Trintellix - How long does is take for the nausea to go away?

I cant take on an empty stomach or will get very nauseous and throw up. I have to eat food first then take 15-30 minutes later. then I am fine.

Don't live with discomfort and worry about it... TALK to your doctor or pharmacist!!!

Been on Trin for 3 years, 20 mg. once a day. I was ready to trash it the first week due to the unrelenting nausea. My doctor moved the dose to bedtime only and immediately the symptoms subsided. I usually eat a small snack w/it b4 bed and rarely have the severe nausea as long as I'm going to bed. It's a pain, but is the only Antidepressant I've ever taken that didnt affect my sex drive, erectile dysfunction and anorgasmia.

I have been taking 5mg a day for 6 months, the nausea is still just as bad as first day. If it has not made such a positive change in me I would stop. also I know this sounds weird but I woke up day one and coffee smell gaged me! so I no longer drink coffee, just cant stand the smell!

I just started Trintellix and the nausea is horrible. I read ginger helps with nausea and found an essential oil called DigestZen that is a blend of ginger and a few other oils. I take it at the same time I take Trintellix and NO NAUSEA! I do get a little reflux of peppermint and ginger from the DigestZen but that is much more manageable than the nausea. I don't represent or sell DoTerra products, I'm just letting anyone know, that is looking for a solution to the nausea, I found something that works for me and possibly for anyone who wants to try it. I ordered mine on eBay, but Amazon likely has it as well.

I’ve been taking 10mg for about 5 months - still nauseous everyday unless eat a couple of pieces of toast or about 10-15 saltines. Compazine does nothing. If it didn’t work so well otherwise I’d have stopped taking it.

Same experience. I have a cast iron stomach as well, nothing usually upsets my stomach. Been on a 5mg dose for almost a month. Nausea every morning and throughout the late afternoon and evening. Saltines and oatmeal help.
Losing weight as a consequence of the nausea.
I'm going to give it a couple more weeks and if the symptoms don't improve I have to switch to something else.
A shame as there seem to be no other side effects and it works well.

I have been on Trintellix for almost 2 weeks now and i still get really nauseous every morning. When i tried taking it with food i threw it all up so i have been taking it on an empty stomach and then eating about 2 hours later. Oatmeal seems to be the best thing to calm my tummy. I eat a little of that and im better for the rest of the day. I do seem to be having only diarrhea though which sucks. i hope that goes away soon. im just keeping Imodium in my purse for now.

I just took 10mg dose day 2 and I’m so nauseous... what does anyone take to feel better? I have diarrhea too :( I feel like I have the flu. I have never felt so
Bad taking a medication

Hi, I usually try to eat a few saltines before I take my meds. I do still feel nauseous periodically through the day. I just eat some fruit and it subsides. I hope this helps. Be blessed.

Trintellix (vortioxetine) is an antidepressant that affects chemicals in the brain that may be unbalanced. Trintellix is used to treat major depressive disorder in adults.

The most common side effects are nausea, constipation, and vomiting. Nausea is usually mild or moderate, and its frequency dose-related. Nausea generally occurs in the first week and last for about 2 weeks. It may continue in some people.
https://www.drugs.com/trintellix.html