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Somatrogon Side Effects

Medically reviewed by Drugs.com. Last updated on Aug 10, 2024.

Applies to somatrogon: subcutaneous solution.

Precautions

If you will be taking this medicine for a long time, it is very important that your doctor check you and your child's progress at regular visits. Blood and urine tests may be needed to check for any problems or unwanted effects that may be caused by this medicine.

This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which are life-threatening and require immediate medical attention. Tell your doctor right away if you or your child have a rash, itching, swelling of the face, tongue, or throat, trouble breathing, or chest pain after receiving this medicine.

Never share pens with others under any circumstances. It is not safe for one pen to be used for more than one person. Sharing needles or pens can result in transmission of hepatitis viruses, HIV, or other bloodborne illnesses.

Using this medicine may increase your or your child's risk of getting cancer. Talk to your doctor if you have concerns about this risk.

This medicine may affect blood sugar levels. Check with your doctor if you notice a change in the results of your or your child's blood or urine sugar tests or if you have any questions.

This medicine may cause an increased pressure in the head. Check with your doctor immediately if headache, nausea, vomiting, blurred vision, or any other change in vision occurs during treatment. Your doctor may want you to have your or your child's eyes checked by an ophthalmologist (eye doctor).

Check with your doctor right away if you or your child have decrease in amount of urine, noisy, rattling breathing, swelling of the fingers, hands, feet, or lower legs, or weight gain. These may be symptoms of fluid retention (extra water in the body).

Check with your doctor right away if you have darkening of skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. These may be symptoms of an adrenal gland problem (hypoadrenalism).

Pancreatitis (inflammation of the pancreas) has occurred rarely in some patients receiving somatrogon-ghla. Tell your doctor right away if you or your child have sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness.

Check with your doctor right away if your child has hip and knee pain or limp. These may be symptoms of slipped capital femoral epiphysis (hip bone dislocation).

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of somatrogon

Along with its needed effects, somatrogon may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking somatrogon:

More common side effects

  • pale skin
  • trouble breathing
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Less common side effects

  • constipation
  • depressed mood
  • dry skin and hair
  • feeling cold
  • hair loss
  • hoarseness or husky voice
  • muscle cramps and stiffness
  • slowed heartbeat
  • weight gain

Incidence not known

  • bloating
  • blurred vision
  • change in ability to see colors, especially blue or yellow
  • chest tightness
  • chills
  • cough
  • darkened urine
  • darkening of the skin
  • decrease amount in urine
  • diarrhea
  • difficulty swallowing
  • dizziness
  • dry mouth
  • fainting
  • fast heartbeat
  • flushed, dry skin
  • headache
  • hives, itching, skin rash
  • increased hunger
  • increased thirst
  • increased urination
  • indigestion
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of appetite
  • loss of consciousness
  • mental depression
  • nausea
  • noisy, rattling breathing
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • stomachache
  • sweating
  • swelling of the fingers, hands, feet, or lower legs
  • unexplained weight loss
  • vomiting
  • yellow eyes or skin

Other side effects of somatrogon

Some side effects of somatrogon may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • cough producing mucus
  • difficulty in moving
  • earache
  • joint pain
  • muscle pain
  • redness or swelling in the ear
  • sore throat
  • stuffy or runny nose

For healthcare professionals

Applies to somatrogon: subcutaneous solution.

General adverse events

Adverse reactions occurring in 5% of patients or greater included injection site reactions, nasopharyngitis, headache, pyrexia, anemia, cough, vomiting, hypothyroidism, abdominal pain, rash, and oropharyngeal pain.[Ref]

Dermatologic

Endocrine

Gastrointestinal

Hematologic

Hypersensitivity

Immunologic

Local

Metabolic

Musculoskeletal

Nervous system

Ocular

Oncologic

Other

Respiratory

See also:

References

1. (2023) "Product Information. Ngenla (somatrogon)." Pfizer U.S. Pharmaceuticals Group

Further information

Somatrogon side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.