Inapsine Side Effects

Generic Name: droperidol

Note: This document contains side effect information about droperidol. Some of the dosage forms listed on this page may not apply to the brand name Inapsine.

Some side effects of Inapsine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to droperidol: injection injectable, injection solution

Along with its needed effects, droperidol (the active ingredient contained in Inapsine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking droperidol:

Less common
  • Anxiety
  • high blood pressure
  • restlessness
  • Fainting
  • fever
  • fixed upward position of the eyeballs
  • irregular or slow heart rate
  • spasm of the muscles of the tongue, face, neck, and back
  • sudden death

For Healthcare Professionals

Applies to droperidol: compounding powder, injectable solution


Frequency not reported: Hypotension, irregular cardiac rhythm, mild or moderate tachycardia, QT prolongation, serious arrhythmias (e.g., torsades de pointes), ventricular tachycardia, cardiac arrest, death (some of these side effects occurred in patients with no known risk factors, and some were associated with droperidol (the active ingredient contained in Inapsine) doses at or below recommended doses)

Nervous system

Unexplained fever, alteration of consciousness, extrapyramidal dysfunction, autonomic instability and elevated creatine kinase are all symptoms associated with neuroleptic agents. If these symptoms develop in patients receiving droperidol (the active ingredient contained in Inapsine) therapy, immediate discontinuation of the drug is warranted.

Extrapyramidal symptoms such as acute dystonia, parkinsonism, akathisia, and oculogyric crisis have been reported in patients receiving droperidol in doses as low as 0.65 mg. In addition, cases of akathisia have been reported in patients during epidural anesthesia.

Frequency not reported: Dysphoria, drowsiness, restlessness, hyperactivity, anxiety, hallucinations, dizziness, extrapyramidal symptoms, neuroleptic malignant syndrome, confusion, nervousness, paresthesia, somnolence, tremor, akathisia, oculogyric crisis, unexplained fever, alteration of consciousness, autonomic instability


Frequency not reported: pharyngitis, rhinitis, bronchospasm, laryngospasm (reported as rare)


Frequency not reported: Anaphylaxis (uncommon)


Frequency not reported : Injection site pain


Frequency not reported: Chills and/or shivering, tongue-swelling, sweating

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