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Simvastatin - Can I crush this drug?

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itsmetoo2 5 Feb 2010

From the UK's NHS Medicines Management Committee:

Atorvastatin - can be crushed and mixed with water though not very soluble so should be flushed well after administration to avoid blocking enteral feeding tube.

Votes: +0
fairways3319 13 Jan 2017

According to mayo clinic site, Lipitor (and I would assume atorvastatin) should not be crushed. I called Pfizer and they advised the same. I crushed one tablet of atorvastatin 20 MG and it was like prepping for a colonoscopy--severe diarrhea.

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