I'm in the process of titrating my lamictal dose up from 25mg to 100mg. I was at 50mg for 2 wks and and this week going up to 75mg. I have not felt well at all so far, just very depressed. Depressed is usually my predominant state, however it's really pretty bad and I keep waiting for a sign that this med is going to help. Has anyone here had this experience while starting lamictal? How long before improvement is noticed?
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Male, 53, family & busnessman. Diagnosed Bipolar 11/14. Mostly depressed 95%. Been thru the gamet, multiple drug cocktails, TMS., even ECT. Electr convulsive therapy. Extreme, 10 rounds. All failed... Almost 11 months total all out effort & felt like I was a chemistry project, which I was. Had been up to 400mg Lamictal. Did not work, along w/ failed tries at Seroquel, Abilify, SSRI, Zoloft, etc... Lots, waiting, trying, hanging strong... Finally tried Effexor! Anti-depressant worked! Titrated up to
Kate Yes this is pretty common with this medication Lamictal but this is almost too comon when you are first starting and adjusting the dose. And should let up some give it a few weeks from when your at the dose the doctor want you on and if you are still having problems check with the doctor.
Hi! I've been reading this forum for a few months now and have noticed that most of the people writing on it are at the begining of its treatment, on the first or second week. I have been on meds since I was 18 years old. I'm 30 now. Have been taking lexapro and carbolitium for a few years and have had a great life. About a year and a half ago, I had my first seizure. It was awful. Couldn't breath, heavy chest pain, seemed the world was colapsing. I was away on vacation and didn't know what was going on. After two days struggling, I decided to whatsapp my pdoc. He explained me what was going on and as soon as I got back, he put me on xanax for 15 days. Problem solved, life goes on. Half a year later, seizure again. And in June this year it happened again, very strong. So we decided it was time to change my medication.
I was feeling like really bad. Hopeless. Depressed. Couldn't work, had no pleasure in anything. Anyway, I started on Lamictal 25mg and Depakote 500mg and increased the dosage every 10 days. When I reached 100mg lamictal and 1500mg depakote I had the worst seizure ever. Fisical side effects were the worst, diziness, headaches, went almost blind, couldn't think, couldn't speak, was like a zoombie. Even tought about going to a hospital, because I couldn't even stand up anymore.
Got off everything, started depakote from the begining. It lasted 5 days, then had the same side effects again. I was starting to feel hopeless. Seemed that I was running out of options.
After a few days without any meds, pdoc told me to try lamictal again. During the last 45 days, I have been increasing the dosage and have now reached 100mg. I can say that, for me, it was the first time I felt better. Depression is almost gone and feel that the anxiety, is decreasing slowly. I'd say I'm 50% of what I expect to be. I have no side effects at all, memory is back, vision is good, can sleep, can eat, can do everything. I expect to get even better till new years when I'll be reaching 200mg and will stop there.
The main point here, is to cross this bridge between the moment you start taking the med and the moment it starts to work. 2 weeks ago I had the worst seizure since I started taking lamictal. The following week, bang! medicine started to work and showed up for the first time. It happens suddenly, when you least expect. Best friends during these period were a pair of tennis shoes and a hadphone. While I took walks, tried to think about good stuff and at the same time, tried to accept my condition of health, not blaming me for things that went wrong or things I wasn't being able to do as I did before. You have to cross this bridge. If you believe you'll get to the other side, crossing it will be easier. Get busy, excercise, don't lay on bed all day. That's the path you have to follow.
Sorry about my english, I'm not american.
For me, it took 10 weeks. When it kicked in, it was a night and day difference. I've read the same thing over and over again.. that it saves lives. But, I will say it again.. It is saving my life. Good luck.
50mg in the morning.
50mg in the evening.
I should add that I'm also on Wellbutrin as well.
