Marezine

Generic Name: cyclizine (SYE-kli-zeen)
Brand Name: Marezine

Marezine is used for:

Preventing and treating nausea, vomiting, and dizziness associated with motion sickness. It may also be used for other conditions as determined by your doctor.

Marezine is an anticholinergic. It works by blocking a chemical messenger in the brain, which helps to reduce or prevent vomiting.

Do NOT use Marezine if:

  • you are allergic to any ingredient in Marezine
  • you are taking sodium oxybate (GHB) or anticholinergics (eg, scopolamine)

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Is it Safe to Give Human Medicine to Pets?

Always get your pet's drug and dose recommendation from the veterinarian.

Before using Marezine:

Some medical conditions may interact with Marezine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • you have asthma; chronic obstructive pulmonary disease (COPD); chronic bronchitis or emphysema; shortness of breath or difficulty breathing; a blockage of the stomach, intestine, or urinary tract; enlargement of the prostate; difficulty urinating; or glaucoma
  • if you have recently had surgery

Some MEDICINES MAY INTERACT with Marezine. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur
  • Anticholinergics (eg, scopolamine) because the risk of side effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Marezine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Marezine:

Use Marezine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Marezine may be taken with or without food.
  • For prevention of motion sickness, take Marezine at least 30 minutes before activity or travel.
  • Use Marezine exactly as directed on the package, unless instructed differently by your doctor. If you are taking Marezine without a prescription, follow any warnings and precautions on the label.
  • If you miss a dose of Marezine and are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Marezine.

Important safety information:

  • Marezine may cause drowsiness or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Marezine. Using Marezine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Avoid drinking alcohol or taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Marezine. Marezine will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Marezine.
  • Do not exceed the recommended dose or use Marezine longer than prescribed without checking with your doctor.
  • Marezine is not recommended for use in CHILDREN younger than 6 years of age without checking with your doctor. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Marezine during pregnancy. It is unknown if Marezine is excreted in breast milk. If you are or will be breast-feeding while you are using Marezine, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Marezine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Drowsiness; dry mouth.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include drowsiness; hallucinations; seizures; unusual excitability; very slow or shallow breathing.

Proper storage of Marezine:

Store Marezine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Marezine out of the reach of children and away from pets.

General information:

  • If you have any questions about Marezine, please talk with your doctor, pharmacist, or other health care provider.
  • Marezine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Marezine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Marezine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Marezine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Marezine.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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