Skip to Content

Atenolol / chlorthalidone Side Effects

Commonly reported side effects of atenolol/chlorthalidone include dizziness, fatigue, and cold extremities. Other side effects include bradycardia, and leg pain. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to atenolol / chlorthalidone: oral tablet

In addition to its needed effects, some unwanted effects may be caused by atenolol / chlorthalidone. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking atenolol / chlorthalidone:

More common
  • Cold arms or legs
  • difficult or labored breathing
  • shortness of breath
  • tightness in chest
  • wheezing
Less common
  • Chest pain or discomfort
  • chills
  • cold sweats
  • confusion
  • dizziness, faintness, or lightheadedness when getting up from lying or sitting position
  • leg pain
  • lightheadedness, dizziness, or fainting
  • slow or irregular heartbeat
  • unusual tiredness or weakness
Incidence not determined
  • Black, tarry stools
  • bleeding gums
  • blood in urine or stools
  • feeling that others are watching you or controlling your behavior
  • feeling that others can hear your thoughts
  • fever
  • general feeling of discomfort, illness, or weakness
  • paleness or cold feeling in fingertips and toes
  • pinpoint red spots on skin
  • seeing, hearing, or feeling things that are not there
  • severe mood or mental changes
  • skin irritation or rash, including rash that looks like psoriasis
  • tingling or pain in fingers or toes when exposed to cold
  • unusual behavior
  • unusual bleeding or bruising

If any of the following symptoms of overdose occur while taking atenolol / chlorthalidone, get emergency help immediately:

Symptoms of overdose
  • Blurred vision
  • decreased urination
  • dry mouth
  • increase in heart rate
  • muscle cramps or pain
  • numbness, tingling, pain, or weakness in hands or feet
  • rapid breathing
  • seizures
  • sunken eyes
  • sweating
  • thirst
  • trembling
  • weakness and heaviness of legs
  • wrinkled skin

Some of the side effects that can occur with atenolol / chlorthalidone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Discouragement
  • feeling sad or empty
  • irritability
  • lack of appetite
  • loss of interest or pleasure
  • tiredness
  • trouble concentrating
  • trouble sleeping
Less common
  • Diarrhea
  • feeling of constant movement of self or surroundings
  • nausea
  • sensation of spinning
  • unusual drowsiness, dullness, or feeling of sluggishness
Incidence not determined
  • Decreased interest in sexual intercourse
  • disturbed color perception
  • double vision
  • hair loss, thinning of hair
  • halos around lights
  • headache
  • inability to have or keep an erection
  • loss in sexual ability, desire, drive, or performance
  • loss of vision
  • night blindness
  • overbright appearance of lights
  • pain of penis on erection
  • tunnel vision

For Healthcare Professionals

Applies to atenolol / chlorthalidone: oral tablet


Atenolol-chlorthalidone is generally well tolerated. A postmarketing surveillance study of over 28,000 patients revealed that the incidence of any adverse event was less than 1%, except for dizziness (1.5%). Over an eight month study period, 3.1% of patients discontinued therapy due to side effects.[Ref]


In a prospective study of 83 patients who were taking daily doses of chlorthalidone 200 mg, 23 (28%) developed a decrease in serum potassium of at least 0.6 mEq/L. Maintenance of normal serum potassium levels during chlorthalidone therapy decreases the risk of arrhythmias, myopathy, hyponatremia and abnormal glucose metabolism.

The mechanism by which atenolol induces weight gain is unknown. Some investigators have reported a 4% to 9% reduction in total energy expenditure and a 25% reduction in thermogenic response to food during beta-blocker treatment.[Ref]

The metabolic side effects of chlorthalidone, as with other thiazide diuretics, may require electrolyte monitoring and/or potassium supplementation. Approximately 14% of patients develop hypokalemia during therapy. The risk of hypokalemia, hypomagnesemia, hyponatremia, and hypochloremia appears to be dose-related. Hypercalcemia and an increased serum bicarbonate may result from chlorthalidone diuresis.