Well I'm just like you waiting. I started 7 days ago at 25mg 14 days 25mg then I will go to 50mg then after days I go to 200mg. I feel really bad I have crazy thoughts I am depressed,irritated agitated, in top of all that I am unhappy. I took this medication when I was in Puerto Rico 4 years ago I was at 100mg and I stopped after 2 weeks and I had a seizure that left me still with side effects. My thyroid is not good neither I take medication for it also and my back is bad with cyst and deterioration of the bones.
I've now been taking lamictal for three years now. I started off with 100mg a day and after a week 200mg. I was also starting to take 3 other medications all at the same time for many other health reasons. The whole two weeks I started taking it I felt depressed, emotional, suicidal, I was gaining weight and had the worst anxiety! After a year I got to get off one medication, then after a year and a half I got to get off another! My results are a lot better then three years ago but I still get really depressed when I'm under stress. Once you've taken it for a long period of time, your body will adjust to it and it won't be as bad and you'll handle it a lot better! Even with me on two stong dosages of medicine at such a young age with a lot going on, it makes me depressed and have bad anxiety. I wish you the best for your health. (Please take this advice seriously. I was in the hospital for 12 days fighting for my life.) I seriously wish you your best!!
Ive been taking lamictal the same thing in addition to Xanax .5 mg and enlyte in the morning and I am still always so exhausted even if I get a great night sleep I'm still yawning and consistently tired all day. On top of that I feel even more depressed than normal. I feel like a lab rat. Even though I know all I have is ADD. I feel like I'm an experiment to see how it will work.
I still take notes everyday from how my poop is to how I feel through the whole day. I'm getting so sick and tired of waiting for change. I feel like I can't turn to anyone that listens they just do what they think is better for my problems that I already know I have and medications that I've taken to fix them that got me back on the right track. I know it's not an answer. I just didn't want you to feel alone and also vent some. I hope we can get some answers soon. Good luck bruv!
Hi. I have been on Lamictal for 2 years and i am on 200mg and it is working well for me. hope this helps.
I have been on it for 9 weeks tomorrow I start 200mg it hsnt worked for me yet :( good luck
We all react differently I'm learning. It may kick in as it levels up in your bloodstream. Maybe you're a person who's body/brain adjusts slowly. Also could depend on previous or concurrent meds you've been on/are on.
I was prescribed it for severe depression and anxiety and it took a while for me too. its working great, just to encourage you. My doc and I played around with doses (oh joy lol) and too much made me more depressed. So the perfect balance for me so far is 150mg twice a day. It's very clean as in zero side effects as long as it's taken regimentally on time every single day. I set alarms on my phone. Don't give up.
I too started on a low dose of 25. I started to feel better about 2 weeks after starting it. I eventually got bumped up to 100mg. I felt absolutely great! I ran out of my prescription for about 5 days and once I got back on it I started to feel depressed again. Also at this time, my doctor increased my Effexor. I don't know if the stopping the lamictal for a week caused it or the increase in the Effexor but I feel like crap. It's been about a month and I still am feeling down, sad, and unmotivated. I know this is a really old post (2012) but was wondering if it ever helped or if you tried something else. Thanks!
Hi , I would like to share my recent experience with Lamictal.
I am 27 and diagnosed with BP2 about 6 weeks ago. My moods rapidly change since teenage years, from extreme confidence to extreme anxiety, depressive states where I wouldn't leave the house to being the biggest party animal. Also get extremely agitated and aggressive quickly (regardless what mood I'm in).
Started lamictal 4 weeks ago, 50mg taken once a day before bed. Like what some others said, one day I woke up and it was like a giant (good) slap in the face, suddenly felt light and like life was great. This was only 2 weeks in but was extremely obvious to me. Haven't felt this great since I can remember. My anxiety has reduced massively, don't feel down in the dumps/low self esteem etc. Also concentrate way better at work, more talkative (the list goes on!)
One thing I have noticed is that I feel like a semi hypomanic mood the last 2 weeks. I have read other blogs where people experienced this too and said it evens out eventually. Although my hypo moods don't upset me they were a welcome change from bad depressive states.
I am going to continue increase slowly to 200mg a day.
