This is the second time I've been on an SSRI and had problems with it. Anyway, I am going to see my family physician Monday because of the problems with my Prozac and she's not my Subs doc. I need to go ahead and get the new med started ASAP for it to help with my PMDD before it starts next month and can't get in to the sub doc until the 20th. I don't know how much she knows about subs, so I need some ideas to be looking into before my appt. Monday. Please excuse me if my phone does anything stupid here.
What antidepressants are safe to take with Suboxone?
Question posted by linda0982000 on 10 July 2011
Last updated on 8 May 2014
If at all possible, some inexpensive examples would be great. I'm self pay and the Subs alone is really taking a toll on the finances.
If your depression is situational, and medicine can't cure situational depression, why are you taking medicine?
As far as I know, any of the AD meds are safe with Sub. Except maybe those MAOI antidepressants, but they have a whole slew of problems. I think the rule of thumb when mixing Sub with anything is to think of Sub as an opiate, because that's what it is. It's a unique opiate, but that's what it boils down to. So if something is unsafe with opiates, it's probably not safe with Sub, and if it is safe with opiates, then it should be safe with Sub. There's a lot of mystery surrounding Sub, and sometimes I get annoyed over that. I can see where that once served a purpose, but now I think it's plain dumb. So you should tell your doc you're on Sub, and the doc should know what's safe and what isn't. I think probably the doses would have to be adjusted with Sub, as they would with any opiates.
I personally have mixed the following AD meds with Sub. Wellbutrin, which I take most often. Trazodone, which I use occasionally for sleep. And I was on Cymbalta for 1 whole year due to a very severe depression. And the doc who gave me the Cymbalta is today the doc who gives me the Sub.
Depression is a really terrible thing. I've had it since I was 6 years old. I actually think it's part of this whole addiction disease. I'm also familiar with a situational depression. I think a large part of mine is situational. I'm not sure any drugs are all that effective against a situational depression. What's worse, I think if a situational depression goes on long enough, that it then causes a chemical depression. I don't know if I'm right about this, but if I am then that's the rationale for taking an AD med. This is a difficult situation, and that's why you need a good experienced doc handling it.
I wish you the best.
I'm hesitating recommending any SSRI or similar antidepressant or tricyclic antidepressant because of the possible interaction. The warning is that the use of an antidepressant with Suboxone lowers the seizure threshold thereby increasing the chances of having one. That being said, if you are not prone to seizures for any reason and the doctor starts you out on the lowest end of the dosage range, you should be ok. I recommend the following options which come in generic and should be affordable:
Wellbutrin which the generic is bupropion
Celexa which is citalopram
Effexor which is venlafaxine
Lexapro which is escitalopram
For a complete list of options for PMDD you can go to:
You will notice most of the choices are for bupropion and that several of the
choices are for contraceptive class drugs. Have you tried different birth control pills to help with this problem?
Hope some of this helps,
amitriptyline is safe and cheap to take with subs. I am sensitive to antidepressants ,my depression is situational, and antidepressants can make me a bit manic and I am NOT bi-polar. Make sure you are not on the extended release Prozac, just the plain Prozac (fluoxetine) the ER formula makes me panic, 10mgs of the regular and I am fine. That might be the problem, the ER formula. Amitriptyline is generic of Elavil. Best of luck, and yes my subs dr knew I took 25 mgs of amitriptyline when he augmented with fluoxetine 10 mgs as I went into a severe form of depression when I first got on subs called anhedonia, which means I felt no pleasure at all, like a blank TV screen. I took 10 mgs 'zac one day and 25 mgs of Ami the next, but it worked for me. You might ask for 10 mg pills of Ami but ask if they will right the rx so you can go up to 20 mgs of Ami if you need it. Best of luck, this helped me. Patti
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