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Trazodone for Depression User Reviews (Page 3)

Trazodone has an average rating of 6.7 out of 10 from a total of 129 reviews for the treatment of Depression. 58% of reviewers reported a positive experience, while 28% reported a negative experience.

Reviews for Trazodone

  • Thales
  • Taken for 1 to 6 months
  • April 27, 2024

"I'm a 26-year-old man, a medical student, who has been fighting depression since adolescence. I've been on almost all SSRIs as a monotherapy, and none of them worked well, except for Paroxetine, which worked for 5 years. Then I switched to Escitalopram, which helped, but did not take away my depression and anxiety. Now, after all this struggle, my psychiatrist finally found a combination of drugs that worked great for me: Trazodone 100mg per day + Escitalopram 30mg per day. This combo has been a miracle. I'm very good, my thinking is clear, and I'm able to focus and learn more. Plus, the anxiety and depression are gone. I hope I stay this way for a very long time and hope that this combo keeps working for a very long time. Side effects of trazodone were only present in the first few weeks: sedation, somnolence, and weird dreams. I recommend taking it before sleep."

10 / 10
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6 Report
  • Worry...
  • Taken for 1 to 6 months
  • August 6, 2019

"It's a good drug for anxious depression and great for sleep. I couldn't tolerate but just 10 mg Prozac because of agitation, but now 50 mg trazodone nightly and 10 mg Prozac morning gives me smooth depression relief."

9 / 10
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39 Report
  • user...
  • October 29, 2010

Oleptro (trazodone) "I took 1/2 of 150 mg Oleptro for 4 days and had the worst experience of my life. After the first dose, I slept for 19 hours and still woke feeling heavily medicated. After two cups of coffee and a meal, I was able to stay awake for five hours but was not totally coherent. I took another 1/2 pill at bedtime and slept without waking until 10:00 the next morning. During all of this 'rest,' I had the strangest dreams. Not nightmares, but they left me feeling bad and confused. I was able to stay awake and plant flowers, but still felt drugged. I also had an overwhelming feeling of sadness that brought me to tears. Monday morning, I woke up vomiting with severe stomach pains. My vision became more blurred with each day. I have been out of work for a week."

1 / 10
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81 Report

Frequently asked questions

  • Sucke...
  • Taken for 1 to 6 months
  • February 14, 2013

Oleptro (trazodone) "It gave me restless, crawly legs on 50 mg. It was very sedating 12 weeks ago. I broke it in half, and that worked for 4 weeks, then no sedation at all and bad night sweats. It made me very foggy the following day, and I had palpitations half the time. I also experienced hangover headaches."

1 / 10
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68 Report
  • Shifty
  • Taken for 1 to 6 months
  • July 3, 2019

"I take this as a mood enhancer/sleep aid alongside my antidepressant, Zoloft. Within an hour of taking this medication, I need to sleep. If I wake up within 3 hours of taking it, I get extremely dizzy and begin to stumble around. If I do manage to sleep after waking up, I wake up with a terrible headache and brain fog. If I don’t wake up after taking this medication, I sleep very soundly but still wake up a bit disoriented (brain fog)."

8 / 10
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37 Report

Are you taking this medicine?

  • Nic
  • Taken for 1 to 2 years
  • August 25, 2020

"I was put onto Trazadone 100mg after Fluoxetine stopped working and while I felt better for the first few weeks, it turned me into an absolute monster. I couldn't control my emotions, got unnecessarily angry and irritated at even the smallest things that would normally go right over my head and completely took away my sex drive and induced panic attacks. Finally decided to come off it a month ago and I feel like I've got myself back again finally, even my family have commented on how I'm my old self again. Do NOT recommend!"

1 / 10
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29 Report
  • A9S7
  • January 24, 2018

"I've been struggling with severe anxiety and depression for almost 5 years now, (I'm 21), and the first week (on 50 mg) was AWFUL. Fast forward to the next week, and for the first time in a long time, I started to feel like a human again. Getting out of bed became easier, and my motivation to do my schoolwork came back! I've noticed that sometimes I'll be in a good mood, and I'll feel myself get overly happy? Hard to explain, but it's better than having suicidal thoughts on an almost daily basis, am I right? It helped with my anxiety-related insomnia a bit, and the amount of anxiety attacks I'd have per day has decreased (but my anxiety is still pretty bad). Thinking of asking my doc to up the dosage?"

8 / 10
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42 Report

More FAQ

  • Nezra
  • Taken for 6 months to 1 year
  • April 27, 2017

"I am a 50-year-old struggling through the initial stages of menopause. The hot flashes and insomnia have been miserable, and HRT is not an option. My GP recommended trazodone, and I am so grateful! The hot flashes seem to be cyclical with me, so I can go months with no issues, and then they come back, so I only use trazodone at the height of sleep disruption. I usually can take 25 mg, and it works fine, other times, I take 50 mg. It takes about an hour for it to kick in, and I sleep through the hot flashes, which are every 30 minutes. I love this medication, and it is so inexpensive!"

