with young-onset Parkinson's disease 4 years ago. I switched from carbidopa/levodopa after a few weeks. I'm on 61.25-245 mg four times a day, but it wears off after about 4.5 hours. I didn't know the side effects until my mom's doctor asked if she had compulsive behavior (she also has PD) on it. My dad immediately thought of me. I spent thousands compulsive shopping. I'm more than $20K in credit card debt (none before). Tried increasing the dose for tremors and pain, but got serious dyskinesia. I'm on amantadine too, and my legs have mottled spots all over, and I'm swollen everywhere. Vivid dreams and nightmares, sudden extreme fatigue. I'm not sure what's caused by the PD and what's the drugs to treat it. It does help with the overall symptoms of Parkinson's, but I still get Botox injections in my feet every three weeks for spasms."

• Robert
• Taken for 2 to 5 years
• December 16, 2021

Sinemet (carbidopa / levodopa) for Parkinson's Disease "I have been on Sinemet 12.5/50mg taken 4 times a day, for 22 months, but now my tremor seems to be getting worse, I have now started taken 5 pills a day but this only makes the tremors worse. and my lower jaw tremors. Advise anyone?"

• ctpritc
• Taken for 6 months to 1 year
• June 21, 2019

For Restless Legs Syndrome "I've been taking Ropinirole for RLS for several years, and it has worked well. Last year I started taking Sinemet 25/100 five times a day for Parkinson's, and, without knowing Sinemet was a treatment for RLS, I noticed that even if I didn't take Ropinirole some nights, I still didn't get restless legs. I started wondering if Sinemet was a treatment for RLS and just found out it is, although it doesn't work 100% of the time on its own."

• brig
• May 24, 2020

For Parkinson's Disease "I am currently 60 years old, and have had juvenile Onset Parkinson's since back in 1975. I started taking Carbidopa/Levodopa 25/100mg (instant release) 3X/day. Over the next 35 years, that dose slowly increased until I was taking around a massive dose a day , with significant off times. I also had debilitating dyskinesia, dystonia, and falls. So in the late 2000's my Neuro told me it was time to consider options. Like Deep brain stimulation (DBS)? So I gave in and had Bilateral subthalamic nucleus (STN) DBS. WOW! Yes, I have some newer speech issues. and more of a fall hazard than before. But, the old me was BACK, feeling great. I was able to cut my meds back down to 400mg of Carbidopa/Levodopa extended release per day. Today? I'm up to 800mg of Carbidopa/Levodopa extended release per day, plus 274mg of extended release Amantidine (Gocovri) but my DBS keeps my off times to an absolute minimum. I still have issues with Dyskinesia, Dystonia, and get a few hallucinations late at night from my Amantidine."

• shrip
• Taken for 2 to 5 years
• February 12, 2020

For Parkinson's Disease "I've been on carbidopa/levodopa/dopamine for two years after being on Rasagaline /Azilect. I hate carbidopa/levodopa. I am always nauseated , I have gained weight I can't think and I am very depressed. I have told my neurologist this and the answer is well let's try adjusting the dosage. I have night sweats, nightmares and am always tired. Help"

• Jo Bob
• Taken for 1 to 2 years
• November 22, 2019

For Parkinson's Disease "I have been taking Sinemet for nearly two years. I do not have a tremor. The drug helps relieve muscle stiffness and pain and helps my balance somewhat. However, it does nothing to help my slow movements and weakness, my speech, insomnia, etc."

• PIEVANS
• February 8, 2018

For Restless Legs Syndrome "I've taken Sinemet for 15 years now for RLS. I've experienced no side effects. I actually take Mirapex at night which works well but find it wears off by the next afternoon. I take the Sinemet around lunchtime in order to carry me over until I take the Mirapex in the evening. The timing and combo work very well."