Metabolic side effects of atenolol have included weight gain.[Ref]


A large, retrospective review of the use of atenolol-chlorthalidone revealed the incidence of bradycardia to be only 0.5%. Other cardiovascular side effects include hypotension, precipitation of heart failure, and cold extremities. Less than 1% of patients report flushing symptoms. These problems may limit the use of the combination product in some patients. Chlorthalidone can cause significant intravascular volume depletion and hypokalemia. Orthostatic hypotension and syncope have been reported rarely. Hypokalemia may induce or provoke arrhythmias in some patients.[Ref]

Atenolol-chlorthalidone-induced hypokalemia can rarely cause serious arrhythmias in otherwise healthy patients. It is recommended that the serum potassium concentration be kept within normal limits, especially in patients who are predisposed to arrhythmias.[Ref]


Hypersensitivity reactions to thiazide diuretics usually involve the skin. Thiazides and the chemically related drug, chlorthalidone, have been implicated as the cause of necrotizing vasculitis, psoriasiform eruptions, and pseudoporphyria (bullous photosensitive lesions) in rare cases. Rare cases of cutaneous vasculitis and psoriasiform eruptions have been associated with atenolol.[Ref]


Genitourinary problems associated with atenolol and chlorthalidone as monotherapy include impotence in up to 14% and 42% of male patients, respectively. However, a large, retrospective study revealed a 0.6% incidence of impotence associated with the combination, atenolol-chlorthalidone. Decreased sexual arousal and orgasm have rarely been reported by female patients.[Ref]

The etiology of sexual dysfunction associated with chlorthalidone is not known. One study of 19 middle-aged hypertensive men showed no significant decrease in serum zinc or testosterone levels relative to a control group of 31 unmedicated middle-aged normotensive men. While sexual dysfunction was reported in 42% of treated men on chlorthalidone alone (compared to 16% in the control group), serum testosterone and zinc levels were actually higher in the treated group, and were highest in the men on the highest dose of chlorthalidone.[Ref]

Nervous system

Rare cases of acute visual loss have been associated with atenolol and atenolol-chlorthalidone. In some cases, there was evidence of retinal arteriolar spasm. At least one affected patient did well on atenolol alone after discontinuation of the combination product.[Ref]

Nervous system-related complaints of depression, headache, fatigue, and sleep disturbances each occur in approximately 2% to 20% of patients. Fatigue and insomnia, however, have been reported in up to 50% of patients on atenolol monotherapy.[Ref]


The respiratory system is usually not affected by atenolol because it is relatively specific for beta-1-adrenergic receptors. However, at higher doses, and sometimes even at usual doses, atenolol may block beta-2-adrenergic receptors. Such blockade can result in dyspnea or wheezing, particularly in patients with a history of reactive airways disease.[Ref]


Chlorthalidone has been associated with increases in total serum cholesterol, triglycerides, and LDL cholesterol.

At least one case of severe glucose intolerance, resulting in hyperosmolar hyperglycemic nonketotic coma, has been associated with chlorthalidone. The patient did not have diabetes, had a normal fasting blood glucose prior to chlorthalidone therapy, and did well on no antidiabetic medications after resolution of the acute episode of hyperglycemia. Infection and myocardial infarction were ruled out.

A 38-year-old woman with hypertension developed oligomenorrhea, then galactorrhea associated with a significantly elevated serum prolactin while taking atenolol. Head CT scan was negative for a pituitary tumor. The serum prolactin level returned to baseline and the patient's symptoms resolved within two months after discontinuation of the drug. Rechallenge was refused.[Ref]

Endocrinologic abnormalities related to chlorthalidone, and other thiazide diuretics, include decreased glucose tolerance and adverse effects on lipid profiles. Atenolol may increase serum triglycerides. Such increases may be important in some patients with a history of diabetes or coronary artery disease. A rare case of hyperprolactinemia with galactorrhea has been associated with atenolol. Beta-blockers can mask signs and symptoms of hypoglycemia (sweating and tachycardia) and hyperthyroidism.