10 / 10
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45 Report
  • Anonymous
  • January 12, 2012

"Being acutely depressed to the point of suicidal ideation, I was given Trazodone and have had no noticeable negative side effects. I am on a maintenance program due to post-traumatic stress disorder and have been for 4 years."

9 / 10
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65 Report
  • Anonymous
  • February 1, 2016

"It was a negative experience for me at least. I felt sad, depressed, can't sleep, and aggressive toward myself and hate dislike who I am. I don't think my Dr. listens to me or maybe it's my fault. I cry at work and so scared I'll lose my job, I'm so scared and anxious and depressed, and the medicine makes me feel a lot worse."

1 / 10
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48 Report
  • Anonymous
  • August 5, 2011

"I have been taking trazodone for about 8 weeks and the first 3-5 weeks were fairly rough. I felt dizzy standing up, had bad headaches, and nausea, especially just after taking the medicine. However, it is a wonder, helping me fall off to sleep. 9 times out of 10, I'm out in 15 minutes and in a very deep sleep, nothing will wake me for 8-9 hours. As long as you put your head down and close your eyes! If you stay awake, you will feel terrible and very sick! The past week, I have noticed anxiety has reduced and my mood has improved slightly. My motivation is still pretty low. However, I had terrible side effects on several previous medicines and ended up in the hospital with some nasty ones! A few dizzy spells for a few weeks is pretty good really!"

7 / 10
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64 Report
  • keep...
  • Taken for 10 years or more
  • October 20, 2013

"I take Effexor, Lamictal, Ativan, which are not helping too much. My doc gave me Trazodone to help with sleeping. I feel very groggy when waking up. It's not helping me with depression, but helps me sleep."

1 / 10
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56 Report
  • Recov...
  • June 11, 2019

"I started trazodone 150 mg to treat anxiety and depression 9 weeks ago. I’m still feeling awful and have bad anxiety, terrible mood swings, emotional, I get a horrible feeling after I’ve taken it, like I’m on drugs. It definitely helps me sleep, totally knocks me out! So I take it just before bed. Mornings awful, like having a terrible hangover, and I’m in recovery 15 months free from booze and cocaine. My doc advised me to increase to 300 mg. I tried that for 2 days, side effects were awful: hideous diarrhea and panicky. I’m now on week 10, and this isn’t subsiding. I’ve been told to drop back down to 150 mg. Will this improve? Anyone experienced similar, pushed through, and got a different result? I trust my GP, but I’m not sure how long I can continue to feel like this. I'm so panicked and awful. All day I feel confused, dizzy, mix my words up, forget everything. I’m also on a reduction from diazepam, that is nearly gone."

2 / 10
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32 Report
  • kaboom...
  • Taken for 1 to 6 months
  • February 19, 2019

"I have finished my first month of 150 mg Trazodone after a heroin addiction to help with depression and insomnia. Getting up is a lot easier in the mornings, I wasn't able to function due to depression, but now things are getting a little bit better. Mostly at night is when poop hits the fan for me mentally. I have BPD as well, which trazodone has 0% effect on. Doctors don't really care about my health, they just gave it to me because I asked, and I was on this milligram prior to addiction. I think I got hooked on heroin again because I was off my SARI. Anyways, chin up. This stuff isn't too terrible. I can fall asleep fast and quick and not want to die all day, so that's something."

7 / 10
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33 Report
  • VOR
  • January 29, 2016

"My PCM prescribed it for hot flashes because I can't take anything with estrogen, so no HRT for me. I was having 10-12 hot flashes in a 24-hour period. Now I only have 2-3. I must take it at night because it definitely helps with sleep. I still wake up slightly groggy. And if I have a hot flash, it does wake me, but I'm able to go back to sleep. I started with 50 mg, but now I take 25. I may try to take it every other night because I don't like being on medication. But I am pleased with it. It is also an older drug, so any bad side effects should've been discovered by now."

9 / 10
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45 Report
  • DeNeese
  • December 18, 2010

"I was put on Trazodone for depression after other antidepressants began giving me restless legs syndrome. It has been great for both sleep and depression. I am having side effects of a stuffy nose and sore muscles. Also having some loss of bladder control when I sneeze or cough from it. Overall, it has been the best one I have tried so far for depression. It lets me sleep, whereas before I would have nonstop thoughts keeping me awake."

10 / 10
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60 Report
  • anore...
  • Taken for less than 1 month
  • September 19, 2013

"I started taking this a few days ago to replace Seroquel for depression and insomnia. It was terrible the first day, it made me so dizzy I couldn't even sit up, and after that, it just made me drowsy. I couldn't sleep at all and had to resort to taking Seroquel."

