Cyclizine Side Effects

Brand Names: Bonine for Kids

Please note - some side effects for Cyclizine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Cyclizine - for the Consumer

Cyclizine

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Cyclizine:

Drowsiness; dry mouth.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

Cyclizine Chewable

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Cyclizine Chewable:

Drowsiness; dry mouth.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

Side Effects by Body System

Nervous system

Nervous system side effects have included drowsiness and sedation in many patients. Motor skills may be impaired. Cyclizine may also cause restlessness, excitation, nervousness, and insomnia.

Lingual-facial-buccal dyskinesias and generalized chorea occurred in an elderly patient, most probably due to the anticholinergic activity of cyclizine.

Cardiovascular

Cardiovascular side effects have included hypotension, tachycardia, and palpitations. Cardiovascular changes recorded after intravenous administration of cyclizine have included increase in heart rate, decrease in cardiac output, and increases in right atrial, pulmonary arterial, pulmonary artery wedge, and systemic arterial pressures.

Gastrointestinal

Gastrointestinal side effects have been mild in nature. These have included nausea, dry mouth, and constipation.

Ocular

Ocular side effects have included blurred vision, diplopia, and dry eyes due to its anticholinergic effects.

Genitourinary

Genitourinary side effects have included urinary retention and dysuria.

Hepatic

Hepatic side effects have included a case report of hepatitis in at least one child. This side effect was confirmed upon drug rechallenge.

Hypersensitivity

Hypersensitivity side effects have included fixed drug eruptions.

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