I’m trying to get pregnant. Can I still take spironolactone?
I'm trying to get pregnant. Can I still take spironolactone?
Question posted by nikulshyna on 19 Dec 2010
Last updated on 21 December 2010 by Marvell
Added 19 Dec 2010:
I’m a very healthy person. I eat carefully. I do my excesses every week, but I have problems with acnes. I usually have acnes around lips and neck. I’ve tried so many ways to: many treatments from acne .Nothing are helping me. I read that spironolactone helped many people. I want to try it. I am trying to get pregnant, so I afraid to use it. Could you please help with your suggestions?
Answers
Marvell
21 Dec 2010
Please discuss this with your doctor. The risks with spironolactone can't be ruled out.
Spironolactone has a pregnancy category C.
Potential benefits may warrant use of the drug in pregnant women despite potential risks.
Animal studies at the maximum human dose showed feminization of male fetuses during early pregnancy and indications of endocrine dysfunction in both male and female offspring during late pregnancy that persisted into adulthood. Diuretics, in general, are contraindicated in pregnancy, except when necessary in patients with cardiovascular disease, since they do not prevent or alter the course of toxemia and they may cause a decrease in placental perfusion. There are no controlled data in human pregnancy. Spironolactone is only recommended for use in pregnancy when there are no alternatives and benefit outweighs risk.
Related topics
Further information
- Spironolactone uses and safety info
- Spironolactone prescribing info & package insert (for Health Professionals)
- Side effects of Spironolactone (detailed)
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