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Tindamax Side Effects

Generic name: tinidazole

Medically reviewed by Drugs.com. Last updated on Feb 1, 2025.

Note: This document provides detailed information about Tindamax Side Effects associated with tinidazole. Some dosage forms listed on this page may not apply specifically to the brand name Tindamax.

Applies to tinidazole: oral tablet.

Important warnings This medicine can cause some serious health issues

Oral route (tablet)

Carcinogenicity has been seen in mice and rats treated chronically with metronidazole, another nitroimidazole agent.

Although such data have not been reported for tinidazole, the two drugs are structurally related and have similar biologic effects.

Limit use of tinidazole to approved indication only.

Avoid chronic use.

Precautions

It is important that your doctor check your progress at regular visits to make sure that the infection is cleared up. Blood tests may be needed to check for unwanted effects.

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Do not use this medicine if you have taken disulfiram (Antabuse®) within the last two weeks. Also, do not take alcohol or alcoholic products (eg, propylene glycol) during treatment with this medicine and for at least 3 days after your last dose.

This medicine may increase your risk for cancer. Talk to your doctor about this risk.

Check with your doctor right away if you have burning, numbness, tingling, or painful sensations in the arms, hands, legs, or feet. These could be symptoms of a condition called peripheral neuropathy.

This medicine may cause a vaginal yeast infection. Check with your doctor right away if you have itching of the vagina or genitals or thick, white vaginal discharge with mild or no odor.

If you are taking this medicine for trichomoniasis (an infection of the sex organs in men or women), your doctor may want to treat your sexual partner at the same time you are being treated, even if he or she has no symptoms. Also, it may be desirable to use a condom (rubber) during intercourse. These measures will help to keep you from getting the infection back again from your partner. If you have any questions about this, talk with your doctor.

If you plan to have children, talk with your doctor before using this medicine. Some men using this medicine have become infertile (unable to have children).

Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Common side effects of Tindamax

Some side effects of tinidazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • bitter taste
  • metallic taste

Less common side effects

  • acid or sour stomach
  • belching
  • cramps
  • difficulty having a bowel movement
  • dizziness
  • general feeling of discomfort or illness
  • headache
  • heartburn
  • indigestion
  • loss of appetite
  • pain or discomfort in the chest, upper stomach, or throat
  • vomiting
  • weight loss

Rare side effects

  • body aches or pain
  • coating on tongue
  • depression
  • hoarseness
  • mood or mental changes
  • runny nose
  • tender, swollen glands in the neck
  • voice changes

Incidence not known

  • darkened urine
  • diarrhea
  • difficulty in moving
  • feeling of constant movement of self or surroundings
  • giddiness
  • lightheadedness
  • muscle pain or stiffness
  • pain, swelling, or redness in joints
  • sensation of spinning
  • shakiness and unsteady walk
  • sleepiness
  • swelling of the mouth
  • tongue discoloration
  • trembling, or other problems with muscle control or coordination
  • trouble sleeping
  • unable to sleep
  • white or brownish vaginal discharge
  • white patches in the mouth or throat or on the tongue

Serious side effects of Tindamax

Along with its needed effects, tinidazole (the active ingredient contained in Tindamax) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tinidazole:

Rare side effects

  • chest tightness
  • change in consciousness
  • cough
  • loss of consciousness
  • trouble breathing

Incidence not known

  • black, tarry stools
  • bleeding gums
  • blood in urine or stools
  • burning, numbness, tingling, or painful sensations
  • chest pain
  • chills
  • difficulty swallowing
  • fast, irregular, pounding, or racing heartbeat or pulse
  • fever
  • hives, itching, rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • lower back or side pain
  • nausea
  • painful or difficult urination
  • pale skin
  • pinpoint red spots on the skin
  • reddening of the skin, especially around ears
  • seizures
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling of eyes, face, or inside of the nose
  • swollen glands
  • ulcers
  • unsteadiness or awkwardness
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • weakness in the arms, hands, legs, or feet

For healthcare professionals

Applies to tinidazole: compounding powder, oral tablet.

General adverse events

Reported side effects were typically mild, infrequent, and self-limiting. Gastrointestinal side effects were reported most often.[Ref]

Gastrointestinal

Nervous system

Other

Dermatologic

In a study involving 450 patients with fixed drug eruptions, 8 patients were found to have this oral drug as the probable causative agent. The fixed drug eruptions varied as to duration, shape and size, symptoms, number of lesions, and body site(s) affected. The study did not break these factors down for each individual causative agent.[Ref]

Metabolic

Genitourinary

Respiratory

Psychiatric

Hematologic

Hypersensitivity

Severe acute hypersensitivity reactions have been reported during initial or subsequent exposure to this drug.[Ref]

Hepatic

Renal

Cardiovascular

Musculoskeletal

See also:

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2004) "Product Information. Tindamax (tinidazole)." Presutti Laboratories Inc

4. Mahboob A, Haroon TS (1998) "Drugs causing fixed eruptions: a study of 450 cases." Int J Dermatol, 37, p. 833-8

Further information

Tindamax side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.