When is the best time to take Zoloft?

When its prescribed might be a good idea

I have been on Zoloft for 4 weeks today. 2 weeks at 25mg, and 2weeks at 50mg. I am taking it for anxiety and depression associated with divorce. I have been taking Zoloft in the mornings, and I am noticing a definite daily cycle. I feel very anxious, sleepy, tremors etc in the morning but by the afternoon I am feeling more calm and composed. My doctor has suggested splitting the dose 25mg morning, and 25mg in the evening, and if that doesn't work try a higher dose. I am yet to try this but it might be an option for others.

I had the same problem and just switched to evening and it really helped. My doctor said it was better in the morning, but not for me.

If the Zoloft is causing you to feel that way, it is perfectly fine to take it in the evening. Actually, as long as you take it around the same time every day to keep a constant bloodlevel, you will be ensuring that the medication is doing it's best for you.

I have not started my zoloft meds yet and I'm super nervous about it. But I'm definitely going to give it a try. I was told by the pharmacist it could make me sleepy at first but then it could change within a few weeks or so to make it hard to sleep. And to start it on my weekend so if I am sleepy I can rest without having to be up early. And that I should prob start it at night but may have to switch it later on to morning if it starts keeping me from sleeping. He said you will know yourself because everyone is different.

I just started Zoloft approximately a week ago. After getting off Effexor. My Dr prescribed 50mg to take in the morning. All I do is sleep the day away watching Netflix. I want to do my usual activities like go the gym. Also need to be motivated and the energy to shower daily. But, I'm just too darn tired! I'm definately switching to nights despite the crazy dreams. I took the anti depressants to get me out of this horrible depression and to get me going not lay around like a cow in pasture. I will give this some time. Hopefully I will see some improvement with my moods.

Ya know ... I took a diet pill and felt like a million dollars, mood lifted, energy etc., I don't know why it has this effect but I sure wish they would put a little of this in my anti depressant...

Take it one per day and the dosage will work better at night before sleep as is the case with most pills.

I take mine right before bed. Then its not so bad if it makes me dopey.

I just called my pharmacist and ask him about the best time to take Zoloft. I have been taking it in the am and the bottle said to take at bedtime. I had not noticed that on the bottle before. She said, whatever I was comfortable with. Some take it at night if it makes them sleepy. I don't get sleepy with it, so I am going to continue taking it in the am. So, I guess it works diff with everyone. I, too, have trouble sleeping. I have a sleep aid for night.

My husband takes Zolaft for bipoar depression, & always took it in the morning. After reading on thi site about all the problems people were having with it making them sleepy I talked him into taking it at bedtime. Now he is sleeping better, & more awake in the day as it should be, so good suggestions guys & gals...

I would recommend taking it at night. I was taking it in the morning and I was so tired I passed out in all of my classes and I felt sick to my stomach. At night I don't feel anything

I was just put on zoloft within the moth and both my doc and pharmasist agree that YOU take it when you are comfortable takeing it.everyone reacts differently... so if your body gets tired after takeing it in the morning try at night time like others said... just make sure whenever you take it be consistant. If you stillhave problems in a few weeks talk to your doc about trying a different SSRI that may have a different reaction with you,. Only thing is you have to give yourself and body a couple of weeks to get adjusted.
~a friend

Hello dbrennan! I take Zoloft in the am but it does not make me sleepy. Nothing seems to make me sleepy! I wish there was something out there. You can also take Zoloft in the evening before bedtime if you prefer. If you have just started on Zoloft the sedation should go away in a week or so. I wish you the best! Sweetie Pie

Unless you have been told differently by your doctor maybe trying to take this in the evening or before you go to bed it might allow you to rest throughout the night and then work in your system throughout the day, anyway it something that you could try and if it doesn't work you could always change back. I do hope these effects either work better by you adjusting the time you take it or it may be such a thing that as time goes on your body will adjust to these side effects, I wish you the very best of luck!