Zaleplon Side Effects
Some side effects of zaleplon may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to zaleplon: oral capsule
Zaleplon may cause a severe allergic reaction. Stop taking zaleplon and Get emergency medical help if you have any of these signs of an allergic reaction while taking zaleplon: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using zaleplon and call your doctor at once if you have any of these serious side effects:
aggression, agitation, changes in behavior;
thoughts of hurting yourself; or
hallucinations (hearing or seeing things).
Less serious side effects of zaleplon may include:
day-time drowsiness, dizziness, "hangover" feeling;
problems with memory or concentration;
numbness or tingling;
anxiety, depression, nervous feeling;
problems with vision;
nausea, stomach pain, loss of appetite, constipation;
increased menstrual pain (cramps);
back pain, joint or muscle pain; or
mild skin rash.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
For Healthcare Professionals
Applies to zaleplon: oral capsule
General side effects including headache (28% to 38%), asthenia (5% to 8%), fever (2%), malaise (<1% to 2 %), and photosensitivity (<1% to 1%) have been reported.
Nervous system side effects including dizziness (7% to 8%), somnolence (5%), amnesia (2% to 4%), anxiety (less than 1% to 3%), paresthesia (3%), depersonalization (less than 1% to 2%), tremor (2%), hypesthesia (less than 1% to 2%), hallucinations (less than 1% to 1%), and vertigo (less than 1% to 1%) have been reported.
Gastrointestinal side effects including nausea (7% to 8%), dyspepsia (4% to 7%), abdominal pain (5% to 6%), anorexia (<1% to 2%), and colitis (1%) have been reported.
Musculoskeletal side effects including myalgia (5% to 7%) have been reported.
Ocular side effects including eye pain (4%) and abnormal vision (<1 to 2%) have been reported.
Genitourinary side effects including dysmenorrhea (2% to 4%) have been reported.
Other side effects including hyperacusis (2%), parosmia (<1% to 2%), and ear pain (<1% to 1%) have been reported.
Respiratory side effects including epistaxis (<1% to 1%) have been reported.
Metabolic side effects including peripheral edema (<1% to 1%) have been reported.
More zaleplon resources
- zaleplon Advanced Consumer (Micromedex) - Includes Dosage Information
- zaleplon MedFacts Consumer Leaflet (Wolters Kluwer)
- Zaleplon Prescribing Information (FDA)
- Zaleplon Professional Patient Advice (Wolters Kluwer)
- Zaleplon Monograph (AHFS DI)
- Sonata Consumer Overview
- Sonata Prescribing Information (FDA)
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