When is the best time to take Zoloft?

Hello dbrennan. No need to comment or answer this, I was on zoloft some time ago. and as Delila, said, most often, in regards to our meds, its simply what you're most comfortable with, you know time of day, schedules and so forth. I took mine, meaning zoloft, in the morning. It was troublesome to take at night because more often than not, kept me up at night. I'm an insomniac. I also felt tired, more fatique, and that was why I stopped it. Otherwise, it was a comfortable drug to be on. The side effects are generally minimal. I know that the half-life, in zoloft is fairly quick. Well, went on a bit, ha! Just thought to share that. Best of wishes to you.

Hi, to some extent the time of day you take a/d drugs is down to personal preference. Try taking it at night and see how you feel. I take 2 different anti-depressants, one in the morning and one in the evening before bed as that one makes me sleepy. Give it a go for a few days/a week. How long have you been on the zoloft?