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Nabilone Side Effects

It is possible that some side effects of nabilone may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to nabilone: oral capsule

As well as its needed effects, nabilone may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking nabilone, check with your doctor or nurse as soon as possible:

  • Changes in mood
  • confusion
  • convulsions (seizures)
  • delusions
  • dizziness or fainting
  • fast or pounding heartbeat
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • mental depression
  • nervousness or anxiety
  • unusual tiredness or weakness (severe)
Symptoms of overdose
  • Difficulty in breathing
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • mental changes (severe)
  • nervousness or anxiety (severe)

Some nabilone side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Clumsiness or unsteadiness
  • drowsiness
  • dryness of mouth
  • false sense of well-being
  • headache
Less common or rare
  • Blurred vision or any changes in vision
  • dizziness or lightheadedness, especially when getting up from a lying or sitting position—more common with high doses
  • loss of appetite

For Healthcare Professionals

Applies to nabilone: oral capsule


Cardiovascular side effects have included orthostatic hypotension, hypotension, tachycardia, syncope, palpitation, flushing, hypertension, arrhythmia, and cerebral vascular accident.[Ref]


Dermatologic side effects have included anhidrosis, photosensitivity, pruritus, and rash.[Ref]


Endocrine side effects have included thirst.[Ref]


Gastrointestinal side effects have included dry mouth, nausea, anorexia, vomiting, diarrhea, abdominal pain, constipation, aphthous ulcer, mouth irritation, gastritis, and dyspepsia.[Ref]


Genitourinary side effects have included increased urination, decreased urination, hot flashes, urinary retention, and frequency of micturition.[Ref]


Hematologic side effects have included anemia and leukopenia.[Ref]


Immunologic side effects have included bacterial infection.[Ref]


Musculoskeletal side effects have included muscle pain, back pain, neck pain, joint pain, and unspecified pain.[Ref]


Ocular side effects have included vision disturbance, eye irritation, eye dryness, eye disorder, amblyopia, eye swelling, eyelid diseases, pupil dilation, photophobia, and visual field defect.[Ref]


Other side effects have included ear tightness, tinnitus, equilibrium dysfunction, fatigue, lightheadedness, coordination disturbance, asthesia, dysphoria, dizziness, twitch, irritability, fever, inhibited walking, unconsciousness, hypotonia, and face edema.[Ref]

Nervous system

Nervous system side effects have included drowsiness, vertigo, ataxia, decreased concentration, sedation, hallucinations, paresthesia, tremor, memory disturbance, perception disturbance, convulsions, dystonia, numbness, and akathisia.[Ref]


Respiratory side effects have included dyspnea, pharyngitis, nasal congestion, sinus headache, thick tongue, dry throat, dry nose, wheezing, nosebleed, cough, and voice change.[Ref]


Psychiatric side effects have included euphoria (feeling "high"), sleep disturbance, depression, confusion, disorientation, anxiety, depersonalization syndrome, speech disorder, abnormal dreams, insomnia, mood swings, inebriated feeling, toxic psychosis, paranoia, apathy, thought disorder, withdrawal, panic disorder, phobic neurosis, emotional disorder, and hyperactivity.[Ref]


1. "Product Information. Cesamet (nabilone)." Valeant Pharmaceuticals, Costa Mesa, CA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.