Also important, I exercise daily and also do yoga. Feel this is extremely important. If I didn't do this I doubt it would be so effective. I also have quite a fast metabolism and quite small so maybe that's why it has started to work so fast?
Re side affects - have definitely noticed hand tremors, forgetfulness (stopping mid sentence no idea what I was talking about ) and tummy upsets. Hope this goes away in time but the good definitely offsets the bad.
One more point- I also see doc for alcohol counselling. One day I took Lamictal after getting home from a big binge drink. Had the worlds worst hangover, threw up for 12 hours straight. I usually do not get bad hangovers. So think lamictal some how changes when mixed with alcohol. This was actually kind of good because I was so sick I do not want to drink. Im hoping Lamictal in conjunction with exercise and counselling will help in reducing impulsive drinking.
Hey! So I was diagnosed with bipolar II in August and currently at 100mg. I do a lot of exercise because I am training for a triathlon, and wondering if that is contributing to the lack of effects of the medicine or maybe I'm just impatient lol. When I first bumped up to 100mg, I had a minor case of hypo mania that lasted for about one week! I was so happy because I was talking a lot, I didn't feel anxious or self conscious at all, and in the back of my mind I was thinking this is too good to be true. I was right. I dropped from my mini hypo mania right back to depression. When I get depressed, I start feeling a weight on my chest that is always there, every time I talk to people my brain freezes and I can't have normal conversations! I also feel like everything I'm doing is so much effort and am super exhausted in the morning. Anyways enough about that.
I keep reading post about people feeling absolutely great after a while, but I am worried that I won't feel as great as everyone is saying. I can't live a normal life feeling cognitively lethargic and unable to properly socialize. That's literally all I want! I don't care about any other symptoms of depression, I can keep them all except for the fact that I feel like I can't think and talk to people. I'm so sick and tired of it. I want to be able to have a boyfriend, be a fun person and not be a stick in the mud. I'm not asking for hypo mania. I'm asking for a bridge in between the two.
I do hope you are feeling better by now. I'm in my 5th week of Lamictal (generic). I was on 25 for two weeks, then 50 for the other. I believe to warm me up without the rash. My normal psych wasn't in that day, which in a way I'm glad. The other psych put my 200mg right a way. My normal psych is very slow when it comes to increasing medications and to get to that does if at all would have taken months. The other psych that is the normal does. I didn't start 200 right way as I thought that was a huge leap from 50mg. So I've been on 100mg for the last five days. I'm not sure if I'm bipolar and well haven't been labeled too much, but I have a lot of tendencies of a lot of illnesses. But my moods were so out of control. I had highs and lows but mostly lows. I was very suicidal. Although I didn't try anything, I couldn't stop thinking about it. The psych also increased my Lexapro to 20mg instead of 10mg.
Which I'm glad he did. I even asked my other psych if he would increase it but didn't. I actually stopped taking it three days before I got the increase. THinking maybe I didn't need it. I was reading with those with bipolar should not take antidepressants alone. I started noticing right away. My moods had been completely calmed down. At 100mg I'm feeling more "myself" which I'm not sure who that is anymore, but more I am calmer, more relaxed and more present. I do take 10 other vitamins which I'm not sure are helping, but I'd like to think so. I'm definitely going to increase to 200mg. 100mg in the am and 100mg in the pm. The only side effects I've had is tiredness, but it should dissipate. And actually, some insomnia when the sleepiness wheres off. Hope all is well.
I have been on it for about a month and am about to go up to 4 25mg pills a day. I have noticed that every time I up my dose, I get really sad for a few days. I have a hard time staying focused and have no motivation to do anything. However, for me, it doesn't last long. I would imagine that if it lasts for a while with you, maybe it would be a good idea to talk to your doctor. There are other anti-epilepsy medications out there that you may respond better to. Just a thought.
- Lamictal Information for Consumers
- Lamictal Information for Healthcare Professionals (includes dosage details)
- Side Effects of Lamictal (detailed)
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