... loss forgetfulness or other cognitive changes?
Do many people experience Lyrica side effects such as lack of concentration, short-term memory...
Question posted by GingerM on 10 April 2019
Last updated on 9 November 2022 by Gingermarie2008
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10 Answers
I have been taking Cymbalta for 20 years and Lyrica for 16 and am so hooked on them. I have Fibromyalgia and severe depression but would love to get off these. If I go longer than 24 hours without Lyrica I get deathly ill and Cymbalta after 36 hours gives me terrible brain zaps. My memory sucks and my train of thought left the station without me. I take the Lyrica when I go to bed because it knocks me out cold even after all these years. I wish there was something safer that would help with the pain. The memory issue is a real problem as I work in a call center and am required to remember tons of stuff and half the time I look at my screen and ask myself What am I supposed to be doing. I really want to feel like a normal person again. This stuff scares me.
I have been taking it for about 7 years and yes, I experience those side affects and uncontrollable limb movements plus blurred vision and more. It's addictive and it's hard to get off of it as well. Also some who try to call it "Lyrica hell" to me the pros out weigh the cons though. Hope that helps
Thank you all for sharing your experiences. It is hard to explain to people why am not able to converse like I used to or remember names, dates etc.
For now the pros outweigh the cons but I am looking forward to the day someone finds a fix so I can stop taking this medication.
Hang on, I forgot what the question was… no, seriously. I have had some real short term memory issues as well. Which can be convenient at times :) The biggest issue, (besides the price), is the weight gain ! I've put on probably 30 lbs from it, so I'm going to get more serious with the diet and exercise because the pain relief it provides can be priceless. **ByTheWay, it's supposed to come out in generic in June of 2019 making it Much cheaper. Which within itself will provide pain relief
I took pregabalin for 6 months. Was the best of all the meds I have tried and anxiety and reactive anger as good as disappeared. I started 3 X 50 and eventually was on 3 X 100. My wife noticed more forgetfulness. I found I was using inappropriate language - Happy New Year met my mum on Mother's Day. I could not find things in plain sight - literally. So I took myself off over 2 weeks. Felt better quickly but some withdrawal symptoms appeared and I'm working through these. I can say that being off the drug completely for 10 days I have more energy, memory challenges but I'm being more mindful of all I do that could have risk. Sleep in good if I hit 6 hours but it isn't continuous.
Weight - I'm a careful low fat sugar free, junk free, sad character but still gained 5 kilos but at least half fell off within days of my tapering down. Was urinating a lot so much must have been fluid. The fat gained is moving off too.
I tried Lyrica years ago for a very short time, could not tolerate the side effects. I opted for gabapentin instead which is helpful. But the drug cocktails that I have tried over the years have caused a plethora of side effects but I cannot live without help from drugs. Loss of memory, delayed reflexes , insomnia, dry mouth, hair loss, dizziness. It is very difficult for me to focus on any one thing very long and it takes me hours just to accomplish one small project. I tire easily and require rest periodically throughout the day. There is no one answer, just have to experiment to find the combination that helps so you can still enjoy a bit of your life. Chronic pain is a terrible condition and our only alternative to find ways minimize it.
Hi GingerM. I was prescribed Lyrica for chronic nerve pain but ended up with so many horrible side effects and it didn’t even help with the pain. I had anxiety, depression and suicidal thoughts. Along with dizziness and confusion. I forgot words and how to spell them. I had a hard time finishing my sentences. I gained a lot of weight too like others here have mentioned. I looked and felt like I was pregnant. I even talked to a trainer who said that she was gaining weight no matter how much exercise she got or how healthy she ate. I believe Lyrica screws up our metabolism and messes with our brain. I had many more side effects but I think you get the idea of what I think about Lyrica. I do believe however that once tapered very slowly off this medication and others like it we will most likely be back to normal. That’s what I’m hoping and praying for. I wish you the best with your health. Cindy59
Hi Cindy, thanks for your response.
I experience the above side effects you have mentioned, and they have become genuinely horrible. Many like the dry mouth, dizziness, confusions and weight gain I have just accepted as part of life. However, my cognitive abilities keep deteriorating the longer I take it, making it extremely hard to study.
I take Lyrica for nerve pain associated with neuromas and CRPS in my stump after I had an amputation. I desperately need to finish my degree, but the longer I am on Lyrica, the worse my grades and completion rates are getting. Unfortunately, I have not been able to find an alternative and am trying to get other peoples take on Lyrica so I don't feel like I am crazy for thinking it may be the cause.
Hi GingerM. I’m so sorry you’re going through this. I can’t believe Lyrica is still being prescribed after years of people complaining about the side effects. There’s no way the FDA or many of the doctors don’t know the problems people are experiencing from this drug. After I finally tapered very slowly off Lyrica (because of all the side effects) I made a bad decision to listen to my doctor to try another medication. It’s Cymbalta and a lot like Lyrica; but in my experience it’s even worse. Thankfully I’m almost tapered off that now too and I’m starting to feel ‘normal’ again. I am able to read again and remember what I read. I’m losing weight and the swelling throughout my body has gone down a lot. I’m running at a normal temperature most of the time so no problem with excessive sweating. My hair has stopped falling out which is great. My eyesight and hearing is good again.
