strange effects
Acetaminophen/Oxycodone - problems with Rhodes manufqcturing rp 10/325?
Question posted by steele_dollahite on 17 Feb 2016
Last updated on 8 June 2024 by wjm0720
15 Answers
Changing to Rhodes brand caused my mother, who is 81yo to be so dizzy she couldn't stand up! Went on here to see if anything was documented and see it is not uncommon!
I am so glad to see I am NOT the only one with this problem. These Rhodes pills are NOT effective. There is definitely something wrong with them. CVS is constantly trying to push them on me and I always have my doctor write in the prescription that the pills must be from Mallinkrt Pharm. But CVS always tells me that the Rhodes product is the only one they can secure. I suffer because they can't get it right.
I get 10/325 every once in a while to get through really bad pain times as my whole spine seems to just be falling apart. I always felt some kind of relief from previous 10 325 prescriptions until today, when CVS gave me Rhodes RP 10 325's. I immediately noticed they're small round tablets and not the oblong big ones I've always received but thought "who cares" what they look like as they should be the same since I got them from CVS. So far, after taking these tablets, as prescribed, one at a time every 6 hours for a day, and... Nothing. They aren't doing anything.
Rhodes Morphine and Percocet are junk and provide no pain relief. PA, w/o notice, suddenly lowered dose my MD just increased, when I stated Rhodes is useless with numerous complaints. I can't function and asking my original dose reinstated. No pharmacies stocks the best med, Malinckrodt, as inferior Rhodes is cheaper. FDA must inspect this lab, as we chronic pain patients are severely suffering!
Oh good. I'm not the only one. I recently picked up the Rhodes brand, a day ago and so far, nothing. No relief or anything compared to what I've always received from my CVS prescriptions with previous and obviously different brands. I've never even looked at the brands for Percocet's, I just took as prescribed until I got this Rhodes brand. These RP 10 325 's aren't relieving any pain at all.
Not only did they not help after 8 days I started to have withdrawal symptoms which was my final breaking point. I had to actually pay for the pharmacy to replace my medication. Fortunately I have wonderful children and they got the money together. I need a pharmacy I can trust. I am in Palm Coast Florida does anyone have any ideas where to go?
Please file a complaint. I even called Rhodes who did call me back and took a full complaint. I also called my insurance and of course the pharmacy and filled out and sent an online FDA complaint form.
I am a chronic pain sufferer who won't go into details But I have been on pain medication for 21 years.
always did well with Oxycodone 10/325. Just had my prescription refilled at Walmart. the pills looked different and smaller. There now using RP brand. I took 1 and started feeling very sick. went to bed trying not to throw up. I am shakey and dizzy and just feel awful and felt no pain relief.
this medication is not good. What I used to get. Don't know the manufacturer had no side effects whatsoever. I just feel sick from just 1 pill. Can't get anything done on this brand of Oxycodone
I suffer from chronic pain and have been on oxycodone for many yrs. without problems recently had filled a r/x for 10/325 at CVS have had nothing but problems headaches and 0 pain relief manufactured by RHODES
i also have experienced bad case of blurred vision i will not use.
Me too. For years I got occasional relief when my spine is acting up, and then occasionally prescribed Percocet. Picked up the Rhodes brand for the first time recently and they aren't relieving my pain, and it's as if I took nothing. Luckily I don't take Percocet every day so I can get through it, but I feel for a severe/chronic pain user who picks up the Rhodes brand.
I have major chronic pain after a C-spine injury. I have noticed as well issues with the Rhodes manufacture. However I have also noticed that pharmacy are only carrying this manufacture. I had to file a complaint with the FDA, in hopes to get to the bottom of the problem with their medications. I get no pain relief either as well as instant migraine and nausea. If you expenrience issues there is a website you can go onto and file a report. the more of us that file reports the sooner they will investigate them. https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program This should help you get to the site.
Thank you for posting the website to lodge a complaint. I hope others will followup. Rhodes is the only brand stocked, period. Special orders for different generics are no longer permitted.
This medication does absolutely nothing. How can they get away with this? I took triple the dose and still nothing. Fortunately no stomach issue like others reported. Nothing at all. Like I didn't take anything at all.
