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Sodium nitrite Side Effects

For the Consumer

Applies to sodium nitrite: intravenous solution

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of methemoglobinemia like a blue or gray color of the lips, nails, or skin; a heartbeat that does not feel normal; seizures; very bad dizziness or passing out; very bad headache; feeling very sleepy; feeling tired or weak; or shortness of breath.
  • Very bad dizziness or passing out.
  • A fast heartbeat.
  • Feeling confused.
  • Blurred eyesight.
  • Numbness and tingling.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Dizziness.
  • Flushing.
  • Headache.
  • Upset stomach or throwing up.
  • Bad taste in your mouth.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to sodium nitrite: compounding powder, intravenous solution

Cardiovascular

Cardiovascular side effects have included syncope, hypotension, tachycardia, palpitations, and dysrhythmia.[Ref]

Dermatologic

Dermatologic side effects have included urticaria.[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, and abdominal pain.[Ref]

General

General side effects have included fatigue, weakness, and diaphoresis.[Ref]

Hematologic

Hematologic side effects have included methemoglobinemia.[Ref]

Local

Local side effects have included injection site tingling,[Ref]

Metabolic

Metabolic side effects have included acidosis and cyanosis.[Ref]

Nervous system

Nervous system side effects have included generalized numbness and tingling, lightheadedness, headache, dizziness, blurred vision, seizures, confusion, and coma.[Ref]

Psychiatric

Psychiatric side effects have included anxiety.[Ref]

Respiratory

Respiratory side effects have included tachypnea and dyspnea.[Ref]

References

1. "Product Information. Sodium Nitrite (sodium nitrite)." Hope Pharmaceuticals, Scottsdale, AZ.

Some side effects of sodium nitrite may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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