The worst thing for me now is that the dry mouth side effect has left me with losing teeth and many cavities. I’m not sure if I’m going to be able to keep my teeth or if I will end up having them all pulled. I live alone and I can’t work so money is tight so I’m not sure if I will be able to afford dentures if that happens. I have no idea how you are managing studying being on Lyrica! I have a hard time to just get through the day. I hope and pray that you get through it and maybe you will think about tapering off very slowly. Doctors usually taper us off way too fast and we end up going back on the medication again because we think we need it. But it’s from the withdrawals from tapering off too fast. I am really so sorry for what you’re going through. Have you researched natural remedies that might help you. These types of medications deplete our bodies of so much also. Especially Vitamin B12. I take Complex B100 and I found it’s made a huge difference for me. Sorry for the long comment but I get angry when I hear that one more persons life is being harmed by Lyrica and/or medications like it. Best wishes to you. x Cindy
You said something that interested me and that was hair loss. I have went to doctor complaining about that. Thank You for mentioning that. I also have been confused on different thing and definitely memory lost like really really bad in the last 3 months. I need to get off this medication before I end up losing all my memory.
Hi msdeborah6963. I’m sorry you’re going through this too. The confusion and memory loss is very hard to deal with. Most people don’t understand. And the hair loss; wow! I didn’t know if I was going to have any hair left. It’s a good thing I had lots of it or people would have probably noticed. Now that I’m tapered off Lyrica and close to being off Cymbalta I have my full head of healthy hair back. The confusion is gone and I no longer have to deal with memory loss. The only thing I have left to recover from is lack of energy. It is getting much better though so I’m thankful for that. Have you seen the posts on Facebook about antidepressants, all the side effects and how hard it is to get off them? The truth is finally coming out. One of them talks about how doctors need to warn their patients about the many side effects of these medications and the dangers of coming off them too fast.
Well; I wish you the best and if you decide you want to get off Lyrica there is an amazing group on Facebook called ‘Lyrica Survivors’ where they are all tapering off this medication. There is a lot of good information in the files such as how to taper off properly; natural remedies that can help you and much more.
Take care x
I cannot take Lyrica. After taking for 4 mos., I became extremely suicidal. All my conscious thoughts were about how to end my life. I immediately stopped the meds and reported them to dr. Definetly. For me.
Hi! Ive beem taking Lyrica for about a year, I think. My memory is extremely bad!!! But I also have epilepsy, not controlled, but yes I totally agree with you about things moving slowly and slowly with anything Im trying to do. Its like im in slow motion. My reaction time is very delayed!! Even my husband has mentioned something about it before. Yesterday I couldnt remember what city I was born in and my current zip code!! And ive been living here for 39 yrs!! It was weird and made me worry about my memory getting worse! Also when I saw that Lyrica causes weight gain, I was determined not to let that happen. But, even though im watching what Im eating and how much and only drinking water..Im having a hard time losing weight! Which is frustrating!! I can eat a meal and then 10 min. later I feel like I havent ate anything and im starving. Its hard! I will lose a pound or two and then the next day I will have gained 2 or 3 lbs back.
Its very frustrating!! Im taking this drug for trigeminal neuralgia and for my epilepsy. Im 40 yrs old but definitely dont feel it, feel much older!! I would just try and watch what you eat and portion size and atleast walk or try and do some kind of exercise. But, good luck to you!!
Yes from time to time and if you are taking other medication mixture could be causing this as well It can make you overtired or seem like you're overtired it can give you an attitude. most of the time now I take four different medication and I have side effects such as sleepiness getting too hot I can get too hot in the winter time outside and I do sweat keep in mind this would be a mixture not just from one pill but when you get this pill you usually get a piece paper stating side effects and what it may do to you and may not gaining weight is not one that I recognize but I can find out keep in mind this can be because of more than one medication I take four different medications and it can give me the side effects of overtired attitude and sweat as well check and see if you may have an anxiety problem this can be a big cause in it as well if you are gaining weight I would suggest slacking off some fattening foods but I can't say this may be part of it if you would like to get back to me about this I'll be happy to try and help you
The biggest change is not that I LOSE the above, but that my brain and body operate much more SLOWLY. It takes me three or four times as long as it used to just to read the daily newspaper..or a book. Concentration very slow and information difficult to retain. I am also gaining weight which I think affects cognitive ability as well as physical.
Thanks for replying Nina, are you still on Lyrica? Do you mind me asking what dosage you were or are on?
I am experienceing pretty bad cognitive side effects like the above, including the weight gain. I have been on it since 2015 and can not seem to find an alternative that works.
I take 82.5 mg time release, but supplement with medical marijuana. I am planning to go for intercostal nerve block soon. My shingles damage was in right upper quadrant of my body, so I am good
candidate for it.
I’m noticing memory loss, hair loss, not always understanding and confusion... Some things I’m forgetting then some I remember. I’m going to slowly get off this medication.
I have been on lyrica for the treatment of benzodiazepines withdrawals. It's helpful for panic attacks or anxiety but only in high dosages.But it is very depressing and causes more problems then it's worth. So l have quit several times due to the confusion and Depression brain fog. Withdrawals last ages in my opinion and Drs now seem to have most patients stopping and starting and unless you keep going up the effect of lyrica seems to vary daily. One day it works the next day you feel strange or something isn't right. The withdrawal is very intense and l believe that tapering is a long as process. I was reducing at twenty-five mills a week the first time around and l felt so very I'll mostly a Depression that is so bad it's why it's life threatening to stop abruptly. But my last time l cold turkeid and l am still feeling crap. I n my opinion stay away from lyrica and benzodiazepines.
Related topics
lyrica, diabetic nerve damage, epilepsy, persisting pain, shingles, fibromyalgia, neuralgia, diabetic neuropathy, postherpetic neuralgia, side effect, neuropathic pain, memory, concentration, short-term memory
Further information
- Lyrica uses and safety info
- Lyrica prescribing info & package insert (for Health Professionals)
- Side effects of Lyrica (detailed)
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