Yes! I’ve been suffering from chronic pain and degenerative disc disease among other pain causing illnesses for more that 15 years. I have been prescribed Percocet 10/325 for many of those years, always received the generic version and didn’t experience any side effects. More recently, CVS has started to dispense Rhodes generic and that’s when I noticed a decrease in efficacy ( no pain relief!) and some unwanted side effects. Some are associated with GI issues ( stomach pain, diarrhea etc.) and I see from previous comments, where these could be caused by lactose in the list of excipients in the Rhodes generic and related intolerance. However, I also started sweating profusely after taking each pill and noticed accelerated heart beat.
I have lowered my dose since to 5/325 but the sweating and palpitations didn’t decrease. I can only deduct that these side effects are caused by Rhodes generic Percocet. The generic equivalent I have received at the hospital and /or ER doesn’t affect me and yet relieves the pain.
I find it worrisome that many patients( me included) have “unusual “ side effects while on Rhodes Percocet; if it is indeed a cheaper generic and used by one of the largest retail pharmacies for financial reasons, then this might be a larger issue to be looked into. Chronic pain patients are owed some answers. Life with pain can be complicated enough without having to worry about the efficacy and (safety??? ) of a generic drug like Rhodes Percocet!!!
I have had 4 operations for chronic back pain and have been using various manufactures of 10 mg Oxycodone for more than 15 years. My experience with Rhodes Pharmaceuticals Oxycodone 10-325 was as if I had taken a foul-tasting placebo. I received absolutely no pain relief and suffered opioid withdrawal symptoms after taking maximum dosage. I am now doomed to suffer withdrawal and remain in acute pain for a full month. There appears to be no solution for this dilemma and dozens of similar complaints about Rhodes-manufactured Oxycodone appear throughout the Internet. Would that I had done a google search before accepting this product from CVS. Someone should file a class action suit and FDA should pull Rhodes pills off the market. Rhodes and Pharmacies that sell this cheap, worthless, product should be ashamed and boycotted.
So I have to share my 2 cents about Rhodes. I’ve been using this generic for almost a decade. It works very well for me and has never made me sick. Even with the very first time I took it when switched. The other names listed (I can’t remember them, sorry), I have read so very many negative comments about them, and for the same things... making people sick and not having any pain relief. I think it depends on what you take first: what your body comes to expect from the oxycodone. It’s the fillers that are different. So if you’re started on Rhodes, you get used to it quickly and it works well for you. If your pharmacy changes generics and you’re given a new one, then I can totally understand getting sick from it. With the fillers being different, your body is now having to process it completely differently. So people react to it, and with continued use would get used to it and then it would work. I think this is why there is so much difference in people’s opinions of each brand.
I am a male in my 60s … have had to take generic versions of this drug for 2 decades off and on. Around Oct of last year (2018) I got a regular refill, when I got home I noticed it was not the usual brand … but I took it, it didn't seem to work, gave me an odd feeling and it gave me > well lets just say I had to live in the bathroom on the toilet. I stopped taking it … the problem went away. Started it up again … same problem. I threw it away. Next month same thing happen … if I took Rhodes I got almost uncontrollable trips to the toilet … stop the drug they went away …. had to inform my pharmacy that I could not take this version.
I found out many pharmacies started stocking this brand because of low price cost.
As I said, because of a injury and muscle condition I have take this off and on for 25 years > and never had this issue until I was given 10mg/325mg manufactured by Rhodes
Look up the ANDA #. That brand may have Lactose in it. KVK-Tek does that to many because of the Lactose.
KVK Tech and Mallinckrodt are great! I've never been sick on pain meds until RHODES! IT IS PURE GARBAGE and dozens agree. We all can't be wrong! You call and they say youre screwed, like the no compassion pharmacy. No refunds/returns, you must fight for another script, then get an insurance override to replace this life threatening poison, putting many in the ER. I literally feel like Im dying; first vomiting and migraines. Now severe abdominal, chest and kidney pain to where I can barely walk. Suffering 2 weeks now. I cant see my MD to replace this garbage; and worse it doesn't relieve any pain whatsoever, even in higher doses. Pharms: PLEASE, WE'RE SUFFERING, our insurance and we pay good $$$! Spend a little more for a quality brand! Our lives depend on it! REMOVE THIS POISON NOW! Im making a FDA complaint!
