Medically reviewed on July 4, 2018
Uses of Silvadene:
- It is used to avoid or treat skin infections in patients with burns.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Silvadene?
For all patients taking Silvadene (silver sulfadiazine):
- If you have an allergy to silver sulfadiazine or any other part of Silvadene (silver sulfadiazine).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are pregnant and near term.
- If you are breast-feeding or plan to breast-feed.
- If your child is a premature baby or is a newborn. Do not give Silvadene (silver sulfadiazine) to a premature baby or a newborn.
- If your child is younger than 2 months of age. Do not give Silvadene (silver sulfadiazine) to an infant younger than 2 months of age.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Silvadene (silver sulfadiazine) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Silvadene?
- Tell all of your health care providers that you take Silvadene (silver sulfadiazine). This includes your doctors, nurses, pharmacists, and dentists.
- If you have a sulfa (sulfonamide) allergy, talk with your doctor.
- Be careful if you have G6PD deficiency. Anemia may happen.
- You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
- Do not use longer than you have been told. A second infection may happen.
- This medicine may cause harm if swallowed. If Silvadene (silver sulfadiazine) is swallowed, call a doctor or poison control center right away.
- This medicine may affect certain lab tests. Be sure your doctor and lab workers know you use Silvadene (silver sulfadiazine).
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Silvadene (silver sulfadiazine) while you are pregnant.
How is this medicine (Silvadene) best taken?
Use Silvadene (silver sulfadiazine) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Do not take Silvadene (silver sulfadiazine) by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
- Use as you have been told, even if your signs get better.
- Wash your hands before and after use. Do not wash your hands after use if putting this on your hand.
- Wear special gloves while putting Silvadene (silver sulfadiazine) on.
- Clean affected part and take off dead skin.
- Put a thin layer on the affected part and rub in gently.
- Put on 1 or 2 times a day or as you have been told by the doctor.
- Use a dressing if needed.
What do I do if I miss a dose?
- Put on a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not put on 2 doses or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Blood in the urine.
- Not able to pass urine.
- Any unexplained bruising or bleeding.
- Feeling very tired or weak.
- Very bad belly pain.
- Very bad skin irritation.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
What are some other side effects of Silvadene?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Change in color of skin.
- Skin irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Silvadene?
- Store at room temperature.
- Protect from heat.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Silvadene (silver sulfadiazine), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Silvadene (silver sulfadiazine topical)
- Silvadene Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 5 Reviews
- Generic Availability
- Drug class: topical antibiotics