The plasma half-life of levodopa is about 50 minutes, without carbidopa. When carbidopa and levodopa are administered together, the half-life of levodopa is increased to about 1.5 hours. At steady state, the bioavailability of carbidopa from SINEMET (carbidopa-levodopa) tablets is approximately 99% relative to the concomitant administration of carbidopa and levodopa.
With regars to the side effects, can you let us know which ones you are experiencing in order to give you the right answer?
- Sinemet Information for Consumers
- Sinemet Information for Healthcare Professionals (includes dosage details)
- Side Effects of Sinemet (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Posted 30 Apr 2010 • 1 answer
Is it safe to take Kalms Night tablets (1 each night) to help sleep problems while taking sinemet CR
Posted 15 Nov 2011 • 1 answer
Posted 19 Apr 2012 • 1 answer
Posted 18 Oct 2014 • 4 answers
Posted 8 Feb 2016 • 4 answers