I was on Serzone for years until they quit making it. My doctor put me on Cymbalta and I absolutely love how it made me feel. I started noticing that I was having muscle cramps a lot. Finally the cramps got to be so bad that I talked to my doctor about it. He changed my medication to Pristiq and I have been on it for 6 days now. I noticed a decrease in the muscle cramps for a few days, but yesterday and last night were one of the worse days ever. Does anyone else suffer muscle cramps from either of these medications? I am at wits end. I have cramps in places I didn't even know I had muscles. So so painful.
Cymbalta can cause muscle spasms, and pristiq is related to cymbalta.
Hello kytracer. I did some researching on your question. Both come from the same family of drugs (SNRI) But I found nothing in regards to leg cramps on either drug. I was on Cymbalta for several years and in my case it wasn't an issue. Now in regards to Pristiq, muscle pain is reported in between 2to 5% of people taking the drug. If it persists, I'd speak to your doctor for theres no guarantee that the cramps/aches are going to lessen or diminish. Regards pledge
Increasing your intake of magnesium and/or potassium will probably correct the problem.
I just started on Pristiq and am having massive leg cramps. I take prescription potassium so that is not helping. I am going to call my dr tomorrow. To much pain. So your not alone.
I've been on Pristiq for a couple of years and have noticed that in the last year, I've had increasingly more and more severe leg cramps. Sometimes I have much pain with standing, sitting and walking. When going from standing to squatting and standing up from squat position my legs almost give out. I just Googled Pristiq and leg cramps and am relieved to see other people are experiencing the same symptoms so this may explain mine.
I've had such severe muscle cramps that is actually dropped me to the ground and I was immobilized for several minutes and it made walking nearly impossible. I don't know what's up.
It's listed as a serious side effect of Cymbalta. I'm going to see the Dr. As I was using it for chronic pain. Good results for reducing flu symptoms of fibromyalgia. Obviously sucks for muscle pain.
I've used Pristiq for over two years and developed severe muscle cramps in lower legs that woke me from sleep and couldn't walk. I discussed this with my physician and pharmacist and registered massage therapist. I increased water consumption, started talking magnesium supplement in the evening and have regular massage treatments. Done! No more muscle cramps.
When I was a few days into the medication I had fairly extreme leg cramps that kept me awake at night. The cramps seemed to have gone away already. I do have intermittent pain in certain bones. My knees have had severe pain where there has never been pain before. I mention this because I am a contractor and have been banged up and over-used over the years. The medication has already helped with arthritis, GAD and depression which are all related to PTSD. I am on boatloads of other medication as well. I am still on a baby dose of 20 mg. Cannot imagine being able to work up to 60 or even 40. Thanks for reading and would love some responses.
This is concerning news for me. I have taken 30mg for a week and today, my second day taking 60mg, my legs started to hurt badly. Most of the pain is in my legs but there is aching in my back, my shoulders, my hands and my forearms. They are sore to the touch like they are bruised.
I just switched from escitalopram to treat my anxiety and depression, and I’m getting a bunch of other side effects too.
I have had severe nocturnal leg cramps for 3-4 years. At first I thought is was steroids from treatment for eosinophilia. The pain was so bad I had severe sleep deprivation. Then after I was no longer taking steroids the cramps got worse -of course no one would give me codeine for the pain. I was offered one muscle relaxer by a rheumatologist and another by a neurologist. They screwed me up so bad I was falling. Then I finally saw a neurologist in Houston who put me on dantrolene, a powerful older generation muscle relaxer that works at the muscle and not through the brain. Makes you feel like a zombie but cramps stopped. I took it for 6 weeks until my old rheumatologist who had quit practicing called and said it was Enbrel I was taking for other autoimmune disorders.- he knew immediately because he had seen it in other patients after 30+ years of practice I stopped Enbrel and 95% of the cramps stopped in six weeks without dantrolene.
In the meantime my psychiatrist added Wellbutrin to my Cymbalta asI was so depressed. Wellbutrin has a side effect (rare) and last night I started cramps again and had to take adantrolene. It was really bad. So, I cold-turkeyed the Wellbutrin thinking another drug reaction. My sister just sent me this and now I guess it could be Cymbalta too which I’ve been on for years. I’ve done pain management and spent a week at Mayo. Cramps mainly in legs but also hands and arms. I’m so sore I can’t go up 3 stair without a railing and I’m only 62. But I’d rather be depressed than have cramps with no pain relief and sleep deprivation.
I've been on Cymbalta (generic) for 6 days, I have had 2 Charlie horse on the 4th day on one calf and 1 on the 5th day on the other. Drinking water and rolling out calf muscles as much as I can... hopefully no more...
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