Sincalide Side Effects
For the Consumer
Applies to sincalide: intravenous powder for solution
Along with its needed effects, sincalide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking sincalide:
Less Common or Rare
Some side effects of sincalide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Abdominal or stomach pain, cramps, or discomfort
Less Common or Rare
- flushing or redness of skin
- increased sweating
- urge to have bowel movement
For Healthcare Professionals
Applies to sincalide: injectable powder for injection, intravenous powder for injection
Gastrointestinal side effects have included abdominal discomfort or pain and nausea. Rapid IV injection of 0.04 mcg sincalide per kg would be expected to cause transient abdominal cramping. These side effects are usually manifestations of the physiologic action of the drug, including delayed gastric emptying and increased intestinal motility. These side effects occurred in approximately 20% of patients but they are not to be construed as necessarily indicating an abnormality of the biliary tract unless there is other clinical or radiologic evidence of disease.[Ref]
Reactions to sincalide are usually mild and of short duration. Adverse reactions including vomiting, flushing, sweating, rash, hypotension, hypertension, shortness of breath, urge to defecate, headache, diarrhea, sneezing, and numbness were less than 1%. Dizziness was reported in approximately 2% of patients. These manifestations are usually attenuated by a slower injection rate.[Ref]
1. "Product Information. Kinevac (sincalide)." Bristol-Myers Squibb, Princeton, NJ.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about sincalide
Other brands: Kinevac