I was taking Seroquel last year for about 6 weeks for sleep. It worked really well for me, but I ended up gaining weight so I discontinued it. I am still having problems with sleep, so my dr prescribed Saphris, which I don't really like so far. I was thinking of going back to Seroquel. Do most people that are taking Seroquel gain weight? I was eating very healthy at the time and still gained about 10-15 pounds. My dr told me that it changes your metabolism, which leads to the weight gain. Is there any way to combat this?