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Necitumumab

Generic Name: Necitumumab (ne si TOOM oo mab)
Brand Name: Portrazza

Medically reviewed on Sep 5, 2018

Warning

  • Rarely, very bad heart problems and sudden death have happened in people treated with necitumumab along with gemcitabine and cisplatin. Talk with the doctor.
  • Low magnesium levels have happened with necitumumab. Sometimes, people have had very low magnesium levels. Talk with the doctor.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.

Uses of Necitumumab:

See also: Alunbrig
  • It is used to treat lung cancer.

What do I need to tell my doctor BEFORE I take Necitumumab?

  • If you have an allergy to necitumumab or any part of necitumumab.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are breast-feeding. Do not breast-feed while you take necitumumab or for 3 months after your last dose.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take necitumumab with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Necitumumab?

  • Tell all of your health care providers that you take necitumumab. This includes your doctors, nurses, pharmacists, and dentists.
  • This medicine may raise the chance of very bad and sometimes deadly blood clots like heart attack. The chance may be higher in people who have ever had a blood clot. Talk with your doctor.
  • It is common for skin reactions to happen with necitumumab. These reactions may include acne, dry or cracked skin, itching, rash, redness, or other skin irritation. Most of the time, skin reactions happened within 2 weeks of starting necitumumab and went away within 17 weeks after. Call your doctor if you have a skin reaction that is very bad, bothers you, or does not go away.
  • Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
  • Infusion reactions have happened with necitumumab. Sometimes, these could be very bad or life-threatening. Talk with the doctor.
  • If you are 70 years or older, use necitumumab with care. You could have more side effects.
  • This medicine may cause harm to the unborn baby if you take it while you are pregnant.
  • Use birth control that you can trust to prevent pregnancy while taking necitumumab and for 3 months after care ends.
  • If you get pregnant while taking necitumumab or within 3 months after your last dose, call your doctor right away.

How is this medicine (Necitumumab) best taken?

Use necitumumab as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as an infusion into a vein over a period of time.
  • Other drugs may be given to help with infusion side effects.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
  • Very bad dizziness or passing out.
  • Change in nails.
  • Fever or chills.
  • Change in eyesight, eye pain, or very bad eye irritation.
  • Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.

What are some other side effects of Necitumumab?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Necitumumab?

  • If you need to store necitumumab at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about necitumumab, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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