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Cholbam

Generic Name: cholic acid (KOE-lik AS-id)
Brand Name: Cholbam

Cholbam is used for:

Treating certain bile acid problems caused by single enzyme defects (SEDs). It is also used to treat peroxisomal disorders like Zellweger spectrum disorders.

Cholbam is a bile acid made in the liver. It works by helping digest fat and absorb certain vitamins in the bowels.

Do NOT use Cholbam if:

  • you are allergic to any ingredient in Cholbam

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cholbam:

Some medical conditions may interact with Cholbam. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver problems
  • if you or a family member has high blood triglycerides

Some MEDICINES MAY INTERACT with Cholbam. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Cyclosporine because it may increase the risk of Cholbam's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cholbam may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cholbam:

Use Cholbam as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Cholbam by mouth with food.
  • Swallow Cholbam whole. Do not break, crush, or chew before swallowing.
  • If you cannot swallow the capsule whole, you may open the capsule and mix the contents with certain foods. For younger children, the contents may be mixed with infant formula or breast milk. For older children and adults, the contents may be mixed with soft food (eg, mashed potatoes, apple puree). Stir for 30 seconds and swallow right away. Do not store for future use.
  • If you also take cholestyramine, colesevelam, colestipol, or an antacid with aluminum in it, do not take them within 4 to 6 hours before or 1 hour after taking Cholbam. Check with your doctor if you have questions.
  • If you miss a dose of Cholbam, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Cholbam.

Important safety information:

  • Tell your doctor or dentist that you take Cholbam before you receive any medical or dental care, emergency care, or surgery.
  • The dose of Cholbam may need to be changed as your child's weight changes. Have your child's weight checked often. Talk with the doctor before changing your child's dose.
  • Lab tests may be performed while you use Cholbam. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cholbam while you are pregnant. Cholbam is found in breast-milk. If you are or will be breast-feeding while you use Cholbam, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Cholbam:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); symptoms of new or worsening liver problems (eg, dark urine, pale stools, persistent loss of appetite, right-sided stomach pain, unusual bruising or bleeding, unusual nausea or tiredness, yellowing of the skin or eyes).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Cholbam:

Store Cholbam at room temperature, between 69 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cholbam out of the reach of children and away from pets.

General information:

  • If you have any questions about Cholbam, please talk with your doctor, pharmacist, or other health care provider.
  • Cholbam is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Cholbam or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Cholbam. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Cholbam. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Cholbam.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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