Among patients with hyperthyroidism, atenolol has been reported to have decreased T3 concentrations slightly (but did not change T4 concentrations).[Ref]


New or worsened renal insufficiency may develop if patients become too dehydrated. Chlorthalidone has been associated with mild decreases in urine concentrating ability and renal plasma flow, suggestive of interference with renal tubular function.[Ref]


A 68-year-old woman with hypertension developed vomiting, abdominal pain, and progressive renal failure associated with extensive retroperitoneal fibrosis and urethral obstruction. While the patient was also taking oral iron preparations, metoclopramide, and ibuprofen, the authors of this case report implicated atenolol due to previous associations of retroperitoneal fibrosis to other beta-blockers.[Ref]

Gastrointestinal problems are generally mild. Approximately 5% to 10% of patients on chlorthalidone monotherapy complain of nausea, vomiting, abdominal cramping, diarrhea, or constipation. A large, retrospective study of over 28,000 patients who received atenolol-chlorthalidone reported none of these complaints in more than 1% of patients. Rare cases of retroperitoneal fibrosis have been associated with some beta-blockers, including atenolol.[Ref]


Psychiatric problems associated with beta-blockers include depression. Rare cases of acute psychosis have been associated with atenolol.[Ref]


Rare hematologic side effects have been associated with chlorthalidone, including neutropenia, agranulocytosis, thrombocytopenia, and aplastic anemia.[Ref]

A 63-year-old man with hypertension, ischemic heart disease, chronic bronchitis, and type II diabetes mellitus was stable on multiple medications until chlorthalidone was substituted for hydrochlorothiazide. Within three weeks of initiation of chlorthalidone, the patient developed a diffuse, upper extremity pruritic rash, fever, dyspnea, malaise, and fatigue associated with a peripheral leukocyte count of 2,000/mm3. Bone marrow aspiration revealed hypocellularity of the myeloid line only. Within nine days after stopping chlorthalidone, the patient's leukocyte count returned to normal. No other cause of neutropenia was discovered. The presence of an antineutrophil antibody was not proven.[Ref]


Hepatic injury associated with either drug is rare. Cases of acute hepatic cholestasis have been associated with atenolol.[Ref]

A 73-year-old man with hypertension developed pruritus and right upper quadrant abdominal pain associated with elevated serum liver function tests within nine months after switching from methyldopa to atenolol. Liver biopsy revealed canalicular and centrolobular cholestasis. No other etiology was found. The patient's signs and symptoms of hepatitis resolved within one to four weeks after stopping atenolol. Rechallenge was not done.[Ref]


Musculoskeletal weakness and cramps have each been reported in up to 7% of patients on chlorthalidone monotherapy. Chlorthalidone-induced hypokalemia has resulted in hypokalemic myopathy in rare cases.[Ref]

Cases of progressive generalized paralysis associated with chlorthalidone-induced hypokalemia have been reported. In some of these cases, muscle histology was remarkable for vacuolar degeneration.[Ref]


The mechanism of myopia is unknown. There is evidence of an allergic reaction in which the ciliary body may become edematous, and evidence of a direct disturbance by chlorthalidone of the normal salinity of the lens. Either effect may alter the refractive index. In some cases, ultrasonography of affected eyes has shown a difference both in the anterior chamber depth and in the lens thickness during chlorthalidone therapy.[Ref]

A rare ocular side effect, transient myopia, has been associated with chlorthalidone.[Ref]


A 64-year-old woman with hypertension developed fever and chest pain associated with pericardial effusion, progressive renal dysfunction, and elevated serum anti-IgG antibodies while taking atenolol. The signs and symptoms of the syndrome resolved two months after discontinuation of the drug.[Ref]

Immunologic effects associated with atenolol include a single report of drug-induced systemic lupus erythematosus.[Ref]


1. Maxwell MH, Garrett BN, Saunders E, Schnaper H "Postmarketing survey of the effects of an atenolol / chlorthalidone combination in the treatment of hypertension." Clin Ther 9 (1987): 380-9

2. Morrissette DL, Skinner MH, Hoffman BB, Levine RE, Davidson JM "Effects of antihypertensive drugs atenolol and nifedipine on sexual function in older men: a placebo-controlled, crossover study." Arch Sex Behav 22 (1993): 99-109

3. Disler LJ, Joffe BI, Seftel HC "Massive hypertriglyceridemia associated with atenolol." Am J Med 85 (1988): 586-7

4. Papademetriou V, Fletcher R, Khatri IM, Freis ED "Diuretic-induced hypokalemia in uncomplicated systemic hypertension: effect of plasma potassium correction on cardiac arrhythmias." Am J Cardiol 52 (1983): 1017-22

