I am currently on 150mg of Effexor. Overall I am very happy with my progress but the only problem I have is that I have terrible nightsweats. The sweats are so bad that I have to change my pj's twice a night and put a towel down on my soaking bed. My whole body from my head to my toes sweats, I am literally dripping with sweat! My consultant says he has never heard of anyone else having such severe sweats. I would really like to know if anyone else has such bad night sweats?
Does anyone else suffer from extreme nightsweats while taking Effexor?
Question posted by sweatybetty on 26 June 2014
Last updated on 21 October 2024 by Jojoprit82
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53 Answers
I have been taking Effexor 225mg for approximately 4 years and have extreme night sweats, I am completely drenched and freezing all night. If I miss a dose I also experience awful nightmares and awake numerous times a night and then in the morning my body feels shaken and i feel confused. I am all taking Amitriptyline 75mg, Promazine 50mg and Mirtazapine 45mg.
Does anyone else take this amount of antidepressants? Thanks
Yes, almost every night. It is one of the damn side effects!! been taking Effexor XR for over 20 years. It goes on and on and on!
"Dermatologic
Very common (10% or more of users): Sweating (up to 19.3%), night sweats (up to 11.4%)"
Talk to your doctor!!! There are medications, even some OTC's, that can help minimize or eliminate these symptoms.
oh yes, I am getting them real bad too! It is awful.
I’ve taken Effexor 150 XR for 3 plus years and it has caused extreme night sweats. I can feel the sweat dripping off me. I accidentally got another medication confused with my generic brand. With in days the sweats completely stopped and I weirdly felt CALM and emotionally happier.
Night sweats is probably my number one side affect when taking Effexor...
It's not only inconvenient, it's kinda embarrassing. I drench the sheets most nights so snuggling up to your bed partner gets a little sticky... I usually go to bed with an ice pack on my neck to help cool things down... I usually wake up pretty cold due to my skin being moist from the excessive sweating throughout the night... I wonder if I should try Pristiq(sp?)... it's supposed to be the "cleaner" and "newer" version of Effexor... Any thoughts?
Until I read forums like these I assumed that the night sweats were menopause related. However, it got way worse when I went from 75mg - 150mg. My doctor suggested the increase in dose to reduce night sweats, but it made it worse. It went from being occasional to every night drenched! Thank you all for your comments. It is very helpful to hear.
You might want to consider taking your Effexor in the morning instead of in the evening and it will stop the night sweat but you will still get the sweats about 20 min before your does. As Effexor raises your body temp as the medication leaves your body. There are also medications you can take with your Effexor if you still want to take it in the evening to eliminate the problem
Yes me too. Did you ever find a cure
Yes i do . Very frequently. I have been on various anti depressants since my diagnosis of P.T.S.D.back in 2003, i also suffered with irregular sleep patterns and sweating on sertraline. I am also having more frequent nightmares the date today is . 14th of April 04.59
I'm a 33 year old male, I've been taking effexor 37.5 once daily for about four months. This drug has changed my outlook on life for the better. But I wake up every night completely drenched. I didn't now that much liquid could come out of the body. Tried switching meds but they haven't worked as well. Is there away around this very wet side effect ?
Please talk to your doctors... especially if you don't want to stop your Effexor. There are multiple medication options that can minimize or completely eliminate antidepressant induced diaphoresis (excessive sweating) without having to switch to another antidepressant.
Wildcat, ive been to my doctor numerous times and referred to consultants but none have offered medication options to reduce the sweating whilst still on Effexor. Can you tell me what options there are so that I can pass them on?
Many thanks
You could try asking about the anticholinergic medications such as benztropine, propantheline, oxybutynin, etc.
Also cyproheptadine which is an antihistamine.
The antidepressant mirtazapine has also been successful in some people.
These won't work for everyone, but they might at least be discussing with your health care provider.
From Clinical Psychiatry News MDedge/Psychiatry:
"the anticholinergic agent benztropine reduced or eliminated diaphoresis at doses ranging from 0.5 mg every other day to 1 mg/d.2,3 Dry mouth was the only reported side effect.
Centrally acting serotonin antagonists may decrease diaphoresis through the 5-HT2A receptor, which signals the hypothalamus to raise body temperature. Cyproheptadine is an antihistamine with serotonin receptor antagonism. In case reports, it reduced or eliminated sweating in doses of 4 mg once or twice daily.4 Mild sedation was the only noted adverse effect. The norepinephrine and serotonin antagonist mirtazapine reduced diaphoresis within 2 weeks of initiation at 15 mg/d with no adverse effects.5 Sweating resolved after mirtazapine was titrated to 60 mg/d."
Best regards and good luck. WC
oxybutinyn
cyproheptadine - antihistamine
mirtazapine -antidepre
Yes. I wake up completely drenched and freezing. I've been on Effexor for 7 months now with a dosage increase and my night sweats haven't decreased.
Hello all, I have been on venlafaxine for about a year, I increased my dose about half a year ago from 75 up to 150 and had the same symptoms as most of you describe. Waking up multiple times a night drenched, etc..I have been paying close attention to my eating habits and found a close correlation between my night time snacks and my sweats. I found that if I ate carbs before bed(within an hour) I would wake up sweating. While if I had a high protien or fat snack, I didnt wake up. I dont know if this based on anything sound, just my own experiences.
Also, my mother also takes it and she takes it at night and gets her sweats during the day. But she has poor earing habits all together.
I'm getting up 3-4 times a night changing PJ's and I'm only on 75mg per day. Love the medicine itself. Was on it 15 years prior to coming back to it a couple months ago. Thing is I never had this problem taking it before. So it's too feel great and sweat like crazy or deal with PTSD and no sweats. I think I'll ride out the sweating unfortunately.
Related topics
effexor, depression, hyperhidrosis
Further information
- Effexor prescribing info & package insert (for Health Professionals)
- Side effects of Effexor (detailed)
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