Generic name: NITROFURANTOIN 25mg in 5mL
Dosage form: oral suspension
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Furadantin should be given with food to improve drug absorption and, in some patients, tolerance.
50-100 mg four times a day -- the lower dosage level is recommended for uncomplicated urinary tract infections.
5-7 mg/kg of body weight per 24 hours, given in four divided doses (contraindicated under one month of age).
The following table is based on an average weight in each range receiving 5 to 6 mg/kg of body weight per 24 hours, given in four divided doses. It can be used to calculate an average dose of Furadantin Oral Suspension (25 mg/5mL) for pediatric patients.
|Weight in Kilograms (kg)||Pediatric Doses (milliliters) and Frequency|
|7 kg to 11 kg||2.5 mL Four times Daily|
|12 kg to 21 kg||5 mL Four times Daily|
|22 kg to 30 kg||7.5 mL Four times Daily|
|31 kg to 41 kg||10 mL Four times Daily|
|42 kg or greater||See Adult Dose|
Therapy should be continued for one week or for at least 3 days after sterility of the urine is obtained. Continued infection indicates the need for reevaluation.
For long-term suppressive therapy in adults, a reduction of dosage to 50-100 mg at bedtime may be adequate. For long-term suppressive therapy in pediatric patients, doses as low as 1 mg/kg per 24 hours, given in a single dose or in two divided doses, may be adequate. SEE WARNINGS SECTION REGARDING RISKS ASSOCIATED WITH LONG TERM THERAPY.