Has anyone switched from generic Lexapro (escitalopram) to generic Pristiq (desvenlafaxine) with success? Was on Lexapro 20mg for about 5 years and then it stopped working for my anxiety and panic disorder. Was having bad panic attacks. Doctor put me on generic Pristiq. Started with 25 mg for 2 weeks and then increased to 50 mg while slowly tapering off the Lexapro. I am having horrible headaches and feel agitated. I have been on the Pristiq for 5 weeks now and am wondering if the headaches are from the Pristiq or the Lexapro withdrawal. I am also having regular panic attacks but they don't seem to be as powerful but that may be because he gave me 0.5 mg of Klonopin to use as needed. Doctor says Pristiq is a better drug for panic but I am wondering if anybody has had success with Pristiq for anxiety & panic attacks? Thank you