User Reviews for Zonisamide

Also known as: Zonegran

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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15%(1)
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Zonisamide review summary

8.0/10 Average Rating

7 Ratings with 9 User Reviews

Compare all 31 medications used in the treatment of Migraine Prevention.

Reviews for Zonisamide to treat Migraine Prevention

Review by What memory:

User Rating:  
   
7.0

Zonegran (zonisamide): I took Topamax for a while and it worked wonders but the side effects were insane. However, the zonesamide works very well for preventing my migraines. I take 400 mg a day. Word finding and memory, I don't even know what those are anymore. However, I was living in constant pain. Nothing was working for me. This is the only thing that has done anything for me in years.

12 users found this comment helpful. Did you?   Yes   No Report as inappropriate

January 12, 2014 1:29 AM

Review by Migrainemandy (taken for 1 to 2 years):

User Rating:  
   
10

I started having migraines suddenly two years after the birth of my first and only child. Sought help from a Neurologist eventually when anti-depressants prescribed by my family practice Dr didn't work. My Neuro doctor started me out on Topamax first, which I had terrible side effects from: word recall was awful and I felt paranoid and edgy all the time. Zonisamide has been a game changer. So far limited side effects: some dizziness - not bad, rash on my upper arm - not a big deal. I'll take this in exchange for the life altering migraines that pretty much shut me down any day!

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August 29, 2013 10:55 AM

Review by bobbi28 (taken for less than 1 month):

I did experience some appetite loss at 1st, which was OK because I wanted to loss about 5 pounds-but I started gaining weight, face was puffy, while eating very little and no decrease in exercise. The worst, however, was the onset of depression and feeling of hopelessness. I was up to 100 mg a day, on it for 2-3 weeks, and stopped cold turkey. Taking Topamax, years ago, did help with headaches and I lost weight (actually too much in beginning but body adjusted) but I also lost word facility. Not good trade off so I had to go off Topamax. Help!

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April 20, 2013 2:50 PM

Review by Anonymous (taken for 2 to 5 years):

User Rating:  
   
9.0

Zonegran (zonisamide): I don't notice any side effects compared to some of the other anti-seizure medicines.

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October 25, 2012 5:57 PM

Review by Anonymous:

User Rating:  
   
8.0

I have chronic headaches (>15 per month) and tried many treatments that did not help: Botox, Topamax, and others. With zonisamide my headaches are mostly limited to just the week before my period.

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April 12, 2012 5:55 PM

Review by Still Looking:

User Rating:  
   
9.0

Zonegran (zonisamide): I've been taking Zonegran for a few years now at 300mg per day. It had really gotten my headaches under control to where I would only have a headache periodically. Weight loss has been a side effect that I haven't minded. The problem is I've had significant memory and focus issues. I hardly felt competent most of the time. I have slowly weened myself down to 100mgs per day (I notified my neurologist of this because its an anti-seizure medicine so you shouldn't stop it cold turkey or it could cause a seizure). My memory has improved significantly, but the headaches have returned with a vengeance. I'm back to taking narcotics to address each debilitating headache. I used to take Topamax. It too worked beautifully, but also wiped out the memory.

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January 4, 2012 5:36 PM

Review by Anonymous:

User Rating:  
   
7.0

Zonegran (zonisamide): On 50 mg and have seen a huge improvement in my migraines. Down to 5 per month.

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November 28, 2011 1:23 PM

Review by Zonegran User:

User Rating:  
   
6.0

Zonegran (zonisamide): I have used Zonegran for headaches only. It is the only thing that seems to have lessened them somewhat, but I still have headaches and they affect me cognitively. I'm mentally slower, have word-finding problems, my memory is bad, and my attention is terrible. I've tried to go off it on occasion, but my headaches get absolutely awful, so I stay on it.

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March 30, 2011 3:42 PM

Review by Anonymous:

Zonegran (zonisamide): I just got put on this medication for migraines. I took Topamax in the past but side effects were way too much for me.

25 users found this comment helpful. Did you?   Yes   No Report as inappropriate

March 19, 2011 8:07 PM

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