Hello, I'm gaining weight on this medication and have not changed my diet at all, does anyone else have this problem? Thank You
Viibryd - does this cause weight gain?
Question posted by ScrubJay on 24 Oct 2011
Last updated on 21 December 2020 by WildcatVet
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
25 Answers

Weight gain is not a stated side effect of Viibryd but may be a possibility. Actually manufacturers specifically note that it does not cause weight gain. Please see link below.
As with most, if not all, psychotropic medications there is a risk of weight gain with Viibryd for a small number of people:
"Metabolic
Common (1% to 10% of users): Increased appetite, increased weight"
Metabolic changes include increased appetite and changes to fat storage mechanisms. Proper diet and exercise can help to minimize excessive weight gain but it's unavoidable in a minority of unlucky patients.
Yes on weight gain! My prescriber told me it does not make you gain weight but I have gained 35+ lbs in the few months that I have been on it! I am also craving sweets that I never crave but still eat pretty healthy. Yes, none of my clothes fit. I had to buy a new wardrobe. Exercise has done nothing. I am bloated constantly. Clearly the manufacturer lies! Also, I’m still depressed so this is a bad side affect as any. It appears to be a weight gain sugar pill.
I took Viibryd for 2 months and have gained alot of weight I always was 115 and now I'm 139! I'm so disgusted with myself... My stomach is thicker and I have never been this heavey eaven after having my two children... Plz if u are not wanting weight gain stay awayyyfrom this medicine!!! (Huge warning) I am so upset no jeans fit me anymore and it only started when I started this medicine.. I have been stopped for months and yet the weight still keeps adding! Beware!!
Yes, it did for me. I've gained 20 pounds within 6 months. It did control my depression but I can't afford the additional weight gain being a diabetic.
I started taking viibryd about 6 months ago and have gained from 138lbs to 149lbs ,. although I have tried to keep the weight off with dieting. I find my self craving food all the time. All of the weight is going to my mid-section and now I have a cottage cheese look that I have never had before and muffin tops. UGGGHHHHH I wondered if it was just my age (47) or the medication change. After reading all these posts I am convinced it is the viibryd. I will start wheaning myself off of this medicine tomorrow. Thank you to everyone that has shared your results on this site!!!
Good question. I'm lucky in that I don't eat when I'm anxious or depressed. I WAS very tiny. Although since I started on 3 different types of this medication about 6-8 months ago, I gained about 5 pounds. In the last 2 months of being on Viibryd, I have gained about 15 pounds. NONE of my clothes fit me. Am I eating more? ... how much more and why, is the question. - Perhaps because I feel better I'm eating more, but I'm not buying that... I work out, etc., and I am suddenly 'thick' in the middle, and I have only been thick there twice - with the pregnancy of my two children. - My tummy has always been flat. Even after the kids. So, I am going down to 20mg from 40mg, as someone said they did, and hope that works. THANK YOU FOR THAT BTW... But If the weight doesn't start coming off, I'm done; because weight gain is not an option for me.
'You're just feeling better and eating more"
No that's just what the doctors tell you and it's not true. No one truly knows why these drugs make you gain so they just blame you. It's easier to do that so they can scoot us out the door with another prescriptionand then go on to the next payment (patient). Have you lost any of the weight you gained since going off the medication? I haven't and it's been 4 months. Crazy side effect.
I had been on Wellbutrin and Prozac for 11 years (Prozac first, then added the Wellbutrin) and found it very affective other than the sexual side effects. Decided with my doctor to try Viibryd to address those. Unfortunately, with no change in eating habits, I've gained 10 pounds in three months. I haven't seen any huge improvement with the sexual issues either :(
I have an appointment to try something else. Thinking about going back to the Wellbutrin and finding something to replace the Prozac ( or maybe try Wellbutin alone to see how that goes). Anyone feel successful with just Wellbutrin?
