My doc recently raised my dosage of Wellbutrin XL from 300mg to 450mg daily. I haven't felt right since the increase 18 days ago, slight headache daily, sticky stomach sometimes, anxiety, depression. Has anyone else experienced this upon a dosage increase? If so, how long did it take you to adjust? How long did it take for you to start to feel better after starting Wellbutrin XL? Would coffee exacerbate the side effects of this med? Also does anybody notice a difference between different brands of this drug? I also take paroxitine 60mg daily for 20 years (that really sucks I know), and clonazepam 1mg 3 times daily, as needed, for 20 years, used to be 4 a day, but I went to 3 several years ago. Was on doxepin, weaned off that 2 months ago. Any input would be appreciated