5. Jensen OB, Mosdal C, Reske-Nielsen E "Hypokalemic myopathy during treatment with diuretics." Acta Neurol Scand 55 (1977): 465-82

6. Fichman MP, Vorherr H, Kleeman CR, Telfer N "Diuretic-induced hyponatremia." Ann Intern Med 75 (1971): 853-63

7. Palmer FJ "Letter: Chlorthalidone-induced hypercalcemia." JAMA 229 (1974): 267

8. Curtis J, Horrigan F, Ahearn D, Varney R, Sandler SG "Chlorthalidone-induced hyperosmolar hyperglycemic nonketotic coma." JAMA 220 (1972): 1592-3

9. Navarro RP, O'Brien DK, Nuffort P, Spencer DL "Diuretic induced hypokalemia in the elderly." J Fam Pract 14 (1982): 685-9

10. Chowdhury FR, Bleicher SJ "Chlorthalidone--induced hypokalemia and abnormal carbohydrate metabolism." Horm Metab Res 2 (1970): 13-6

11. Landmann-Suter R, Struyvenberg A "Initial potassium loss and hypokalaemia during chlorthalidone administration in patients with essential hypertension: the influence of dietary sodium restriction." Eur J Clin Invest 8 (1978): 155-64

12. Kuller L, Farrier N, Caggiula A, Borhani N, Dunkle S "Relationship of diuretic therapy and serum magnesium levels among participants in the Multiple Risk Factor Intervention Trial." Am J Epidemiol 122 (1985): 1045-59

13. Cembrowski GS, Huntington RW, 3d "Probable fatal cardiac dysrhythmia secondary to diuretic-induced hypokalemia." Am J Forensic Med Pathol 2 (1981): 243-8

14. Berg KJ, Gisholt K, Wideroe TE "Potassium deficiency in hypertensives treated with diuretics. Analysis of three alternative treatments by an oral test for potassium deficiency." Eur J Clin Pharmacol 7 (1974): 401-5

15. Mozes B, Pines A, Werner D, Olchovsky D, Lieberman P, Frankl O "Thiazide-induced hyponatremia: an unusual neurologic course." South Med J 79 (1986): 629-31

16. Remenchik AP, Johnston LC "Potassium depletion produced by administration of chlorthalidone to nonedematous patients with arterial hypertensin." Am J Med Sci 252 (1966): 171-6

17. Perry HM, Jr "Some wrong-way chemical changes during antihypertensive treatment: comparison of indapamide and related agents." Am Heart J 106 (1983): 251-7

18. Falch DK, Schreiner AM "Changes in urinary electrolytes versus serum electrolytes during treatment of primary hypertension with chlorthalidone alone and in combination with spironolactone." Acta Med Scand 209 (1981): 111-4

19. Taylor FR "Weight change associated with the use of migraine-preventive medications." Clin Ther 30 (2008): 1069-80

20. Sumiye L, Vivian AS, Frisof KB, Podany EC "Potassium loss associated with hydrochlorothiazide versus chlorthalidone." Clin Ther 4 (1981): 308-20

21. Odugbesan O, Chesner IM, Bailey G, Barnett AH "Hazards of combined beta-blocker/diuretic tablets ." Lancet 1 (1985): 1221-2

22. Bowman CA, Jeffcoate WJ "Severe salt and water deficiency associated with a combination of atenolol and chlorthalidone." BMJ 297 (1988): 742-3

23. Carney SL, Morgan TO "Diuretic-induced hypokalemia and altered renal function." Int J Clin Pharmacol Ther Toxicol 24 (1986): 665-7

24. Cosenzi A, Sacerdote A, Bocin E, Molino R, Mangiarotti M, Bellini G "Metabolic effects of atenolol and doxazosin in healthy volunteers during prolonged physical exercise." J Cardiovasc Pharmacol 25 (1995): 142-6

25. Katz FH, Eckert RC, Gebott MD "Hypokalemia caused by surreptitious self-administration of diuretics." Ann Intern Med 76 (1972): 85-90

26. Stewart DE, Ikram H, Espiner EA, Nicholls MG "Arrhythmogenic potential of diuretic induced hypokalaemia in patients with mild hypertension and ischaemic heart disease." Br Heart J 54 (1985): 290-7

27. Brown HC, Carruthers SG, Johnston GD, et al "Clinical pharmacologic observations on atenolol, a beta-adrenoceptor blocker." Clin Pharmacol Ther 20 (1976): 524-34

28. "Product Information. Thalitone (chlorthalidone)." Monarch Pharmaceuticals Inc, Bristol, TN.