I have read a lot of reviews from different sites and yes we are all different and are different ages... But for one thing diarrhea,stomach growling, GI issues seemed to be a 90% problem... I was on pain meds for back problems is why i didnt have diarrhea at first. We all know pain med cause constipation but when i stopped it the diarrhea appeared and when they put me up to 40mg it was totally explosive starting at 4am several x during the day.That right there is not safe. We are losing important nutrients and dehydrating ourselves. I did crave sweets and gained 5lbs in the short time of 3 months till I realized this was the scariest thing I have ever endured... I am not computer savvy so after I had almost all the side effects and doctor said noone has reported them. I felt I was losing my mind (seriously) so i was told to google or ask .com drug reviews.com mayo clinic and several other and TADA!!!
There it all was the symptoms I was having, I was not crazy at all, it is this drug... I have been on lexapro which worked great I was going through the change and then I tried to quit and couldn't and of course I was put on pristiq didnt work but 4 mths Then Effexor XR which helped 8 mths and never ever had these side effects till this EVIL DRUG VIIBRYD... Was introduced... I started sept-2012 and have decided to get off it. Like i said they took me down to 20 mg end of march 2012 and was devastating, horrible,so I have decided may 8 2013 I have lowered it to 15 mg and have some itching issues. Then I will go to 10 mg... then hopefully will go every other day n then be off... I'm on buspar 30 mg and I take Xanax .5 in morning and .5 in evening to help with the withdrawal issues. i am Sleeping better no nitemares or muscle cramps ,The jittery and papaltations and the paralization in sleep has stopped thank you GOD. I am hoping this will go smoothly. I do hope all of you find your answers and yes we do not react the same but too many bad reviews are enough for me... it has eased my mind that it was not only me...
Yes I have been on Viibryd 40mg now for almost a year an while all my other issues have disappeared, I have gained a ton of weight, and I too have not changed any of my activities or diet.
I was on Cymbalta for 6 months and gained about 5 lbs. I didn't feel that much better so my doc switched me to Viibryd. I was already displeased with the weight gain because I'm 5'5" and went from 123lbs to about 128lbs.
I went from 128lbs to 138lbs within this first month on Viibryd. Similar to the comments made by others - it's all through my waist and thighs. Nothing in either my diet or daily activity has changed... I cannot fit into many of my clothes now!
I have been on a few different antidepressants in the last several years including Zoloft which I gained weight on. The past 8 to 9 months I have been on Prozac and gained 10-12 lbs. I have just switched to Viibryd because my doctor said it should not cause weight gain. I hope the doc is right. It is very frustrating to me that I need meds to keep from being depressed. They usually work well for me which I am thankful for but the weight gain is frustrating. It is like the meds make me crave food constantly.
Wow! the manufactuer lies!
I have gained weight too on Viibryd! And especially around my middle and my thighs! I think I will go back to Prozac.
Me too I gained 15 lbs in 2 months and in my mid section. I'm not taking it anymore.
Viibryd Queen checking in here. I certainly did not need a drug that would cause weight gain. initially lost around 8 lbs during the first couple months on Viibryd.. I'd say after 9 mos my total weight loss is around 11 lbs. I'm puzzled by those who say they have experienced bizarre, nearly impossible weight gain with this drug. Except in cases of significant water retention, drugs don't simply CAUSE weight gain-but eating more or unhealthfully does. I'm with RonMan. I think there must be something else going on but... each individual is different.
Best Regards to all of you.
Frenchie
Humm I never thought of water retention. But that would make since in the weight gain factor especially since none of my habits have changed. I will have to check with my doctor, as i know there is a water pill you can take to fix water retention.
This question as well as the responses are really concerning me. I just started taking Viibryd and I'm absolutely terrified of gaining more weight. Between Lexapro and Effexor, I gained 45 lbs in a year. My doctor told me that Viibryd actually promotes weight loss. I'm sure hoping she's right...
Related topics
weight, diet, viibryd, medication
Further information
- Viibryd uses and safety info
- Viibryd prescribing info & package insert (for Health Professionals)
- Side effects of Viibryd (detailed)
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