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Prohance

Generic Name: Gadoteridol (gad oh TER i dol)
Brand Name: Prohance

Medically reviewed on May 2, 2018

Warning

  • This medicine raises the chance of a health problem called nephrogenic systemic fibrosis (NSF) in some people. This may lead to very bad and sometimes deadly skin, muscle, and organ problems. Call your doctor right away if you have skin burning, itching, swelling, or scaling; red or dark spots on the skin; or hard or tight skin. Call your doctor right away if you have stiff joints, muscle weakness, or hip or rib pain. Call your doctor right away if you have trouble moving, bending, or straightening your arms, hands, legs, or feet.
  • Before using Prohance (gadoteridol), talk with your doctor if you have any of these health problems: High blood pressure, high blood sugar (diabetes), kidney disease, or liver disease. Tell your doctor if you have recently taken a drug like this one.
  • If you are 60 or older, use Prohance (gadoteridol) with care. You could have more side effects.
  • Your blood work may need to be checked. Talk with your doctor.

Uses of Prohance:

  • It is used during an MRI (magnetic resonance imaging) test.

What do I need to tell my doctor BEFORE I take Prohance?

  • If you have an allergy to gadoteridol or any other part of Prohance (gadoteridol).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Prohance (gadoteridol) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Prohance?

  • Tell all of your health care providers that you take Prohance (gadoteridol). This includes your doctors, nurses, pharmacists, and dentists.
  • Tell your doctor if you have had a drug like this one before. This medicine has a heavy metal called gadolinium in it. Gadolinium can stay in parts of the body for months to years after getting Prohance (gadoteridol). This has not been shown to be harmful in people with normal kidneys. However, some people may be at higher risk. If you have questions, talk with your doctor.
  • Very bad and sometimes deadly allergic reactions have rarely happened. Talk with your doctor.
  • Kidney failure has happened with Prohance (gadoteridol) in people who already had kidney problems. Talk with the doctor.
  • Use with care in children. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Prohance (gadoteridol) while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Prohance) best taken?

Use Prohance (gadoteridol) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as a shot into a vein.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.

What are some other side effects of Prohance?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Prohance?

  • If you need to store Prohance (gadoteridol) at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Prohance (gadoteridol) is refilled. If you have any questions about Prohance (gadoteridol), please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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