Your experience sounds almost identical to mine. I am so sorry. Please look at my post that has the link to the FDA to file a complaint.
When my pharmacy changed manufacturer to Rhodes last October 2018.
I went in to pick up my Percocet 10/325 mg tab rhod
I notice right away the taste then the feeling of getting sick from it.
I contacted my pharmacy with my concerns and that is when they told me they changed to a new manufacturer Rhodes. They proceeded to tell me drink milk or eat something before taking it.
I have been taking this medicine for over two year and have always eaten and drank milk before I take any medication, I just never got sick from this medicine until they changed manufacturers. Not only that it’s not taking the pain away like it did before the change. I don’t want to take more than what my doctor is prescribing, I am in so much pain asking my doctor if there was anything stronger to take the pain away.
Still to this day with the same manufacturer I get bad taste and get sick from time to time.
Unfortunately, in most cases, generic pain medication has some negative and unwanted side effects not experienced by brand name medication. In this day and age, most pharmacies have had to prescribe the cheapest generic available in order to increase their bottom line. The cheaper the generic, the more negative side effects. From what I have read, Rhodes manufactures inexpensive generic pain medication which makes it attractive to some pharmacies. I might suggest that you do a little pharmacy shopping until you find a generic equivalent that works for you. Don't believe anyone who tells you that all generics are the same, and work the same as the primary brand name drug. They are not. Best of luck to you.
It is now 2020, so you may not even see this answer but other people have complained about Rhodes as well over the last 4 years. It just seems that these new generics are much less effective and/or causing a lot of us stomach problems. Myself included. Check medicine reviews on this site. It helped me a bit.
Has anybody used Rhodes Pharmaceuticals Oxycodone?
I unfortunately broke my ankle last night walking my dog. The 5mg x 2 Oxycodones they gave me in the hospital ED worked fine last night. I picked up 15 generic 5mg Percocets made by Rhodes Pharmaceuticals at my local CVS today. They seem like garbage. Has anybody else tried these generics? I am having surgery next Wednesday. Is it worth requesting and paying for brand name Percocets? I appreciate any feedback
Hospitals don't use generics and for good reason.
Thank you everyone for the information. I thought there was something going on.
At least I know now I am not the only person out there that is having problems with this manufacturer. Rhodes
Steele; I have looked this up there should not be any problems, There really is no difference all this has is the 2 ingredients in it and this is an Sch II which has the tightest restrictions of any medication Check with your doctor if you're having problems with this you more than likely would with any brand. The Oxycodone comes from the same place and generic Tylenol is all the same.
You're a shill Rhodes rep. I FAINTED AND SPLIT MY HEAD OPEN! Ceased this poison, I threw up two weeks, my stomach boiling, kidney and chest pains. Couldn't get script replaced for 10 days! By then, override expired, paid $100 for partial fill of 80 would've been $3. Worse, pharm refused fill with Mallinckrodt after waiting 2 hours until next day where i sat crying in agony! I even rushed to ER that night; zero help, finally called medics, again 0 help. I went into a seizure, as your blood pressure drops in severe pain which causes fainting. I recall them saying "whoa", as I could barely walk, sat me in a chair then left! I came to with blood all over kitchen, counter floor and a gash in my head! I can't recall event sequence, trying to recreate is scary, as well. I obviously wasn't inured when they were here. Claim I refused transport, after calling in desperation. W/o big hassle, I cant get the report.
This is serious! I'm alone and could've bled to death, had my injury been more severe. I finally recovered to bandaid wound. I bought better sealed bandages with a med in it, praying for no serious scar. Still NO idea what I struck! Blood only on pillow and trail from kitchen to bed. Must've tried making tea, saw cup of water and honey. Finally semi functional, still weak have a bruised, CUT aching head, jaw and shoulder! NEVER, EVER has this occurred in my life! On same meds and doses 25 years. This is egregious! Rhodes should be forced to ban this poison NOW!
Related topics
pain, acetaminophen, acetaminophen/oxycodone, oxycodone, chronic pain
Further information
- Acetaminophen uses and warnings
- Acetaminophen / Oxycodone uses and warnings
- Oxycodone uses and warnings
Similar questions
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.