User Reviews for Zonisamide

Also known as: Zonegran

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Zonisamide.

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Reviews for Zonisamide to treat Migraine Prevention

Review by bobbi28 (taken for less than 1 month):

zonisamide: I did experience some appetite loss at 1st, which was OK because I wanted to loss about 5 pounds-but I started gaining weight, face was puffy, while eating very little and no decrease in exercise. The worst, however, was the onset of depression and feeling of hopelessness. I was up to 100 mg a day, on it for 2-3 weeks, and stopped cold turkey. Taking Topamax, years ago, did help with headaches and I lost weight (actually too much in beginning but body adjusted) but I also lost word facility. Not good trade off so I had to go off Topamax. Help!

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April 20, 2013 2:50 PM
Review by Anonymous (taken for 2 to 5 years): User Rating:  
   
9.0

Zonegran (zonisamide): I don't notice any side effects compared to some of the other anti-seizure medicines.

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October 25, 2012 5:57 PM
Review by Anonymous: User Rating:  
   
8.0

zonisamide: I have chronic headaches (>15 per month) and tried many treatments that did not help: Botox, Topamax, and others. With zonisamide my headaches are mostly limited to just the week before my period.

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April 12, 2012 5:55 PM
Review by Still Looking: User Rating:  
   
9.0

Zonegran (zonisamide): I've been taking Zonegran for a few years now at 300mg per day. It had really gotten my headaches under control to where I would only have a headache periodically. Weight loss has been a side effect that I haven't minded. The problem is I've had significant memory and focus issues. I hardly felt competent most of the time. I have slowly weened myself down to 100mgs per day (I notified my neurologist of this because its an anti-seizure medicine so you shouldn't stop it cold turkey or it could cause a seizure). My memory has improved significantly, but the headaches have returned with a vengeance. I'm back to taking narcotics to address each debilitating headache. I used to take Topamax. It too worked beautifully, but also wiped out the memory.

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January 4, 2012 5:36 PM
Review by Anonymous: User Rating:  
   
7.0

Zonegran (zonisamide): On 50 mg and have seen a huge improvement in my migraines. Down to 5 per month.

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November 28, 2011 1:23 PM
Review by Zonegran User: User Rating:  
   
6.0

Zonegran (zonisamide): I have used Zonegran for headaches only. It is the only thing that seems to have lessened them somewhat, but I still have headaches and they affect me cognitively. I'm mentally slower, have word-finding problems, my memory is bad, and my attention is terrible. I've tried to go off it on occasion, but my headaches get absolutely awful, so I stay on it.

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March 30, 2011 3:42 PM
Review by Anonymous:

Zonegran (zonisamide): I just got put on this medication for migraines. I took Topamax in the past but side effects were way too much for me.

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March 19, 2011 8:07 PM

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