Generic Name: nifedipine (nye FED i peen)
Brand Names: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL
What is Adalat?
Adalat (nifedipine) is in a class of drugs called calcium channel blockers. Nifedipine relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.
Adalat is used to treat hypertension (high blood pressure) and angina (chest pain).
Adalat may also be used for other purposes not listed in this medication guide.
Important information about Adalat
You should not use Adalat if you are allergic to nifedipine.
Before taking Adalat, tell your doctor if you have kidney or liver disease (especially cirrhosis), coronary artery disease, congestive heart failure, or digestive problems.
If you need surgery, tell the surgeon ahead of time that you are using Adalat. You may need to stop using the medicine for a short time.
Many drugs can interact with Adalat. Tell your doctor about all other medications you use.
Do not stop taking Adalat without first talking to your doctor, even if you feel fine. Stopping suddenly may make your condition worse. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Before taking Adalat
You should not use Adalat if you are allergic to nifedipine.
If you have any of these other conditions, your doctor may need to adjust your dose of Adalat or order special tests:
- kidney disease;
- liver disease (especially cirrhosis);
coronary artery disease;
congestive heart failure; or
FDA pregnancy category C. It is not known whether Adalat will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Nifedipine can pass into breast milk and may harm a nursing baby. Do not use Adalat without telling your doctor if you are breast-feeding a baby.
See also: Adalat pregnancy and breastfeeding warnings (in more detail)
How should I take Adalat?
Take Adalat exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results.
Take the Adalat CC tablet on an empty stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. These conditions can lead to severely low blood pressure. If you need surgery, tell the surgeon ahead of time that you are using Adalat. You may need to stop using the Adalat for a short time. Do not stop taking Adalat without first talking to your doctor, even if you feel fine. Stopping suddenly may make your condition worse. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Your blood pressure will need to be checked often and you may need other blood tests at your doctor's office. Visit your doctor regularly.
Store Adalat at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra Adalat to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe dizziness, pounding heartbeats, nausea, vomiting, and feeling like you might pass out.
What should I avoid while taking Adalat?
Grapefruit and grapefruit juice may interact with Adalat and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Drinking alcohol can lower your blood pressure further and may increase certain side effects of Adalat.
Adalat side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Adalat: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect while using Adalat such as:
feeling like you might pass out;
feeling short of breath, swelling in your hands or feet;
fast or pounding heartbeats;
numbness or tingly feeling;
jaundice (yellowing of the skin or eyes); or
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.
Less serious Adalat side effects may include:
drowsiness, tired feeling;
nausea, constipation, diarrhea, stomach pain;
sleep problems (insomnia);
mild rash or itching;
joint pain, leg cramps;
warmth, redness, or tingly feeling under your skin; or
urinating more than usual.
This is not a complete list of Adalat side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Adalat side effects (in more detail)
What other drugs will affect Adalat?
Tell your doctor about all other medicines you use, especially:
fentanyl (Actiq, Duragesic, Fentora) or other narcotic pain medications;
St. John's wort;
rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate) or rifapentine (Priftin);
a blood thinner such as warfarin (Coumadin);
an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), or erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin);
antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);
a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), timolol (Blocadren), and others;
a heart rhythm medication such as quinidine (Quin-G) or flecaininde (Tambocor);
HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), or ritonavir (Norvir, Kaletra, or saquinavir (Invirase);
medicines used to prevent organ transplant rejection, such as sirolimus (Rapamune) or tacrolimus (Prograf);
other heart or blood pressure medications such as benazepril (Lotensin), diltiazem (Cartia, Cardizem), doxazosin (Cardura), or verapamil (Calan, Covera, Isoptin, Verelan); or
seizure medication such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Solfoton), or phenytoin (Dilantin).
This list is not complete and other drugs may interact with Adalat. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More Adalat resources
- Adalat CC sustained-release tablets MedFacts Consumer Leaflet (Wolters Kluwer)
- Adalat CC Advanced Consumer (Micromedex) - Includes Dosage Information
- Adalat CC Prescribing Information (FDA)
- Afeditab CR Prescribing Information (FDA)
- Nifediac CC Prescribing Information (FDA)
- Nifedical XL Prescribing Information (FDA)
- Nifedipine Professional Patient Advice (Wolters Kluwer)
- Nifedipine Monograph (AHFS DI)
- Procardia Prescribing Information (FDA)
- Procardia XL Prescribing Information (FDA)
- nifedipine MedFacts Consumer Leaflet (Wolters Kluwer)
Where can I get more information?
- Your pharmacist can provide more information about Adalat.
- Remember, keep this and all other medicines out of the reach of children. Never share your medicines with others and only use Adalat for the condition prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
Copyright 1996-2010 Cerner Multum, Inc. Version: 9.01. Revision Date: 05/19/2010 12:04:36 PM.