29. Obel AO "Efficacy and tolerability of long term oxprenolol and chlorthalidone singly and in combination in hypertensive blacks." Jpn Heart J 31 (1990): 183-92

30. Wadsworth AN, Murdoch D, Brogden RN "Atenolol: a reappraisal of its pharmacological properties and therapeutic use in cardiovascular disorders." Drugs 42 (1991): 468-510

31. Totterman K, Groop L, Groop PH, et al "Effect of beta-blocking drugs on beta-cell function and insulin sensitivity in hypertensive non-diabetic patients." Eur J Clin Pharmacol 26 (1984): 13-7

32. Rossner S, Weiner L "Atenolol and metoprolol: comparison of effects on blood pressure and serum lipoproteins, and side effects." Eur J Clin Pharmacol 24 (1983): 573-7

33. MacGregor GA, Tasker PR, de Wardener HE "Diuretic-induced oedema." Lancet 1 (1975): 489-92

34. Giang DW, Isaeff DM "Atenolol overdosage in a patient with progressive renal failure." West J Med 145 (1986): 101-3

35. Abrahamsen AM, Digranes O, Gisholt K "Comparison of the side-effects of pindolol and atenolol in the treatment of hypertension." J Intern Med 228 (1990): 219-22

36. Valimaki M, Maass L, Harno K, Nikkila EA "Lipoprotein lipids and apoproteins during beta-blocker administration: comparison of penbutolol and atenolol." Eur J Clin Pharmacol 30 (1986): 17-20

37. Fitzgerald JD, Ruffin R, Smedstad KG, et al "Studies on the pharmacokinetics and pharmacodynamics of atenolol in man." Eur J Clin Pharmacol 13 (1978): 81-9

38. Burris JF, Davidov ME, Jenkins P, Rofman B, Ginsberg D, Rosenbaum R, Ryan JR, Jain AK, Mroczek WJ "Comparison of the antihypertensive effects of betaxolol and chlorthalidone as monotherapy and in combination." Arch Intern Med 149 (1989): 2437-41

39. Frishman WH "Atenolol and timolol, two new systemic beta-adrenoceptor antagonists." N Engl J Med 306 (1982): 1456-62

40. Perry HM, Hall WD, Benz JR, Bartels DW, Kostis JB, Townsend RR, Due DL, Peng A, Sirgo M "Efficacy and safety of atenolol, enalapril, and isradipine in elderly hypertensive women." Am J Med 96 (1994): 77-86

41. Kuller LH, Hulley SB, Cohen JD, Neaton J "Unexpected effects of treating hypertension in men with electrocardiographic abnormalities: a critical analysis." Circulation 73 (1986): 114-23

42. Kholeif M, Isles C "Profound hypotension after atenolol in severe hypertension." Br Med J 298 (1989): 161-2

43. Bjornberg A, Gisslen H "Thiazides: A cause of necrotising vasculitis?" Lancet 2 (1965): 982-3

44. Pallin O, Ericsson R "Ultrasound studies in a case of hygroton-induced myopia." Acta Ophthalmol (Copenh) 43 (1965): 692-6

45. Gawkrodger DJ, Beveridge GW "Psoriasiform reaction to atenolol." Clin Exp Dermatol 9 (1984): 92-4

46. Wolf R, Ophir J, Elman M, Krakowski A "Atenolol-induced cutaneous vasculitis." Cutis 43 (1989): 231-3

47. Smith N "Acute stomatitis medicamentosa. Two case reports." Aust Dent J 23 (1978): 305-7

48. Baker EJ, Reed KD, Dixon SL "Chlorthalidone-induced pseudoporphyria: clinical and microscopic findings of a case." J Am Acad Dermatol 21 (1989): 1026-9

49. Dimenas E, Dahlof C, Olofsson B, Wiklund I "CNS-related subjective symptoms during treatment with beta1-adrenoceptor antagonists (atenolol, metoprolol): two double-blind placebo controlled studies." Br J Clin Pharmacol 28 (1989): 527-34

