I've been on Cymbalta for close to 2 years for musculoskeletal pain from RA and SLE. I have extreme bouts of uncontrollable sweating even after all this time. I thought it was going to be a temporary side effect that I would eventually get over. Now, here I am... 23 months later and still miserable. I imagine it is what menopause would be like. I am 37 and not near menopause according to my labs. The actual temperature has little to do with my symptoms. I would hate to have to come off of this but I can't imagine another Georgia summer this way. These episodes just come on with little to no exertion. No new meds since beginning this and jaw-clenching and sweating have been apparent since. Any suggestions?
Does anyone have sweating with Cymbalta (duloxetine)?
Question posted by erika8579 on 23 March 2017
Last updated on 18 October 2023
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
18 Answers Page 2
SweetLuck
24 March 2017
Yes! I dislike the sweating it causes so much. My clothes will get wet and stick to me even in winter. It's uncomfortable. I don't want to go off it either as withdrawal from it is a nightmare (at least it was for me the one time I did stop) but you could consider switching antidepressants after researching others. Also, Gabapentin is used for hot flashes (I know they're not hot flashes but excessive sweating) off label if you might want to consider that. Good luck.
chuck1957
23 March 2017
Ericka; depending on how this medication is working for you talk to the doctor about the sweating problem, Sometimes they can give you something to counteract that prior to changing the medication if it is working well for you. But this is a common side effect. Some it does go away and others it keeps up. Don't worry check with your doctor and let her or him know what is going on and see what their answer is. There are others very similar to Cymbalta that may not cause the sweats. Best of luck
srandjlsims
23 March 2017
I have menopausal and Cymbalta sweating, its truly miserable, however, I got put on Buspar/Busparin. I know it will seem like just one more pill, but I can't live without Cymbalta, literally, so the Buspar is a miracle worker. Last summer was NORMAL! LOL!
khester1030
15 March 2018
I'm on Cymbalta 60 mg & have been for about 5 years now for anxiety. It does the job but my night sweats are something else. I wake up covered from head to toe in sweat (even in the winter with 2 fans going). Were you put on the Buspar/Busparin while taking Cymbalta & the sweats stopped?
Hernandez17
28 April 2021
I’ve been on cymbalta for 6-7 years. I sweat every day even in winter. I can’t be without cymbalta either. I’m going to check with my doctor about buspar. Thank you.
Related topics
cymbalta, depression, rheumatoid arthritis, hyperhidrosis, anxiety, pain, hot flashes, duloxetine, chronic pain, systemic lupus erythematosus, musculoskeletal
Further information
Similar questions
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.