• da mutt
• Taken for 10 years or more
• May 6, 2020

For Restless Legs Syndrome "In 2001, I was diagnosed with RLS while participating in an overnight Sleep Lab to determine if I had Sleep Apnea. Good News / Bad News: No Sleep Apnea / YES to RLS. My doctor prescribed carbidopa/levodopa 25mg tablets 1 to 3 tablets every night before going to bed. It's worked every night (I take 75 mg) and I've never had one issue with RLS. In 2011, I returned to the Sleep Lab and this time they discovered a mild case of Sleep apneoa, prescribed a CPAP machine, but did not find a trace of RLS . My wife could not be happier: NO more RLS and NO more snoring."

• Pregn...
• July 7, 2017

Sinemet (carbidopa / levodopa) for Restless Legs Syndrome "I am going on my 5th pregnancy with boy number 5. Around 9 weeks my legs were flopping around like a half-dead fish out of water that is what my legs looked like about every 30-40 seconds all day and night unless I was walking constantly. I begged my doctor to give me something, anything. She refused. I tried every natural remedy I could think of. She finally gave me sinomet at 25/100 mg dose half a pill and it worked wonders but I noticed after a few weeks of taking it wore off faster and then my legs became worse so my doctor has to keep increasing my dosage. I am 30 weeks now and at 2 pills a day. I take in half and quarter increments throughout the day to avoid the onset of the RLS. if taken properly it works great."

• Anonymous
• Taken for 2 to 5 years
• April 18, 2023

Sinemet (carbidopa / levodopa) for Restless Legs Syndrome "I have suffered with RLS for many years off and on and I was initially put on Sinemet and it really helps. Later on I had a very bad episode of RLS and they tried me on one of the newer RLS meds and it gave me bad GI upset so I went back on my Simemet and Gabapentin. Sinemet has always helped my RLS and I highly recommend it!"

• Horri...
• Taken for 1 to 6 months
• March 1, 2023

For Parkinson's Disease "My husband was on Carbidopa/Levodopa for about 3 months. Last month he experienced anger, depression, and much confusion. This has set him back. He was taken off this medication and I am unsure if he will get back to where he was before starting this medication—terrible experience."

• Nance
• Taken for 6 months to 1 year
• March 7, 2022

For Parkinson's Disease "Just started this treatment. I don't know if I need to take more because about 30 mins before time to take next dose my symptoms are back. I feel nauseous and don't know why. I does help my gait and not being able to talk so people can understand me..."

• Reagan
• July 15, 2021

Sinemet (carbidopa / levodopa) for Restless Legs Syndrome "I have bad RLS. Have been prescribed 100 mg sinemet once a day. I have been told not to take more than one in a 24 hr period. But it doesn’t get me thru the night of sleep. Worries to take more because I’ve been told not to. Any suggestions would be appreciated. Maybe take half at bed and the other half when it wakes me up and wears off?"

• wv_pi...
• September 4, 2009

Sinemet (carbidopa / levodopa) for Parkinson's Disease "Overall was an effective drug for me, but had problems with it wearing off between doses."

• Anonymous
• August 20, 2010

Sinemet (carbidopa / levodopa) for Restless Legs Syndrome "Sinemet works great for my restless legs syndrome, even better than the drugs more popularly prescribed. It is absolutely the one medication I cannot live without!"

• Anony...
• Taken for 1 to 6 months
• April 29, 2018

Sinemet (carbidopa / levodopa) for Parkinson's Disease "I took Sinemet for about a month, and while it lessened my uncoordinated hand movement, I fell into a very deep depression, and was having panic attacks. As soon as I stopped taking it, I was better."

• Anonymous
• May 15, 2011

Sinemet (carbidopa / levodopa) for Restless Legs Syndrome "It is working great for me and unlike other medications it is not a controlled drug nor addicting."

• mark...
• June 5, 2017

Sinemet (carbidopa / levodopa) for Parkinson's Disease "terrible depression, mood swings, not helping tremors seems same as before I was taking them, might ask doctor to stop giving it one more week, I have been taking for 6 weeks"

• lizzann
• Taken for 6 months to 1 year
• October 19, 2015

Sinemet (carbidopa / levodopa) for Restless Legs Syndrome "I have to take more and more. It wears off fast. I also get constipated and itch like crazy from it!"