The originating document has been archived. We cannot confirm the completeness, accuracy and currency of the content.
Generic Name: alpha-1 proteinase inhibitor (human) (AL-fa PROE-teen-ase in-HIB-i-ter)
Brand Name: Examples include Aralast NP and Zemaira
Zemaira is used for:
Treating emphysema caused by alpha-1 proteinase inhibitor deficiency (also known as alpha-1 antitrypsin deficiency).
Zemaira is an alpha-1 protease inhibitor. It works by blocking substances in the lungs that break down lung tissue and sometimes causes emphysema.
Do NOT use Zemaira if:
- you are allergic to any ingredient in Zemaira
- you have an immunoglobulin A (IgA) deficiency and have antibodies against IgA
Contact your doctor or health care provider right away if any of these apply to you.
Before using Zemaira:
Some medical conditions may interact with Zemaira. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have heart or circulatory problems
Some MEDICINES MAY INTERACT with Zemaira. However, no specific interactions with Zemaira are known at this time.
Ask your health care provider if Zemaira may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Zemaira:
Use Zemaira as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Zemaira is administered as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
- Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
- Do not miss any doses. If you miss a dose of Zemaira, contact your doctor.
Ask your health care provider any questions you may have about how to use Zemaira.
Important safety information:
- Tell your doctor or dentist that you take Zemaira before you receive any medical or dental care, emergency care, or surgery.
- Zemaira contains albumin, which comes from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products with albumin. No cases of these problems have been found in patients who have used Zemaira.
- PREGNANCY and BREAST-FEEDING: It is not known if Zemaira can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Zemaira while you are pregnant. It is not known if Zemaira is excreted in breast milk. If you are or will be breast-feeding while you use Zemaira, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Zemaira:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; headache; muscle pain; nausea; pain, bruising, swelling, or redness at the injection site; runny nose.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fainting; severe or persistent dizziness; shortness of breath or wheezing; swelling of the ankles or feet; symptoms of infection (eg, fever, chills, muscle aches, sore throat); tingling or numbness of the skin; weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Zemaira:
Zemaira is handled and stored by a health care provider. You will not store it at home. Keep all medicines, as well as needles and syringes, out of the reach of children and away from pets.
- If you have any questions about Zemaira, please talk with your doctor, pharmacist, or other health care provider.
- Zemaira is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Zemaira or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Zemaira. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Zemaira. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Zemaira.