I was on Serzone for years until they quit making it. My doctor put me on cymbalta and I absolutely love how it made me feel. I started noticing that I was having muscle cramps a lot. Finally the cramps got to be so bad that I talked to my doctor about it. He changed my medication to Pristiq and I have been on it for 6 days now. I noticed a decrease in the muscle cramps for a few days, but yesterday and last night were one of the worse days ever. Does anyone else suffer muscle cramps from either of these medications? I am at wits end. I have cramps in places I didn't even know I had muscles. So so painful.
Hello kytracer. I did some researching on your question. Both come from the same family of drugs (SNRI) But I found nothing in regards to leg cramps on either drug. I was on Cymbalta for several years and in my case it wasn't an issue. Now in regards to Pristiq, muscle pain is reported in between 2to 5% of people taking the drug. If it persists, I'd speak to your doctor for theres no guarantee that the cramps/aches are going to lessen or diminish. Regards pledge
I've been on Pristiq for a couple of years and have noticed that in the last year, I've had increasingly more and more severe leg cramps. Sometimes I have much pain with standing, sitting and walking. When going from standing to squatting and standing up from squat position my legs almost give out. I just Googled Pristiq and leg cramps and am relieved to see other people are experiencing the same symptoms so this may explain mine.
I've used Pristiq for over two years and developed severe muscle cramps in lower legs that woke me from sleep and couldn't walk. I discussed this with my physician and pharmacist and registered massage therapist. I increased water consumption, started talking magnesium supplement in the evening and have regular massage treatments. Done! No more muscle cramps.
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