I've been on Cymbalta for close to 2 years for musculoskeletal pain from RA and SLE. I have extreme bouts of uncontrollable sweating even after all this time. I thought it was going to be a temporary side effect that I would eventually get over. Now, here I am... 23 months later and still miserable. I imagine it is what menopause would be like. I am 37 and not near menopause according to my labs. The actual temperature has little to do with my symptoms. I would hate to have to come off of this but I can't imagine another Georgia summer this way. These episodes just come on with little to no exertion. No new meds since beginning this and jaw-clenching and sweating have been apparent since. Any suggestions?