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Chronic Myeloid Leukemia


Chronic myeloid leukemia (CML) is also called chronic myelogenous leukemia. It is cancer of the bone marrow and blood cells. With CML, blood cells that should become white blood cells (WBCs) do not fully grow. These cells do not fight infection like a normal WBC should. They crowd the bone marrow and prevent normal blood cells from growing and fighting infection.


Informed consent

is a legal document that explains the tests, treatments, or procedures that you may need. Informed consent means you understand what will be done and can make decisions about what you want. You give your permission when you sign the consent form. You can have someone sign this form for you if you are not able to sign it. You have the right to understand your medical care in words you know. Before you sign the consent form, understand the risks and benefits of what will be done. Make sure all your questions are answered.

Drinking liquids:

Men 19 years old and older should drink about three Liters of liquid each day (about 13 eight-ounce cups). Women 19 years old and older should drink about two Liters of liquid each day (about 9 eight-ounce cups). It is especially important to drink enough liquids if you are vomiting (throwing up) from chemotherapy. Follow your caregiver's advice if you must change the amount of liquids you drink. For most people, healthy liquids to drink are water, juices, and milk. If you are used to drinking liquids that contain caffeine, such as coffee, these can also be counted in your daily liquid amount. Try to drink enough liquid each day, and not just when you feel thirsty. It may be helpful to drink liquids between your meals instead of with your meals.

Heart monitor:

This is also called an ECG or EKG. Sticky pads placed on your skin record your heart's electrical activity.

A pulse oximeter

is a device that measures the amount of oxygen in your blood. A cord with a clip or sticky strip is placed on your finger, ear, or toe. The other end of the cord is hooked to a machine.

Reverse isolation:

You may be put on reverse isolation safety measures if your body is having a hard time fighting infections. You are given a private room to protect you from other people's germs. Caregivers and visitors may wear gloves, a face mask, or a gown to keep their germs away from you. Everyone should wash their hands when entering and leaving your room.


You may be given medicines to treat problems caused by your CML. For example, you may be given antibiotics or other medicines to help your body fight infection. You may be given fever or pain medicine. You may take medicines to help you cope with chemotherapy side effects such as upset stomach or diarrhea.


  • Blood tests are used to count the number of each type of blood cell (RBCs, WBCs, platelets). The tests may also show the phase of CML that you have.
  • Bone marrow biopsy: This is when a sample of bone marrow is removed and sent to a lab for tests. Bone marrow is the soft, spongy tissue inside the bone. The skin over your upper hipbone is first cleaned. Caregivers put numbing medicine into your skin so you will have little pain. A bandage is put on the biopsy area after the tissue sample is taken.


  • Blood transfusion: You will get whole or parts of blood through an IV during a transfusion. Blood is tested for diseases, such as hepatitis and HIV, to be sure it is safe.
  • Medicines may be given to decrease the growth of CML cells and increase the growth of normal blood cells.
  • Chemotherapy is used to kill cancer cells before a bone marrow stem cell transplant.
  • A transplant is rarely used to replace your bone marrow or to give you stem cells. Stem cells are the part of the bone marrow that make or change into blood cells. The stem cells go into your bone marrow and become blood cells.

Venous access device:

An IV catheter or tube may be placed in a large vein (blood vessel) near your collarbone, in your neck, or in your arm. Some examples of these venous access devices are Hickman. Groshong, and PICC lines. You may also have a port, which is a type of venous access device that is placed under the skin and connected to a large vein. You may need a venous access device to receive chemotherapy, other medicines and fluids that need to be given through a big vein. A venous access device can stay in longer than a regular IV can. You may need this device to receive chemotherapy treatments.


  • Chemotherapy and medicines used to treat CML may cause side effects such as nausea, vomiting, and diarrhea. You may feel very tired and have extra body fluid. You could have a bad reaction to a bone marrow transplant or stem cell transplant. You may get a blood clot in your leg or arm. This can cause pain and swelling, and it can stop blood from flowing where it needs to go in your body. The blood clot can break loose and travel to your lungs or brain. A blood clot in your lungs can cause chest pain and trouble breathing. A blood clot in your brain can cause a stroke. These problems can be life-threatening.
  • Treatment of CML may be slow to work, or may not work at all. CML may not go away or it may get worse. If your CML goes into remission, it may return. CML may also spread to other parts of your body. If you do not have treatment, or the treatment does not work, you could die.


You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your caregivers to decide what care you want to receive. You always have the right to refuse treatment.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Learn more about Chronic Myeloid Leukemia (Inpatient Care)

Associated drugs

Micromedex® Care Notes