2 / 10
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49 Report
  • Anonymous
  • July 23, 2011

"At first, I was taking 50 mg of trazodone for insomnia after withdrawing off opioids. Now I take Celexa and trazodone together. I have taken my trazodone for a week, and I can tell the difference. I lack motivation, I just want to sit on the couch all day. I barely even want to shower. I figured I could stop taking it because I could fall asleep just fine, but I couldn't be more wrong. I'm definitely going back on it to help stabilize my moods since I didn't realize how much it really does help."

9 / 10
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53 Report
  • Alpha...
  • Taken for 1 to 6 months
  • October 11, 2021

"I have to stress don't take everyone's review as a given how trazodone will effect you. Prior to taking the tablet I read reviews and was initially terrified by the reports of negative side effects and people's bad experiences. Unfortunately there will always be more negative reports than good as people don't really feel the need to comment on the good. That's where my review comes in, my personal experience is extremely different to what I had read. Other than a constant headache I have to say this tablet has been a god send for my depression. It's taken away any and all negative thoughts and replaced them with a positive happy version of myself. Plus the extra sleep is an added bonus. I have to stress..... Just give this tablet a chance, it might not work but it is definitely worth the gamble."

9 / 10
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17 Report
  • MrsRoss
  • Taken for 1 to 6 months
  • July 2, 2017

"I had been having horrible anxiety and couldn't sleep. I would sleep for an hour, and my brain would race with a to-do list. Since I already was on medication for depression, my Dr. prescribed Trazodone. The first day was hell. Woke up several times during the night, head pounded the next day, and I was in a fog all day. I wanted to stop but tried it again after talking to my Dr. I slept better the second night but still woke up with a headache. I didn't have the fog the next day. By the third day, I was fine, sleeping like a normal person and able to function during the day. Found out I was getting the headache and the foggy feeling because I was not allowing myself enough time to sleep."

10 / 10
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33 Report
  • Avila
  • March 14, 2020

"Was on trazodone for a year for severe anxiety and mild depression,50 mg for 2 months then upped to 100mg. Went off them a month ago. They helped with the anxiety a lot, associated with therapy ( I was agoraphobic and now only have very occasional easily manageable spikes of anxiety ) but made my energy levels drop and made me feel like a zombie. I was also sleeping too much (9+ hours a night still feeling tired in the morning, nearly impossible to wake up most days). I went from mild to severe depression as the complete lack of energy prevented me from doing anything. Was relying on energy drinks/caffeine/supplements to get through the day. I stopped cold turkey as I couldn't stand them anymore, the withdrawals are truly horrible during the first week : hot flashes, high anxiety, irritability etc. Feel a million times better now. Only rating 3 because of significant help with anxiety."

3 / 10
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23 Report
  • Anonymous
  • February 21, 2011

"I was prescribed Trazodone 50 MG about 5 years ago when I went to my doctor complaining of horrible night sweats during my lengthy menopause, and I was not getting a restful night of sleep. He prescribed it for me more for the night sweats than the lack of sleep. My doctor was right… It really helped stop my night sweats. I stopped taking the medication for a while, and the night sweats and sleepless nights came back within a few days. I immediately started the medication again, and problem solved. I sleep great and rarely have night sweats, so that makes my husband very happy, as he no longer has to freeze to death with my A/C’s thermostat down so low all the time. Also, another note… this medication did not give me any withdrawal symptoms."

9 / 10
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51 Report
  • Alc
  • Taken for 1 to 6 months
  • April 4, 2020

"I switched to trazodone because I was barely sleeping while on a previous antidepressant, it helped with sleep but I had nightmares (which I hadn’t had in years). After a couple months on trazodone I became angry all the time and impulsive...So I had to get off of it. It also slightly helped with the depression."

3 / 10
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21 Report
  • Looper
  • Taken for 1 to 6 months
  • March 27, 2021

"I've tried so many medications for depression over the years nothing worked. I had severe depression last winter. I was put on trazadone because I'm sure it worked before. It is the best antidepressant for me. Doctor just upped dosage to give me full relief. Only side effect is weird dreams. Also I was having trouble sleeping and it fixed that without feeling groggy. Bonus no sexual side effects"

10 / 10
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17 Report
  • Hansjan
  • Taken for 6 months to 1 year
  • June 14, 2021

"I managed to go ten years without taking anything then my restless leg started up terribly on an evening resulting in a major lack of sleep. My sleep pattern went out the window. I was prescribed a dose of 150mg but I only take 100mg a night and so keep a few spare trazadone for if ever I feel my dose needs upping. I’ve been taking 100mg trazadone for about 6 months now. My restless leg almost stopped immediately. Once you get over the initial first few weeks and let the trazadone get into your system it works amazingly well. I take 100mg about 30 minutes before sleep. I have bipolar too and occasional depression with anxiety and mood swings. The trazadone has completely calmed all that side of me down and definitely helps with sleep. The first few weeks can be tough with the headaches, dry mouth, and brain fog. But once it’s in your system it worked for me very well"

9 / 10
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16 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.