50. Stessman J, Ben-Ishay D "Chlorthalidone-induced impotence." Br Med J 281 (1980): 714

51. Geissler AH, Turnlund JR, Cohen RD "Effect of chlorthalidone on zinc levels, testosterone, and sexual function in man." Drug Nutr Interact 4 (1986): 275-83

52. Wassertheil-Smoller S, Oberman A, Blaufox MD, Davis B, Langford H "The Trial of Antihypertensive Interventions and Management (TAIM) Study. Final results with regard to blood pressure, cardiovascular risk, and quality of life." Am J Hypertens 5 (1992): 37-44

53. Snaith RP, McCoubrie M "Antihypertensive drugs and depression." Psychol Med 4 (1974): 393-8

54. Deckert J, Przuntek H, Gleiter CH "Organic anxiety syndrome after withdrawal of atenolol." Am J Psychiatry 151 (1994): 1840

55. Arber N "Delirium induced by atenolol." Br Med J 297 (1988): 1048

56. Viadero JJ, Wong SH, White WB "Acute psychotic behavior associated with atenolol." Am J Psychiatry 140 (1983): 1382

57. Patterson JF "Pseudoakathisia associated with atenolol." J Clin Psychopharmacol 6 (1986): 390

58. Foerster EC, Greminger P, Siegenthaler W, Vetter H, Vetter W "Atenolol versus pindolol: side-effects in hypertension." Eur J Clin Pharmacol 28 (1985): s89-91

59. Volmink J "Atenolol and visual loss." S Afr Med J 81 (1992): 433

60. van Zyl AI, Jennings AA, Bateman ED, Opie LH "Comparison of respiratory effects of two cardioselective beta-blockers, celiprolol and atenolol, in asthmatics with mild to moderate hypertension." Chest 95 (1989): 209-13

61. Andersen OO, Persson I "Carbohydrate metabolism during treatment with chlorthalidone and ethacrynic acid." Br Med J 2 (1968): 798-801

62. Lee ST "Hyperprolactinemia, galactorrhea, and atenolol." Ann Intern Med 116 (1992): 522

63. Ames RP, Hill P "Increase in serum-lipids during treatment of hypertension with chlorthalidone." Lancet 1 (1976): 721-3

64. Ahmad S "Atenolol and retroperitoneal fibrosis." South Med J 83 (1990): 1367

65. Eckhauser ML, Dokler M, Imbembo AL "Diuretic-associated pancreatitis: a collective review and illustrative cases." Am J Gastroenterol 82 (1987): 865-70

66. Doherty CC, McGeown MG, Donaldson RA "Retroperitoneal fibrosis after treatment with atenolol." Br Med J 2 (1978): 1786

67. Schwartz MS, Frank MS, Yanoff A, Morecki R "Atenolol-associated cholestasis." Am J Gastroenterol 84 (1989): 1084-6

68. Lewis MJ, Jones DM, Dart AM, Henderson AH "The psychological side effects of acebutolol and atenolol." Br J Clin Pharmacol 17 (1984): 364-6

69. Lichter I, Richardson PJ, Wyke MA "Differential effects of atenolol and enalapril on memory during treatment for essential hypertension." Br J Clin Pharmacol 21 (1986): 641-5

70. Writer ST, Stevens DL, Starkebaum G "Chlorthalidone-associated neutropenia." West J Med 136 (1982): 59-61

71. Oh SJ, Douglas JE, Brown RA "Hypokalemic vacuolar myopathy associated with chlorthalidone treatment." JAMA 216 (1971): 1858-9

72. Stennis SD "Drug-induced myopia: a case report." Am J Optom Physiol Opt 53 (1976): 422-3

73. D'Alena P, Robinson M "Hygroton-induced myopia." Calif Med 110 (1969): 134-5

74. Henderson CA, Shamy HK "Atenolol-induced pseudolymphoma." Clin Exp Dermatol 15 (1990): 119-20

75. Gouet D, Marechaud R, Aucouturier P, et al "Atenolol induced systemic lupus erythematosus syndrome." J Rheumatol 13 (1986): 446-7

Not all side effects for atenolol / chlorthalidone may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.