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Somapacitan-beco Side Effects

Medically reviewed by Drugs.com. Last updated on Jun 29, 2024.

Applies to somapacitan-beco: subcutaneous solution.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

This medicine may increase your risk for cancer, including skin cancer. Call your doctor right away if you have changes in your moles, birthmarks, or color of the skin.

Check with doctor right away if you have anxiety, blurred vision, chills, cold sweats, coma, confusion, cool, pale skin, depression, dizziness, fast heartbeat, headache, increased hunger, nausea, nervousness, nightmares, seizures, shakiness, slurred speech, or unusual tiredness or weakness. These may be symptoms of hyperglycemia (high blood sugar).

This medicine may increase pressure in your head (intracranial hypertension). Check with your doctor right away if you have confusion, headache, severe nausea, vomiting, or vision changes.

This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving this medicine.

This medicine may cause fluid retention (excess fluid build-up in the body). Call your doctor right away if you have burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, joint or muscle pain, swelling of the hands, ankles, feet, or lower legs, or weight gain.

Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting. These may be symptoms of an adrenal gland problem (eg, hypoadrenalism).

Thyroid problems (eg, hypothyroidism) may occur during treatment with this medicine. Call your doctor right away if you have constipation, depressed mood, dry skin and hair, feeling cold, hair loss, hoarseness or husky voice, muscle cramps and stiffness, slow heartbeat, weight gain, or unusual tiredness or weakness.

Check with your doctor right away if you have bloating, chills, constipation, darkened urine, fast heartbeat, fever, indigestion, loss of appetite, nausea, pain in the stomach, side, or abdomen, possibly radiating to the back, vomiting, or yellow eyes or skin. These may be symptoms of pancreatitis (swelling of the pancreas).

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of somapacitan-beco

Along with its needed effects, somapacitan-beco may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking somapacitan-beco:

More common side effects

  • bloating
  • blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in ability to see colors, especially blue or yellow
  • chills
  • constipation
  • cough
  • darkened urine
  • darkening of the skin
  • depressed mood
  • diarrhea
  • difficulty swallowing
  • dizziness
  • dry mouth
  • dry skin and hair
  • fainting
  • fast heartbeat
  • feeling cold
  • fever
  • flushed, dry skin
  • fruit-like breath odor
  • hair loss
  • headache
  • hives, itching, skin rash
  • hoarseness or husky voice
  • increased hunger
  • increased thirst
  • increased urination
  • indigestion
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • loss of appetite
  • loss of consciousness
  • loss of fat or tissue weakness in the skin area at the injection site
  • mental depression
  • muscle cramps and stiffness
  • nausea
  • nervousness
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pale skin
  • persistent non-healing sore
  • pink growth
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • reddish patch or irritated area
  • shiny bump
  • slow or fast heartbeat
  • stomach pain
  • sweating
  • swelling
  • thickening of the skin
  • tightness in the chest
  • trouble breathing
  • unexplained weight loss
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting
  • weight gain
  • white, yellow or waxy scar-like area
  • yellow eyes or skin

Other side effects of somapacitan-beco

Some side effects of somapacitan-beco may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • acid or sour stomach
  • back pain
  • belching
  • difficulty in moving
  • heartburn
  • muscle pain or stiffness
  • pain in the joints
  • stomach discomfort or upset
  • trouble sleeping

For healthcare professionals

Applies to somapacitan-beco: subcutaneous solution.

General adverse events

In pediatric patients with growth hormone deficiency (GHD): Common adverse reactions occurring in 5% or more of patients receiving this drug include nasopharyngitis, headache, fever, extremity pain, and injection site reactions.

In adult patients with GHD: Adverse reactions occurring in over 2% of patients treated with this drug comprise back pain, joint pain, indigestion, sleep disturbances, dizziness, tonsillitis, peripheral edema, vomiting, adrenal insufficiency, high blood pressure, elevated blood creatine phosphokinase levels, weight gain, and anemia.[Ref]

Cardiovascular

Dermatologic

Endocrine

Gastrointestinal

Nausea/vomiting included vomiting (4.5%) and nausea (1.5%); Diarrhea included diarrhea (2.3%), gastroenteritis viral (1.5%), and gastrointestinal viral infection (0.8%).[Ref]

Hematologic

Hypersensitivity

Local

Injection site reaction included injection site bruising (1.5%), injection site pain (1.5%), injection site hematoma (1.5%), injection site reaction (0.8%), and injection site swelling (0.8%).[Ref]

Metabolic

Elevated phosphate and creatine phosphokinase occurred intermittently and were non-progressive.[Ref]

Musculoskeletal

Nervous system

Oncologic

Other

Pyrexia included pyrexia (8.3%) and hyperthermia (0.8%); pain in extremity included pain in extremity (9.1%) and growing pains (0.8%).[Ref]

Respiratory

Nasopharyngitis included nasopharyngitis (11.4%), rhinitis (3.8%), pharyngitis streptococcal (0.8%), acute sinusitis (0.8%), nasal congestion (0.8%), pharyngitis (0.8%), and sinusitis (0.8%).[Ref]

See also:

References

1. (2022) "Product Information. Sogroya (somapacitan)." Novo Nordisk Pharmaceuticals Pty Ltd, Sogroya PI v2.0

2. (2020) "Product Information. Sogroya (somapacitan)." Novo Nordisk Pharmaceuticals Inc

Further information

Somapacitan-beco side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.